Patents by Inventor Franciscus Gerardus Spee

Franciscus Gerardus Spee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Devices for separating, mixing and concentrating magnetic particles with a fluid
    Patent number: 8187460
    Abstract: The present invention is related to devices for manipulating magnetic particles that are suspended in a fluid, possibly containing a biological entity of interest, the magnetic particles being able to bind the entity of interest, the fluid being contained in a reaction vessel constituted by a large upper compartment with a funnel shape, an elongate lower compartment with a substantially constant cross-section and a closed base. The devices are especially useful in methods for the extraction of nucleic acid to enable them for further processing.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: May 29, 2012
    Assignee: BioMerieux, B.V.
    Inventors: Hermannus Johannes Maria Kreuwel, Emiel Gerebern Maria Verwimp, Bernardus Jozef Maria Beerling, Franciscus Gerardus Spee
  • DEVICES FOR SEPARATING, MIXING AND CONCENTRATING MAGNETIC PARTICLES WITH A FLUID
    Publication number: 20110220567
    Abstract: The present invention is related to devices for manipulating magnetic particles that are suspended in a fluid, possibly containing a biological entity of interest, the magnetic particles being able to bind the entity of interest, the fluid being contained in a reaction vessel constituted by a large upper compartment with a funnel shape, an elongate lower compartment with a substantially constant cross-section and a closed base. The devices are especially useful in methods for the extraction of nucleic acid to enable them for further processing.
    Type: Application
    Filed: May 26, 2011
    Publication date: September 15, 2011
    Inventors: Hermannus Johannes Maria Kreuwel, Emiel Gerebern Maria Verwimp, Bernardus Jozef Maria Beerling, Franciscus Gerardus Spee
  • Device and method for separating, mixing and concentrating magnetic particles with a fluid and use thereof in purification methods
    Patent number: 7972516
    Abstract: A process for manipulating magnetic particles suspended in a fluid that are able to bind to an entity of interest, the fluid being contained in a reaction vessel having a large funnel shaped upper compartment, an elongate lower compartment of substantially constant cross-section and a closed base. The process consists of: a) subjecting the magnetic particles to two simultaneously applied magnetic fields to separate all said magnetic particles present in at least the upper compartment of the vessel from the fluid, b) transferring the separated magnetic particles from the upper compartment to the lower compartment, c) removing the fluid from the vessel, d) adding a washing liquid to the lower compartment, e) subjecting the magnetic particles to at least two magnetic fields applied successively with changing directions to wash all the magnetic particles present in the lower compartment, and concentrating said magnetic particles in said lower compartment.
    Type: Grant
    Filed: July 22, 2005
    Date of Patent: July 5, 2011
    Assignee: Biomerieux, B.V.
    Inventors: Hermannus Johannes Maria Kreuwel, Emiel Gerebern Maria Verwimp, Bernardus Jozef Maria Beerling, Franciscus Gerardus Spee