Patents by Inventor Francisco Lopez-Jimenez

Francisco Lopez-Jimenez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230089991
    Abstract: Systems, methods, devices, and techniques for estimating a heart disease prediction of a mammal. An electrocardiogram (ECG) procedure is performed on a mammal, and a computer system obtains ECG data that describes results of the ECG over a period of time. The system provides a predictive input that is based on the ECG data to a predictive model, such as a neural network or other machine-learning model. In response, the predictive model processes the input to generate an estimated heart disease predictive characteristic of the mammal. The system outputs the estimated heart disease prediction of the mammal for presentation to a user.
    Type: Application
    Filed: November 7, 2022
    Publication date: March 23, 2023
    Inventors: Itzhak Zachi Attia, Paul A. Friedman, Francisco Lopez-Jimenez, Suraj Kapa
  • Publication number: 20220218289
    Abstract: Apparatuses and methods are provided to predict or diagnose an ischemic event, such as a stroke or a transient ischemic attack (TIA). A machine-learning model such as a neural network is generated that allows for recognition of an ECG consistent with an ischemic event. A system is trained and used to process a recording of ECG data from a patient to generate a prediction indicating a likelihood that the patient will experience a stroke. In other examples, a system is trained and used to process a recording of ECG data from a patient and detect an ischemic event for the patient who did not appear to have such an ischemic event.
    Type: Application
    Filed: March 31, 2022
    Publication date: July 14, 2022
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Itzhak Zachi Attia, Paul A. Friedman, Samuel J. Asirvatham, Peter A. Noseworthy, Suraj Kapa, Francisco Lopez-Jimenez
  • Publication number: 20220189634
    Abstract: Provided herein are methods, systems, and computer program products for the detection of pulmonary hypertension comprising receiving voltage-time data of a plurality of leads of an electrocardiograph of a subject; generating a feature vector from the voltage-time data; providing the feature vector to a pretrained learning system; and receiving from the pretrained learning system an indication of the presence or absence of pulmonary hypertension in the subject.
    Type: Application
    Filed: October 13, 2021
    Publication date: June 16, 2022
    Inventors: Tyler Wagner, Samir Awasthi Awasthi, Venkataramanan Soundararajan, Murali Aravamudan, Corinne Carpenter, Katherine Carlson, Itzhak Zachi Attia, Paul A. Friedman, Samuel J. Asirvatham, Surai Kapa, Francisco Lopez-Jimenez, Hilary M. Dubrock
  • Patent number: 11317872
    Abstract: Apparatuses and methods are provided to predict or diagnose an ischemic event, such as a stroke or a transient ischemic attack (TIA). A machine-learning model such as a neural network is generated that allows for recognition of an ECG consistent with an ischemic event. A system is trained and used to process a recording of ECG data from a patient to generate a prediction indicating a likelihood that the patient will experience a stroke. In other examples, a system is trained and used to process a recording of ECG data from a patient and detect an ischemic event for the patient who did not appear to have such an ischemic event.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: May 3, 2022
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Itzhak Zachi Attia, Paul A. Friedman, Samuel J. Asirvatham, Peter A. Noseworthy, Suraj Kapa, Francisco Lopez-Jimenez
  • Publication number: 20210401347
    Abstract: Systems and methods for assessing the condition of a heart of an individual. A system obtains electrocardiogram (ECG) data that describes a result of an ECG of the individual. The ECG data can be provided to a machine-learning model, which processes the data and generates an output indicative of the condition of the heart. The output relates to a level of troponin in a bloodstream of the individual. The system can then provide the output of the machine-learning model to a post-processing resource.
    Type: Application
    Filed: June 24, 2021
    Publication date: December 30, 2021
    Inventors: Paul A. Friedman, Itzhak Zachi Attia, Allan S. Jaffe, Suraj Kapa, Francisco Lopez-Jimenez, Yader B. Sandoval Pichardo
  • Publication number: 20210361217
    Abstract: Systems, methods, devices, and other techniques for estimating the age and sex of a person through analysis of an electrocardiogram (ECG) recording for the person. Some aspects include recording an ECG of a person, processing data representing the ECG with an age-estimation neural network to generate an estimated age of the person, and outputting an indication of the estimated age of the person. Other aspects include processing the ECG with a sex prediction neural network to generate a predicted sex of the person and outputting an indication of the predicted sex of the person.
    Type: Application
    Filed: January 11, 2019
    Publication date: November 25, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Itzhak Zachi Attia, Paul A. Friedman, Suraj Kapa, Francisco Lopez-Jimenez
  • Publication number: 20200397313
    Abstract: Systems, methods, devices, and techniques for estimating an ejection-fraction characteristic of a mammal. An electrocardiogram (ECG) procedure is performed on a mammal, and a computer system obtains ECG data that describes results of the ECG over a period of time. The system provides a predictive input that is based on the ECG data to an ejection-fraction predictive model, such as a neural network or other machine-learning model. In response, the ejection-fraction predictive model processes the input to generate an estimated ejection-fraction characteristic of the mammal. The system outputs the estimated ejection-fraction characteristic of the mammal for presentation to a user.
    Type: Application
    Filed: October 4, 2018
    Publication date: December 24, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Itzhak Zachi Attia, Paul A. Friedman, Francisco Lopez-Jimenez, Suraj Kapa
  • Publication number: 20200069416
    Abstract: A replacement heart valve device including a stent member that is to be compressible and expandable, and a dry valve directly sutured to the stent member. The dry valve includes two to four leaflets made of a treated pericardium tissue that has been gas sterilized.
    Type: Application
    Filed: April 10, 2019
    Publication date: March 5, 2020
    Inventors: David PANIAGUA, R. David FISH, Eduardo INDUNI, Carlos MEIJA, Francisco LOPEZ-JIMENEZ
  • Publication number: 20190209300
    Abstract: A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of glutaraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent.
    Type: Application
    Filed: March 31, 2017
    Publication date: July 11, 2019
    Inventors: David PANIAGUA, R. FISH, Eduardo INDUNI, Carlos MEIJA, Francisco LOPEZ-JIMENEZ
  • Publication number: 20190183431
    Abstract: Apparatuses and methods are provided to predict or diagnose an ischemic event, such as a stroke or a transient ischemic attack (TIA). A machine-learning model such as a neural network is generated that allows for recognition of an ECG consistent with an ischemic event. A system is trained and used to process a recording of ECG data from a patient to generate a prediction indicating a likelihood that the patient will experience a stroke. In other examples, a system is trained and used to process a recording of ECG data from a patient and detect an ischemic event for the patient who did not appear to have such an ischemic event.
    Type: Application
    Filed: December 14, 2018
    Publication date: June 20, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Itzhak Zachi Attia, Paul A. Friedman, Samuel J. Asirvatham, Peter A. Noseworthy, Suraj Kapa, Francisco Lopez-Jimenez
  • Publication number: 20170265997
    Abstract: A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of glutaraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent.
    Type: Application
    Filed: March 31, 2017
    Publication date: September 21, 2017
    Inventors: David PANIAGUA, R. David FISH, Eduardo INDUNI, Carlos MEIJA, Francisco LOPEZ-JIMENEZ
  • Patent number: 8308797
    Abstract: The present invention comprises a percutaneously implantable replacement heart valve device and a method of making same. The replacement heart valve device comprises a stent member made of stainless steel or self-expanding nitinol, a biological tissue artificial valve means disposed within the inner space of the stent member. An implantation and delivery system having a central part which consists of a flexible hollow tube catheter that allows a metallic wire guide to be advanced inside it. The endovascular stented-valve is a glutaraldehyde fixed bovine pericardium which has two or three cusps that open distally to permit unidirectional blood flow.
    Type: Grant
    Filed: July 10, 2004
    Date of Patent: November 13, 2012
    Assignee: Colibri Heart Valve, LLC
    Inventors: David Paniagua, Eduardo Induni, Carlos Mejia, Francisco Lopez-Jimenez, R. David Fish
  • Patent number: 8109995
    Abstract: A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of glutaraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: February 7, 2012
    Assignee: Colibri Heart Valve LLC
    Inventors: David Paniagua, Eduardo Induni, Carlos Mejia, Francisco Lopez-Jimenez, R. David Fish
  • Publication number: 20090030511
    Abstract: A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of gluteraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent.
    Type: Application
    Filed: August 8, 2008
    Publication date: January 29, 2009
    Inventors: David Paniagua, Eduardo Induni, Carlos Mejia, Francisco Lopez-Jimenez, R. David Fish
  • Publication number: 20050113910
    Abstract: The present invention comprises a percutaneously implantable replacement heart valve device and a method of making same. The replacement heart valve device comprises a stent member made of stainless steel or self-expanding nitinol, a biological tissue artificial valve means disposed within the inner space of the stent member. An implantation and delivery system having a central part which consists of a flexible hollow tube catheter that allows a metallic wire guide to be advanced inside it. The endovascular stented-valve is created from a glutaraldehyde fixed biocompatible tissue material which has two or three cusps that open distally to permit unidirectional blood flow.
    Type: Application
    Filed: July 10, 2004
    Publication date: May 26, 2005
    Inventors: David Paniagua, Eduardo Induni, Carlos Mejia, Francisco Lopez-Jimenez, R. Fish