Patents by Inventor Franciscus Theodorus Leonardus Brands

Franciscus Theodorus Leonardus Brands has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • (11beta, 17alpha)-11-(4-(2-11C-ACETYL)PHENYL)-17,23-EPOXY-19,24-DINORCHOLA-4,9,20-TRIEN-3-ONE
    Publication number: 20130272956
    Abstract: The present invention relates to (11?,17?)-11-(4-(2-11C-acetyl)phenyl)-17,23-epoxy-19,24-dinorchola-4,9,20-trien-3-one, an 11C-labelled ORG 33628; a process for the preparation thereof, intermediates used in this process and the use of this compound as a PET tracer for the detection of breast cancer.
    Type: Application
    Filed: June 17, 2011
    Publication date: October 17, 2013
    Inventors: Franciscus Theodorus Leonardus Brands, Johannes Antonius Maria Hamersma, Peter Hermanus Gerardus Wiegerinck
  • Method for the preparation of steroid derivative ketal
    Patent number: 6005124
    Abstract: The invention relates to a method for the preparation of a steroid derivative ketal of formula I: ##STR1## characterized in that a compound of formula II: ##STR2## is treated with an alcohol in the presence of an orthoester, wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined by the specification.
    Type: Grant
    Filed: January 4, 1999
    Date of Patent: December 21, 1999
    Assignee: Akzo Nobel, N.V.
    Inventors: Franciscus Theodorus Leonardus Brands, Pieter Vrijhof
  • Method for the preparation of steroid derivative ketal
    Patent number: 5955622
    Abstract: The invention relates to a method for the preparation of a compound of formula II: ##STR1## wherein a compound of formula V: ##STR2## is condensed with a compound of the formula CH.sub.3 -C(OR.sub.4 O)-(CH.sub.2).sub.3 -XHal and R.sub.1, R.sub.2, R.sub.3, R.sub.4, X and Hal are as defined by the specification.
    Type: Grant
    Filed: August 5, 1998
    Date of Patent: September 21, 1999
    Assignee: Akzo Nobel, N.V.
    Inventors: Franciscus Theodorus Leonardus Brands, Pieter Vrijhof