Abstract: Provided are sequestering agents for sequestering non-water moieties from an aqueous solution. The sequestering agents may comprise a detergent; and a polymer operable to stabilize formation of a detergent micelle thereby causing the detergent and polymer to self-assemble into a nanonet upon exposure to the aqueous solution. Also provided are kits therefore and methods for use of the sequestering agents and kits.

Abstract: Provided are sequestering agents for sequestering non-water moieties from an aqueous solution. The sequestering agents may comprise a detergent; and a polymer operable to stabilize formation of a detergent micelle thereby causing the detergent and polymer to self-assemble into a nanonet upon exposure to the aqueous solution. Also provided are kits therefore and methods for use of the sequestering agents and kits.

Abstract: Scaffold peptides and methods of making and using same. The scaffold peptides have a general structure from the N-terminus to the C-terminus, AH1-linker-AH2. AH1 and AH2 each comprise an alpha helical structure and may fold against each other about the linker to form a bi-helical structure. The scaffold peptide includes alternating polar and non-polar regions. The non-polar regions of the scaffold peptide interact with the hydrophobic regions of the proteins to solubilize same in aqueous solutions without the presence of detergent. In some embodiments, the scaffold peptides are used for hydrophobic protein purification, isolation and/or stabilization.

Abstract: Provided are sequestering agents for sequestering non-water moieties from an aqueous solution. The sequestering agents may comprise a detergent; and a polymer operable to stabilize formation of a detergent micelle thereby causing the detergent and polymer to self-assemble into a nanonet upon exposure to the aqueous solution. Also provided are kits therefore and methods for use of the sequestering agents and kits.