Patents by Inventor Franck DOERFLINGER

Franck DOERFLINGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF CK8 POSITIVE CANCERS IN RELATION WITH K-RAS GENE STATUS
    Publication number: 20230062308
    Abstract: The invention relates to the use of an anti-CK8 antibody alone or in combination therapy (with another antibody and/or chemotherapeutic agent) to (1) treat solid tumours expressing CK8 having wild-type K-Ras (not mutated as disclosed herein) and (2) treat solid tumours expressing CK8 having K-Ras mutation as disclosed herein. The invention also relates to the use of anti-CK8 antibodies having internalizing property, allowing to deliver cytotoxic agent coupled to antibody for the treatment of CK8 positive solid tumours, having wild-type K-Ras (not mutated as disclosed herein) or having K-Ras mutation as disclosed herein.
    Type: Application
    Filed: September 29, 2022
    Publication date: March 2, 2023
    Inventors: Claudine Brigitte Fernande VERMOT-DESCROCHES, Emilie LAVOCAT, Franck DOERFLINGER
  • TREATMENT OF CK8 POSITIVE CANCERS IN RELATION WITH K-RAS GENE STATUS
    Publication number: 20200255506
    Abstract: The invention relates to the use of an anti-CK8 antibody alone or in combination therapy (with another antibody and/or chemotherapeutic agent) to (1) treat solid tumours expressing CK8 having wild-type K-Ras (not mutated as disclosed herein) and (2) treat solid tumours expressing CK8 having K-Ras mutation as disclosed herein. The invention also relates to the use of anti-CK8 antibodies having internalizing property, allowing to deliver cytotoxic agent coupled to antibody for the treatment of CK8 positive solid tumours, having wild-type K-Ras (not mutated as disclosed herein) or having K-Ras mutation as disclosed herein.
    Type: Application
    Filed: August 17, 2018
    Publication date: August 13, 2020
    Inventors: Claudine Brigitte Fernande VERMOT-DESCROCHES, Emilie LAVOCAT, Franck DOERFLINGER