Patents by Inventor Franciscus Petrus Nijkamp

Franciscus Petrus Nijkamp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound for inhibiting the influx of polymorphonuclear leukocytes (PMNs) in a tissue, its selection, pharmaceutical compositions and use
    Patent number: 7410806
    Abstract: The invention relates to a compound suitable for inhibiting the influx of polymorphonuclear leukocytes (PMNs) into a tissue involved in a chronic inflammatory disease. The compound according to the invention is capable of forming a complex with N-acetyl-Pro-Gly-Pro. The invention also relates to a method of selecting such a compound, a pharmaceutical composition and an application of the compound.
    Type: Grant
    Filed: August 22, 2005
    Date of Patent: August 12, 2008
    Assignee: Fornix Biosciences N.V.
    Inventors: Franciscus Petrus Nijkamp, Rosswell Robert Pfister, Jeffrey Lynn Haddox, James Edwin Blalock, Matteo Villain
  • Inhibition of protein binding to mast cells
    Patent number: 7056511
    Abstract: The invention relates to a compound inhibiting the binding of the free light chain of immunoglobulin (Ig LC) to mast cells. It has been found that Ig LC is the agent responsible for the sensitization of mast cells. The compounds according to the invention can thus be used for the preparation of a drug for the treatment of a disease whose symptom is an elevated Ig LC concentration in serum or spinal fluid. The invention also relates to a method of screening a series of compounds on their ability to reduce the sensitization of mast cells.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: June 6, 2006
    Assignee: Fornix Biosciences N.V.
    Inventors: Franciscus Antonius M. Redegeld, Aletta Desireé Kraneveld, Franciscus Petrus Nijkamp
  • Compound for inhibiting the influx of polymorphonuclear leukocytes (PMNS) in a tissue, its selection, pharmaceutical compositions and use
    Patent number: 6960565
    Abstract: The invention relates to a compound suitable for inhibiting the influx of polymorphonuclear leukocytes (PMNs) into a tissue involved in a chronic inflammatory disease. The compound according to the invention is capable of forming a complex with N-acetyl-Pro-Gly-Pro. The invention also relates to a method of selecting such a compound, a pharmaceutical composition and an application of the compound.
    Type: Grant
    Filed: November 13, 2003
    Date of Patent: November 1, 2005
    Assignee: Fornix Biosciences N.V.
    Inventors: Franciscus Petrus Nijkamp, Rosswell Robert Pfister, Jeffrey Lynn Haddox, James Edwin Blalock, Matteo Villain
  • Compound for inhibiting the influx of polymorphonuclear leukocytes (PMNS) in a tissue, its selection, pharmaceutical compositions and use
    Publication number: 20040176304
    Abstract: The invention relates to a compound suitable for inhibiting the influx of polymorphonuclear leukocytes (PMNs) into a tissue involved in a chronic inflammatory disease. The compound according to the invention is capable of forming a complex with N-acetyl-Pro-Gly-Pro. The invention also relates to a method of selecting such a compound, a pharmaceutical composition and an application of the compound.
    Type: Application
    Filed: November 13, 2003
    Publication date: September 9, 2004
    Inventors: Franciscus Petrus Nijkamp, Rosswell Robert Pfister, Jeffrey Lynn Haddox, James Edwin Blalock, Matteo Villain
  • Inhibition of protein binding to mast cells
    Publication number: 20020045186
    Abstract: The invention relates to a compound inhibiting the binding of the free light chain of immunoglobin (Ig LC) to mast cells. It has been found that Ig LC is the agent responsible for the sensitization of mast cells. The compounds according to the invention can thus be used for the preparation of a drug for the treatment of a disease whose symptom is an elevated Ig LC concentration in serum or spinal fluid. The invention also relates to a method of screening a series of compounds on their ability to reduce the sensitization of mast cells.
    Type: Application
    Filed: January 9, 2001
    Publication date: April 18, 2002
    Inventors: Franciscus Antonius, M. Redegeld, Aletta Desiree Kraneveld, Franciscus Petrus Nijkamp