Patents by Inventor Francisco Manuel Romero Martínez

Francisco Manuel Romero Martínez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugates comprising nanoparticles coated with platinum containing compounds
    Patent number: 9023370
    Abstract: The present invention relates to conjugates of formula (I) having colloidal stability in a medium, wherein NP is a gold, silver or platinum nanoparticle; L is a linker selected from the group consisting of formula (II), formula (III), and a stereoisomer of any of the formulas (II) and (III), which is attached to the nanoparticle NP through sulfur atoms; wherein the meanings of X, n, p, Y and s are further specified in the description; and A is a platinum (II) biradical selected from the group consisting of formula (IV), formula (V) and formula (VI) including any of the stereoisomers of all of them, wherein the biradical is optionally in the form of a salt and is attached to the linker L through the single bonded oxygen atoms of the carboxyl groups. It also relates to a process for the preparation of the conjugates of formula (I) and to pharmaceutical compositions containing them. The conjugates of the invention are used for the treatment of cancer.
    Type: Grant
    Filed: December 15, 2009
    Date of Patent: May 5, 2015
    Assignees: Fundacio Privada Institut Catala de Nanotecnologia, Institucio Catalana de Recerca I Estudis Avancats, Universidade de Santiago de Compostela, Universitat de Valencia, Fundacio Institut de Recerca de l'Hospital de la Santa Creu J Sant Pau
    Inventors: Victor Franco Puntes, Fernando Domíguez Puente, Francisco Manuel Romero Martínez, Óscar Gallego Rubio
  • CONJUGATES COMPRISING NANOPARTICLES COATED WITH PLATINUM CONTAINING COMPOUNDS
    Publication number: 20110262500
    Abstract: The present invention relates to conjugates of formula (I) having colloidal stability in a medium, wherein NP is a gold, silver or platinum nanoparticle; L is a linker selected from the group consisting of formula (II), formula (III), and a stereoisomer of any of the formulas (II) and (III), which is attached to the nanoparticle NP through sulfur atoms; wherein the meanings of X, n, p, Y and s are further specified in the description; and A is a platinum (II) biradical selected from the group consisting of formula (IV), formula (V) and formula (VI) including any of the stereoisomers of all of them, wherein the biradical is optionally in the form of a salt and is attached to the linker L through the single bonded oxygen atoms of the carboxyl groups. It also relates to a process for the preparation of the conjugates of formula (I) and to pharmaceutical compositions containing them. The conjugates of the invention are used for the treatment of cancer.
    Type: Application
    Filed: December 15, 2009
    Publication date: October 27, 2011
    Applicants: FUNDACIÓ PRIVADA INSTITUT CATALÁ DE NANOTECNOLOGIA, INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS, FUNDACIÓ INSTITUT DE RECERCA DE L'HOSPITAL DE LA SANTA CREU I SANT PAU, UNIVERSITAT DE VALÉNCIA, UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
    Inventors: Victor Franco Puntes, Fernando Domìnguez Puente, Francisco Manuel Romero Martínez, Óscar Gallego Rubio