Patents by Inventor Franck Kalume

Franck Kalume has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ARTIFICIAL EXPRESSION CONSTRUCTS FOR SELECTIVELY MODULATING GENE EXPRESSION IN INTERNEURONS
    Publication number: 20210348195
    Abstract: Artificial expression constructs for selectively modulating gene expression in selected central nervous system cell types are described. The artificial expression constructs can be used to selectively express synthetic genes or modify gene expression in GABAergic interneurons.
    Type: Application
    Filed: October 3, 2019
    Publication date: November 11, 2021
    Applicants: Allen Institute, Seattle Children's Hospital d/b/a Seattle Children's Research Institute
    Inventors: Jonathan Ting, Boaz P. Levi, John K. Mich, Edward Sebastian Lein, Franck Kalume
  • RESCUING VOLTAGE-GATED SODIUM CHANNEL FUNCTION IN INHIBITORY NEURONS
    Publication number: 20210015898
    Abstract: Selectively providing voltage-gated sodium channel function sufficient to rescue impaired Nav1.1 function to inhibitory neurons is described. Provided voltage-gated sodium channel function sufficient to rescue impaired Nav1.1 function in inhibitory neurons can be used to treat disorders such as epilepsy, and more particularly, Dravet Syndrome.
    Type: Application
    Filed: April 9, 2019
    Publication date: January 21, 2021
    Applicants: ALLEN INSTITUTE, SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE
    Inventors: John K. Mich, Edward Sebastian Lein, Jonathan Ting, Boaz P. Levi, Erik Hess, Franck Kalume