Patents by Inventor Francisco PAN-MONTOJO

Francisco PAN-MONTOJO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230277491
    Abstract: A pharmaceutical combination is provided that includes glycolic acid or a pharmaceutically acceptable salt or ester thereof, and L-alanine and/or pyruvate, or a pharmaceutically acceptable salt thereof. A pharmaceutical combination is also provided that includes D-lactate and/or phenylbutyrate and/or tauroursodeoxycholic acid, or pharmaceutically acceptable salts or esters thereof. Methods are provided for use of the pharmaceutical combination in the treatment of neurological medical conditions, for stimulating neuronal plasticity, for regulating intracellular calcium and/or for stimulating mitochondrial function and ATP production, thereby enabling a slowing, reversing and/or inhibiting of the ageing process and/or regulating, preferably stimulating, the immune system.
    Type: Application
    Filed: July 30, 2021
    Publication date: September 7, 2023
    Inventor: Francisco PAN-MONTOJO
  • Publication number: 20220354808
    Abstract: Glycolic acid or a pharmaceutically acceptable salt or ester thereof is provided for use in the treatment or prevention of ischemic damage. In a preferred embodiment, a method for decreasing cell death caused by an ischemic insult is provided that includes contacting glycolic acid or a pharmaceutically acceptable salt or ester thereof with hypoxic tissue, in particular cortical neurons or myocardial tissue.
    Type: Application
    Filed: July 27, 2022
    Publication date: November 10, 2022
    Inventor: Francisco Pan-Montojo
  • Patent number: 11426372
    Abstract: The present invention relates to glycolic acid or a pharmaceutically acceptable salt or ester thereof for use in the treatment or prevention of ischemic damage. In a preferred embodiment the present invention relates to a method for decreasing cell death caused by an ischemic insult comprising contacting glycolic acid or a pharmaceutically acceptable salt or ester thereof with hypoxic tissue, in particular cortical neurons or myocardial tissue.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: August 30, 2022
    Inventor: Francisco Pan-Montojo
  • Patent number: 10434077
    Abstract: A method of treatment of a neurodegenerative disease which is associated with a decline in mitochondrial activity, includes administering to a person in need of such treatment at least one of Glycolic acid or a pharmaceutically acceptable salt or ester thereof, and D-lactic acid or a pharmaceutically acceptable salt or ester thereof.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: October 8, 2019
    Assignee: MAX-PLANCK-GESELLSCHAFT ZUR FĂ–RDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Teymuras Kurzchalia, Anthony A Hyman, Yusuke Toyoda, Francisco Pan-Montojo, Cihan Erkut
  • Patent number: 10182999
    Abstract: The present invention relates to glycolic acid or a pharmaceutically acceptable salt or ester thereof for use in the treatment or prevention of male infertility. The present invention also relates to an ex vivo method for increasing the mobility of spermatozoa comprising contacting glycolic acid or a pharmaceutically acceptable salt or ester thereof with spermatozoa.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: January 22, 2019
    Inventors: Francisco Pan-Montojo, Teymuras Kurzchalia, Anthony A. Hyman
  • Publication number: 20180325849
    Abstract: The present invention relates to glycolic acid or a pharmaceutically acceptable salt or ester thereof for use in the treatment or prevention of ischemic damage. In a preferred embodiment the present invention relates to a method for decreasing cell death caused by an ischemic insult comprising contacting glycolic acid or a pharmaceutically acceptable salt or ester thereof with hypoxic tissue, in particular cortical neurons or myocardial tissue.
    Type: Application
    Filed: November 17, 2016
    Publication date: November 15, 2018
    Inventor: Francisco PAN-MONTOJO
  • Publication number: 20170326085
    Abstract: A method of treatment of a neurodegenerative disease which is associated with a decline in mitochondrial activity, includes administering to a person in need of such treatment at least one of Glycolic acid or a pharmaceutically acceptable salt or ester thereof, and D-lactic acid or a pharmaceutically acceptable salt or ester thereof.
    Type: Application
    Filed: March 31, 2015
    Publication date: November 16, 2017
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: TEYMURAS KURZCHALIA, ANTHONY A HYMAN, YUSUKE TOYODA, FRANCISCO PAN-MONTOJO, CIHAN ERKUT
  • Publication number: 20170239201
    Abstract: The present invention relates to glycolic acid or a pharmaceutically acceptable salt or ester thereof for use in the treatment or prevention of male infertility. The present invention also relates to an ex vivo method for increasing the mobility of spermatozoa comprising contacting glycolic acid or a pharmaceutically acceptable salt or ester thereof with spermatozoa.
    Type: Application
    Filed: August 18, 2015
    Publication date: August 24, 2017
    Inventors: Francisco PAN-MONTOJO, Teymuras KURZCHALIA, Anthony A. HYMAN