Patents by Inventor Franck Mallet

Franck Mallet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Siremadlin Succinate
    Publication number: 20220175682
    Abstract: The present invention relates to methods of preparing pharmaceutical products, involving filling active pharmaceutical ingredient powders into pharmaceutical carriers with a vacuum assisted metering and filling device. The methods disclosed herein can be used in a continuous process, such as in a high-throughput process for producing a pharmaceutical product. The present invention further relates to a particular quality of the neat active pharmaceutical ingredient (API) HDM201, i.e. siremadlin, present as succinic acid co-crystal, which can be used in the methods of preparation of the present invention.
    Type: Application
    Filed: April 2, 2020
    Publication date: June 9, 2022
    Inventors: Nicole BIERI, Elodia DI RENZO, David HOOK, Jennifer Claire HOOTON, Markus KRUMME, Steffen LANG, Franck MALLET, Massimo MORATTO, Joerg OGORKA, Jim PARKS, Dale W. PLOEGER, Norbert RASENACK, Hendrik SCHNEIDER, Lipa SHAH, Stefan STEIGMILLER, Gordon STOUT, Patrick TRITSCHLER, Fabian WEBER
  • Chemical Process for Preparing Imidazopyrrolidinone Derivatives and Intermediates Thereof
    Publication number: 20210087194
    Abstract: The present disclosure relates to a method of synthesizing imidazopyrrolidinone derivative, such as compound of formula (I), or a solvate including hydrate thereof, or a co-crystal thereof, and/or intermediates thereof, their use as pharmaceuticals and the use of intermediates.
    Type: Application
    Filed: September 1, 2020
    Publication date: March 25, 2021
    Inventors: Hao Wang, Jiong Ye, Bo Han, Dietmar Flubacher, Hans Stettler, Fabrice Gallou, Franck Mallet, Matthias Napp, Michael Haller
  • Chemical Process for Preparing Imidazopyrrolidinone Derivatives and Intermediates Thereof
    Publication number: 20190337952
    Abstract: The present disclosure relates to a method of synthesizing imidazopyrrolidi-none derivative, such as compound of formula (I), or a solvate including hydrate thereof, or a co-crystal thereof, and/or intermediates thereof, their use as pharmaceuticals and the use of intermediates.
    Type: Application
    Filed: November 20, 2017
    Publication date: November 7, 2019
    Inventors: Hao Wang, Jiong Ye, Bo Han, Dietmar Flubacher, Hans Stettler, Fabrice Gallou, Franck Mallet, Matthias Napp, Michael Haller
  • Particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide
    Patent number: 9802917
    Abstract: The present invention relates to particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide, to a process of making said particles, to pharmaceutical compositions comprising said particles and to method of treating cancers using said pharmaceutical compositions.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: October 31, 2017
    Assignee: Novartis AG
    Inventors: Nicole Buschmann, Robin Alec Fairhurst, Pascal Furet, Bo Han, Thomas Knöpfel, Catherine Leblanc, Lv Liao, Robert Mah, Franck Mallet, Julie Martz, Can Wang, Jing Xiong, Xianglin Zhao
  • Particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide
    Publication number: 20160304489
    Abstract: The present invention relates to particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide, to a process of making said particles, to pharmaceutical compositions comprising said particles and to method of treating cancers using said pharmaceutical compositions.
    Type: Application
    Filed: March 18, 2016
    Publication date: October 20, 2016
    Applicant: NOVARTIS AG
    Inventors: Nicole BUSCHMANN, Robin Alec FAIRHURST, Pascal FURET, Bo HAN, Thomas KNÖPFEL, Catherine LEBLANC, Lv LIAO, Robert MAH, Franck MALLET, Julie MARTZ, Can WANG, Jing XIONG, Xianglin ZHAO
  • Modafinil polymorphic forms
    Patent number: 7649020
    Abstract: Polymorphic forms of modafinil racemate, methods of preparation thereof, pharmaceutical compositions and methods of therapeutic treatment involving modafinil polymorphic forms.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: January 19, 2010
    Assignee: Cephalon France
    Inventors: Michel Broquaire, Véronique Broquaire, legal representative, Laurent Courvoisier, Armand Frydman, Gerard Coquerel, Franck Mallet
  • Modafinil polymorphic forms
    Patent number: 7405323
    Abstract: Modafinil polymorphic forms of modafinil racemate, methods of preparation thereof, pharmaceutical compositions and methods of therapeutic treatment involving modafinil polymorphic forms.
    Type: Grant
    Filed: October 12, 2005
    Date of Patent: July 29, 2008
    Assignee: Cephalon France
    Inventors: Véronique Broquaire, legal representative, Ludovic Broquaire, legal representative, Laurent Courvoisier, Gerard Coquerel, Franck Mallet, Michel Broquaire
  • Modafinil Polymorphic Forms
    Publication number: 20080153918
    Abstract: Polymorphic forms of modafinil racemate, methods of preparation thereof, pharmaceutical compositions and methods of therapeutic treatment involving modafinil polymorphic forms.
    Type: Application
    Filed: December 14, 2007
    Publication date: June 26, 2008
    Applicant: Cephalon France
    Inventors: Michel Broquaire, Veronique Broquaire, Laurent Courvoisier, Armand Frydman, Gerard Coquerel, Franck Mallet
  • Modafinil polymorphic forms
    Publication number: 20060252835
    Abstract: Modafinil polymorphic forms of modafinil racemate, methods of preparation thereof, pharmaceutical compositions and methods of therapeutic treatment involving modafinil polymorphic forms.
    Type: Application
    Filed: October 12, 2005
    Publication date: November 9, 2006
    Applicants: Cephalon France, Organisation De Synthese Mondiale Orsymonde
    Inventors: Michel Broquaire, Veronique Broquaire, Ludovic Broquaire, Laurent Courvoisier, Armand Frydman, Gerard Coquerel, Franck Mallet
  • Process for the preparation of and crystalline forms of optical enantiomers of modafinil
    Publication number: 20060241320
    Abstract: The invention relates to a process for the preparation of crystalline forms of the optical enantiomers of modafinil, comprising stages comprising: i) dissolving one of the optical enantiomers of modafinil in a solvent other than ethanol, ii) crystallising the modafinil enantiomer, iii) recovering the crystalline form of the modafinil enantiomer so obtained. The invention also relates to a process for the preparation of the optical enantiomers of modafinil.
    Type: Application
    Filed: June 26, 2006
    Publication date: October 26, 2006
    Applicants: Cephalon France, Organisation De Synthese Mondiale Orsymonde
    Inventors: Olivier Neckebrock, Laurent Courvoisier, Stephanie Graf, Gilles Serrure, Gerard Francois Coquerel, Sebastien Rose, Christine Besselievre, Franck Mallet, Adriaan Van Langevelde
  • Method for the production of crystalline forms and crystalline forms of optical enantiomers of modafinil
    Publication number: 20060135621
    Abstract: The invention relates to a process for the preparation of crystalline forms of the optical enantiomers of modafinil, comprising stages comprising: i) dissolving one of the optical enantiomers of modafinil in a solvent other than ethanol, ii) crystallising the modafinil enantiomer, iii) recovering the crystalline form of the modafinil enantiomer so obtained. The invention also relates to a process for the preparation of the optical enantiomers of modafinil.
    Type: Application
    Filed: December 18, 2003
    Publication date: June 22, 2006
    Applicants: Cephalon France, Organisation De Synthese Mondiale Orsymonde
    Inventors: Olivier Neckebrock, Laurent Courvoisier, Stephanie Graf, Gilles Serrure, Gerard Coquerel, Sebastien Rose, Christine Besselievre, Franck Mallet, Adriaan Van Langevelde
  • Modafinil polymorphic forms
    Patent number: 6992219
    Abstract: Modafinil polymorphic forms of modafinil racemate, methods of preparation thereof, pharmaceutical compositions and methods of therapeutic treatment involving modafinil polymorphic forms.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: January 31, 2006
    Assignees: Cephalon France, Organisation de Synthese Mondiale Orsymonde
    Inventors: Véronique Broquaire, legal representative, Ludovic Broquaire, legal representative, Laurent Courvoisier, Armand Frydman, Gerard Coquerel, Franck Mallet, Michel Broquaire, deceased
  • Modafinil polymorphic forms
    Publication number: 20040102523
    Abstract: Modafinil polymorphic forms of modafinil racemate, methods of preparation thereof, pharmaceutical compositions and methods of therapeutic treatment involving modafinil polymorphic forms.
    Type: Application
    Filed: August 7, 2003
    Publication date: May 27, 2004
    Inventors: Michel Broquaire, Laurent Courvoisier, Armand Frydman, Gerard Coquerel, Franck Mallet, Veronique Broquaire, Ludovic Broquaire