Patents by Inventor Francisco Lozano
Francisco Lozano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240128534Abstract: A cooling module for batteries of an electric or hybrid vehicle has a coolant supply line, a coolant discharge line, and a plurality of flat tubes arranged side by side, between which there is space for batteries to be cooled, each of the flat tubes being connected to the coolant supply line or the coolant discharge line. The flat tubes each carry connectors. The coolant supply line and the coolant discharge line are each assembled from a plurality of line segments connected by a connector of one of the flat tubes to one of the connectors of an adjacent flat tube. A spacer strip is arranged between adjacent flat tubes. The spacer strip delimits between itself and each of the two adjacent flat tubes spaces for batteries that are to be cooled.Type: ApplicationFiled: October 9, 2023Publication date: April 18, 2024Inventors: Christian Kroisleitner, Román Carballido, Miguel Suarez, Xoán Hermida, Francisco Lozano
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Publication number: 20240128545Abstract: A cooling module for batteries of an electric or hybrid vehicle that has a coolant supply line, a coolant discharge line, and flat tubes arranged side by side, between which there is space for batteries to be cooled. Each of the flat tubes is connected to the coolant supply line and the coolant discharge line. The flat tubes each carry connectors and the coolant supply line and the coolant discharge line are each assembled from a plurality of line segments connected by a connector of one of the flat tubes to one of the connectors of an adjacent flat tube.Type: ApplicationFiled: October 9, 2023Publication date: April 18, 2024Inventors: Christian Kroisleitner, Román Carballido, Lidia María Fontán Martinez, Óscar Abelairas, Francisco Lozano
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Publication number: 20240118042Abstract: The present description relates to a flat heat exchanger of the types which use a single working fluid circulating continuously through the inside of one or a plurality of heat transmission conduits for cooling one or more electric or electronic components or the like located in a position close to or in contact with a region of the outer part of at least one heat transmission conduit.Type: ApplicationFiled: October 4, 2023Publication date: April 11, 2024Applicant: Borgwarner Emissions Systems Spain, S.L.U.Inventors: Xoán Hermida, Francisco Lozano, David Lago, Manuel Lorenzo González, Óscar Abelairas
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Publication number: 20230381266Abstract: The present invention relates to the field of medicine and provides pharmaceutical compositions comprising one or more of the following isolated amino acid sequences comprising or, alternatively, consisting of, SEQ ID No.: 3, and/or SEQ ID No.: 1, and/or SEQ ID No.: 2, kits and conjugates comprising one or more of the above mentioned amino acid sequences. In addition, the present invention relates to the use of the pharmaceutical compositions, kits and conjugates of the present invention as a medicament, in particular in the treatment of an infectious disease, or of an inflammatory condition related to an infectious disease, or of an inflammatory disease related to the presence of a product derived from an infectious agent. The present invention also provides a device for selective binding and separation of at least one component from an aqueous solution wherein the device comprises one or more of the above mentioned amino acid sequences.Type: ApplicationFiled: April 19, 2023Publication date: November 30, 2023Inventors: Francisco LOZANO SOTO, Mario MARTÍNEZ FLORENSA
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Patent number: 11660326Abstract: The present invention relates to the field of medicine and provides pharmaceutical compositions comprising one or more of the following isolated amino acid sequences comprising or, alternatively, consisting of, SEQ. ID No.: 3, and/or SEQ. ID No.: 1, and/or SEQ ID No.: 2, kits and conjugates comprising one or more of the above mentioned amino acid sequences. In addition, the present invention relates to the use of the pharmaceutical compositions, kits and conjugates of the present invention as a medicament, in particular in the treatment of an infectious disease, or of an inflammatory condition related to an infectious disease, or of an inflammatory disease related to the presence of a product derived from an infectious agent. The present invention also provides a device for selective binding and separation of at least one component from an aqueous solution wherein the device comprises one or more of the above mentioned amino acid sequences.Type: GrantFiled: March 13, 2019Date of Patent: May 30, 2023Assignee: Sepsia Therapeutics, S.L.Inventors: Francisco Lozano Soto, Mario Martínez Florensa
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Patent number: 11324804Abstract: The present invention relates to the field of medicine and provides compositions and kits-of-parts comprising a CD6 product and Imipenem, in particular for their use in a therapeutic and/or preventive method of treatment, in a mammal including a human, of an infectious disease, or of an inflammatory condition related to an infectious disease, or of an inflammatory disease related to the presence of a product derived from an infectious agent.Type: GrantFiled: November 17, 2017Date of Patent: May 10, 2022Assignee: Sepsia Therapeutics, S.L.Inventors: Francisco Lozano Soto, Mario Martinez Florensa
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Publication number: 20210023162Abstract: The present invention relates to the field of medicine and provides pharmaceutical compositions comprising one or more of the following isolated amino acid sequences comprising or, alternatively, consisting of, SEQ. ID No.: 3, and/or SEQ. ID No.: 1, and/or SEQ ID No.: 2, kits and conjugates comprising one or more of the above mentioned amino acid sequences. In addition, the present invention relates to the use of the pharmaceutical compositions, kits and conjugates of the present invention as a medicament, in particular in the treatment of an infectious disease, or of an inflammatory condition related to an infectious disease, or of an inflammatory disease related to the presence of a product derived from an infectious agent. The present invention also provides a device for selective binding and separation of at least one component from an aqueous solution wherein the device comprises one or more of the above mentioned amino acid sequences.Type: ApplicationFiled: March 13, 2019Publication date: January 28, 2021Inventors: Francisco LOZANO SOTO, Mario MARTÍNEZ FLORENSA
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Publication number: 20200289612Abstract: The present invention relates to the field of medicine and provides compositions and kits-of-parts comprising a CD6 product and Imipenem, in particular for their use in a therapeutic and/or preventive method of treatment, in a mammal including a human, of an infectious disease, or of an inflammatory condition related to an infectious disease, or of an inflammatory disease related to the presence of a product derived from an infectious agent.Type: ApplicationFiled: November 17, 2017Publication date: September 17, 2020Inventors: Francisco LOZANO SOTO, Mario MARTINEZ FLORENSA
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Patent number: 9688294Abstract: A system includes a motion switch module, an energy storage module, a resistive module, and an interface. The motion switch module includes at least one motion activated switch that is movable between an open and a closed position responsive to movement of an axle to which the motion switch module is coupled. The energy storage module includes at least one energy storage element that discharges a stored charge responsive to a motion of the corresponding at least one motion activated switch from the open to the closed position. The resistive module includes least one resistive element that dissipates energy discharged by the corresponding at least one energy storage module. The interface is configured to provide information regarding a change in charge state of the at least one energy storage element, wherein the change in charge state corresponds to a movement of the vehicle.Type: GrantFiled: March 11, 2015Date of Patent: June 27, 2017Assignee: ALSTOM TRANSPORT TECHNOLOGIESInventors: Francisco Lozano, Andrea Malesci, Mario Papini
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Patent number: 9445582Abstract: The present invention discloses soluble isoforms of CD5 and CD6, which are scavenger-like lymphocyte receptors, for use in the prophylaxis or therapy of disorders or in therapeutic interventions, which would benefit from an exacerbated immune response to either endogenous or exogenous antigens, resulting from a decrease in lymphocyte subpopulations with regulatory functions and/or increase in lymphocyte subpopulations with effector functions. Special disorders are cell growth disorders, and chronic infections of bacterial, viral, fungal or parasitic origin. The invention also provides animal models for the study and the prophylaxis/treatment of autoimmune diseases, cancer, and chronic infections.Type: GrantFiled: May 29, 2012Date of Patent: September 20, 2016Assignees: FUNDACIO CLINIC PER A LA RECERCA BIOMEDICA, HOSPITAL CLINIC I PROVINCIAL DE BARCELONA, UNIVERSITAT DE BARCELONAInventors: Francisco Lozano Soto, Vanessa Gabriela Martinez, Rafael Fenutria Aumesquet
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Publication number: 20150274183Abstract: A system includes a motion switch module, an energy storage module, a resistive module, and an interface. The motion switch module includes at least one motion activated switch that is movable between an open and a closed position responsive to movement of an axle to which the motion switch module is coupled. The energy storage module includes at least one energy storage element that discharges a stored charge responsive to a motion of the corresponding at least one motion activated switch from the open to the closed position. The resistive module includes least one resistive element that dissipates energy discharged by the corresponding at least one energy storage module. The interface is configured to provide information regarding a change in charge state of the at least one energy storage element, wherein the change in charge state corresponds to a movement of the vehicle.Type: ApplicationFiled: March 11, 2015Publication date: October 1, 2015Inventors: Francisco Lozano, Andrea Malesci, Mario Papini
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Publication number: 20140215644Abstract: The present invention discloses soluble isoforms of CD5 and CD6, which are scavenger-like lymphocyte receptors, for use in the prophylaxis or therapy of disorders or in therapeutic interventions, which would benefit from an exacerbated immune response to either endogenous or exogenous antigens, resulting from a decrease in lymphocyte subpopulations with regulatory functions and/or increase in lymphocyte subpopulations with effector functions. Special disorders are cell growth disorders, and chronic infections of bacterial, viral, fungal or parasitic origin. The invention also provides animal models for the study and the prophylaxis/treatment of autoimmune diseases, cancer, and chronic infections.Type: ApplicationFiled: May 29, 2012Publication date: July 31, 2014Applicants: FUNDACIO CLINIC PER A LA RECERCA BIOMEDICA, UNIVERSITAT DE BARCELONA, HOSPITAL CLINIC I PROVINCIAL DE BARCELONAInventors: Francisco Lozano Soto, Vanessa Gabriela Martinez, Rafael Fenutria Aumesquet
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Patent number: 8691752Abstract: The inventors have found that CD6, a member of the Scavenger Receptor Cysteine-Rich (SRSR) superfamily expressed on human lymphocytes binds to Gram-positive and Gram-negative bacteria, as well as to other microbial structures. Thus, a CD6 product is useful for the manufacture of a medicament for therapeutic and/or preventive treatment of an infectious disease or of an inflammatory condition related to an infectious disease or to the presence of a product derived from an infectious agent in a mammal including a human. Examples of such inflammatory conditions are systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis and septic shock.Type: GrantFiled: March 27, 2008Date of Patent: April 8, 2014Assignee: Universidad de BarcelonaInventors: Maria Rosa Sarrias Fornés, Francisco Lozano Soto
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Patent number: 8404633Abstract: The present invention refers to pharmaceutical compositions comprising the soluble CD5 ectodomain and its use for the prevention and/or treatment of fungal infections and/or fungal sepsis, as well as inflammatory disorders of fungal origin.Type: GrantFiled: June 19, 2009Date of Patent: March 26, 2013Assignees: Hospital Clinic I Provincial de Barcelona, Universitat de Barcelona, Fundacio Clinic per a la Recerca BiomedicaInventors: Francisco Lozano Soto, Jorge Vera Fernandez
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Publication number: 20110195894Abstract: The present invention refers to pharmaceutical compositions comprising the soluble CD5 ectodomain and its use for the prevention and/or treatment of fungal infections and/or fungal sepsis, as well as inflammatory disorders of fungal origin.Type: ApplicationFiled: June 19, 2009Publication date: August 11, 2011Applicants: HOSPITAL CLINIC I PROVINCIAL DE BARCELONA, FUNDACIO CLINIC PER A LA RECERCA BIOMEDICA, UNIVERSITAT DE BARCELONAInventors: Francisco Lozano Soto, Jorge Vera Fernandez
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Publication number: 20100105622Abstract: The inventors have found that CD6, a member of the Scavenger Receptor Cysteine-Rich (SRSR) superfamily expressed on human lymphocytes binds to Gram-positive and Gram-negative bacteria, as well as to other microbial structures. Thus, a CD6 product is useful for the manufacture of a medicament for therapeutic and/or preventive treatment of an infectious disease or of an inflammatory condition related to an infectious disease or to the presence of a product derived from an infectious agent in a mammal including a human. Examples of such inflammatory conditions are systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis and septic shock.Type: ApplicationFiled: March 27, 2008Publication date: April 29, 2010Applicant: Universidad de BarcelonaInventors: Maria Rosa Sarrias Fornés, Francisco Lozano Soto
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Patent number: D902964Type: GrantFiled: March 26, 2018Date of Patent: November 24, 2020Inventor: Francisco Lozano