Abstract: The described method and system allow the simultaneous detection of multicolored samples, e.g. in live cells or tissues, in a simple experimental geometry. It relies on combining ultrashort ultra-broadband laser sources (10) with a fluorescence microscope setup able to collect fluorescence intensities and/or photon arrival times per excitation volume, as well as nonlinear signals, such as second/third-harmonic and sum-frequency generation. In the description, the presented method is referred to as “SyncRGB method”.

Abstract: A vehicle wheel assembly includes a brake rotor and a wheel lock. The brake rotor has at least one of a plurality of studs and a plurality of threaded openings disposed at a rim. The brake rotor has a first lock opening that is spaced of the plurality of studs and the plurality of threaded openings. The wheel lock is received by the first lock opening when the wheel lock is installed to the brake rotor.

Abstract: A mixing device includes a mixing cavity having a partially open wall and a closed wall. In certain examples, the partially open wall and the closed wall are two separately formed pieces. A downstream side of the mixing device is shaped so as to define a helicoidal groove for circumferentially guiding gas from an outlet opening of the mixing cavity in a downstream direction. An injector sprays reactant into the mixing cavity.

Abstract: The described method and system allow the simultaneous detection of multicolored samples, e.g. in live cells or tissues, in a simple experimental geometry. It relies on combining ultrashort ultra- broadband laser sources (10) with a fluorescence microscope setup able to collect fluorescence intensities and/or photon arrival times per excitation volume, as well as nonlinear signals, such as second/third-harmonic and sum-frequency generation. In the description, the presented method is referred to as “SyncRGB method”.

Abstract: Methods of developing and using cell lines, such as stem cell lines, for therapeutic or cosmetic use. In one embodiment the cell lines are used to treat a wide range of degenerative and metabolic disorders including, but not limited to, obesity, diabetes, hypertension, and cardiac deficiency. Also described are methods of using such cell lines to screen for compounds that play a role in regulating a variety of processes.

Abstract: Adult human gonadal stem cells that are capable of differentiating into cells of the mesodermal lineage and ectodermal lineage are described.

Abstract: Methods of developing and using cell lines, such as stem cell lines, for therapeutic or cosmetic use. In one embodiment the cell lines are used to treat a wide range of degenerative and metabolic disorders including, but not limited to, obesity, diabetes, hypertension, and cardiac deficiency. Also described are methods of using such cell lines to screen for compounds that play a role in regulating a variety of processes.

Abstract: The disclosure provides compositions and methods useful for treating injuries to the central nervous system (e.g., spinal cord injuries). The compositions and methods described herein can be optionally used in combination with a variety of techniques (e.g., surgical techniques) and/or therapies (e.g., physical therapy regimens) to affect treatment of injuries to the central nervous system.

Abstract: Industrial plasma reactor for plasma assisted thermal debinding of power injection-molded parts is a reactor used for the plasma assisted debinding and sintering of metallic or ceramic parts produced by the powder injection molding process, comprising a vacuum chamber (1) containing a cathode-anode (7,8) system for plasma generation and a resistive heating system (6) in the same vacuum chamber (1) ambient

Abstract: Methods for therapeutically programming human adult stem cells into pluripotent cells are provided. Cell therapeutically programmed from adult testicular cells are disclosed. The therapeutically reprogrammed cells are suitable for cellular regenerative therapy and have the potential to differentiate into more committed cell lineages.

Abstract: A scooter has a frame including a footrest, the footrest having a front edge. Two or more ground engaging rear wheels are connected to the frame and configured to support the frame. A ground engaging front wheel is connected to the frame and mounted for rotation about a vertical axis so that the front wheel is a steerable wheel, the front wheel having a center line. The center line of the front wheel is positioned rearward of the front edge of the footrest and forward of the rear wheels. A drive motor is connected to either the front wheel or the rear wheels, the drive motor being configured to drive the scooter. A steering mechanism is connected to the front wheel and configured to steer the front wheel.

Abstract: A personal mobility vehicle includes a frame, a ground engaging front wheel connected to the frame and mounted for rotation about a substantially, vertical axis so the front wheel is a steerable wheel, and a drive motor connected to either the front wheel or the rear wheels, the drive motor being configured to drive the scooter. Two or more ground engaging rear wheels are connected to the frame and configured to support the frame. A tiller assembly is connected to the frame and configured to allow the vehicle user to steer the front wheel. A steering hub is connected to the frame and configured to rotatably support the tiller assembly, wherein the steering hub is forward of and spaced apart from the front wheel.

Abstract: Pluripotent therapeutically programmed cells and methods for making such cells are provided. The pluripotent therapeutically programmed cells are post-natal stem cells which have been matured such that they represent either a more differentiated state or a less differentiated state after contact with stimulatory factors. The pluripotent therapeutically reprogrammed cells are suitable for cellular regenerative therapy and have the potential to differentiate into more committed cell lineages. Also disclosed are culture media for therapeutically reprogramming post-natal stem cells.

Abstract: Methods are provided for therapeutically reprogramming differentiated cells with nuclear extracts from pluripotent stem cells to generate a pluripotent epigenetic state in the differentiated cells. Additionally, therapeutically programmed cells for therapeutic use in patients are provided. Therapeutically programmed cells are stem cells which have been matured such that they represent either a more differentiated state or a less differentiated state after contact with stimulatory factors.

Abstract: Compositions and methods for promoting tissue regeneration, particularly skin regeneration, with adipose-derived stem cells are provided. Additionally methods and compositions for promoting tissue regeneration with adipose-derived stem cell side population cells are provided. The adipose-derived cells are administered in a tissue regenerating effect amount optionally with a bioactive agent. Additionally the adipose derived cells can be autologous or syngeneic.

Abstract: Therapeutically programmed cells and methods for making such cells are provided. Therapeutically programmed cells are stem cells which have been matured such that they represent either a more differentiated state or a less differentiated state after contact with stimulatory factors. The therapeutically reprogrammed cells are suitable for cellular regenerative therapy and have the potential to differentiate into more committed cell lineages. Additionally, hybrid stem cells suitable for therapeutic reprogramming and cellular regenerative therapy are provided.