Abstract: Methods and apparatus for hard switching of Alternate-Arm-Converter voltage source converters. Such voltage source converters have a phase limb with a high and low side converter arm connecting an AC terminal to a high and low side DC terminal, respectively, including a chain-link circuit in series with a director switch. Each chain-link circuit includes series connected cells that can be switched to generate a controlled voltage across the chain-link circuit. In embodiments, a controller turns-off the director switch of a converter arm that is conducting current in response to a hard-switching request for a first phase limb. In response to a hard-switching request, the controller controls the chain-link circuits of the first phase limb at any point in a phase cycle to control: a DC voltage across the director switch and/or the current flowing through the director switch to a predetermined level before turning the director switch off.

Abstract: Methods and apparatus for hard switching of Alternate-Arm-Converter voltage source converters. Such voltage source converters have a phase limb with a high and low side converter arm connecting an AC terminal to a high and low side DC terminal, respectively comprising a chain-link circuit in series with a director switch. Each chain-link circuit comprises series connected cells that can be switched to generate a controlled voltage across the chain-link circuit. In embodiments, a controller turns-off the director switch of a converter arm that is conducting current in response to a hard-switching request for a first phase limb. In response to a hard-switching request, the controller controls the chain-link circuits of the first phase limb at any point in a phase cycle to control: a DC voltage across the director switch; and/or the current flowing through the director switch to a predetermined level before turning the director switch off.

Abstract: Compounds of general formula (I): where A, E, G, X, Y and the bond - - - take various meanings are of use in the preparation of a pharmaceutical formulation, for example in the treatment of a disease in which GSK-3 is involved, including Alzheimer's disease or the non-dependent insulin diabetes mellitus, or hyperproliferative disease such as cancer, displasias or metaplasias of tissue, psoriasis, arteriosclerosis or restenosis.

Abstract: Compounds of general formula (I): where A, E, G, X, Y and the bond - - - take various meanings are of use in the preparation of a pharmaceutical formulation, for example in the treatment of a disease in which GSK-3 is involved, including Alzheimer's disease or the non-dependent insulin diabetes mellitus, or hyperproliferative disease such as cancer, displasias or metaplasias of tissue, psoriasis, arteriosclerosis or restenosis.