Patents by Inventor Franck Morel

Franck Morel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for increasing the expression of anti-microbial peptides by keratinocytes comprising administering a composition comprising IL-17, TNF-alpha and OSM
    Patent number: 10080779
    Abstract: The invention disclosed herein relates to the field of epidermal repair and skin innate immunity. More particularly, the invention concerns the use of a mix of cytokines to inhibit keratinocyte differentiation, activate skin innate immunity, increase the expression of anti-microbial peptides, and improve epidermal repair. In particular, the invention concerns compositions comprising at least IL-17, TNF? and OSM that can be formulated for topical administration for cosmetic or dermatologic use.
    Type: Grant
    Filed: September 29, 2014
    Date of Patent: September 25, 2018
    Assignees: Universite D'Angers, Universite de Poitiers, Bioalternatives SAS
    Inventors: Jean-Claude Lecron, Hughes Gascan, Franck Morel, Sylvie Chevalier, Francois-Xavier Bernard, Katia Boniface, Caroline Diveau
  • COMPOSITIONS AND METHODS FOR ENHANCING EPIDERMAL REPAIR AND CUTANEOUS INNATE IMMUNITY
    Publication number: 20150086508
    Abstract: The invention disclosed herein relates to the field of epidermal repair and skin innate immunity. More particularly, the invention concerns the use of a mix of cytokines to inhibit keratinocyte differentiation, activate skin innate immunity, increase the expression of anti-microbial peptides, and improve epidermal repair. In particular, the invention concerns compositions comprising at least IL-17, TNF? and OSM that can be formulated for topical administration for cosmetic or dermatologic use.
    Type: Application
    Filed: September 29, 2014
    Publication date: March 26, 2015
    Inventors: Jean-Claude Lecron, Hughes Gascan, Franck Morel, Sylvie Chevalier, Francois-Xavier Bernard, Katia Boniface, Caroline Diveau
  • COMPOSITIONS FOR PREVENTING, REDUCING OR TREATING KERATINOCYTE-MEDIATED INFLAMMATION
    Publication number: 20120142755
    Abstract: The present invention relates to the field of epidermal repair. More particularly, the invention concerns the use of a molecule able to inhibit a heteromeric receptor comprising OSMR? as a subunit, for the preparation of a composition for inhibiting the expression of inflammatory factors by the keratinocytes. In particular, the invention concerns the use of antagonists and/or expression inhibitors of OSM, IL-17, TNF?, IL-31, IFN-?, and/or the OSMR? subunit, for the preparation of cosmetic or dermatologic compositions, especially for treating inflammatory skin diseases. Methods for obtaining in vitro or animal models of skin inflammation diseases are also disclosed. These models can be used for screening molecules to find new drugs to prevent or treat psoriasis and other dermatitis.
    Type: Application
    Filed: October 27, 2011
    Publication date: June 7, 2012
    Applicants: UNIVERSITE D'ANGERS, BIOALTERNATIVES SAS, UNIVERSITE DE POITIERS
    Inventors: Jean-Claude Lecron, Hughes Gascan, Franck Morel, Sylvie Chevalier, François-Xavier Bernard, Katia Boniface, Caroline Diveu
  • Compositions for enhancing keratinocyte migration and epidermal repair via a receptor containing OSMR? as a subunit, and applications thereof
    Patent number: 7901669
    Abstract: The present invention relates to the field of epidermal repair. More particularly, the invention concerns the use of a molecule able to activate a heteromeric receptor comprising OSMR? as a subunit, for the preparation of a composition for activating in vitro and/or in vivo keratinocyte migration and/or the expression of anti-microbial peptides by the keratinocytes. In particular, the invention concerns the use of OSM and/or IL-17 and/or TNF? and/or IL-31, or agonists thereof, for the preparation of cosmetic or dermatologic compositions.
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: March 8, 2011
    Assignees: Universite d'Angers, Universite de Poitiers, Bioalternatives SAS
    Inventors: Jean-Claude Lecron, Hughes Gascan, Franck Morel, Sylvie Chevalier, François-Xavier Bernard, Katia Boniface, Caroline Diveu
  • COMPOSITIONS FOR PREVENTING, REDUCING OR TREATING KERATINOCYTE-MEDIATED INFLAMMATION
    Publication number: 20090300776
    Abstract: The present invention relates to the field of epidermal repair. More particularly, the invention concerns the use of a molecule able to inhibit a heteromeric receptor comprising OSMR? as a subunit, for the preparation of a composition for inhibiting the expression of inflammatory factors by the keratinocytes. In particular, the invention concerns the use of antagonists and/or expression inhibitors of OSM, IL-17, TNF?, IL-31, IFN-?, and/or the OSMR? subunit, for the preparation of cosmetic or dermatologic compositions, especially for treating inflammatory skin diseases. Methods for obtaining in vitro or animal models of skin inflammation diseases are also disclosed. These models can be used for screening molecules to find new drugs to prevent or treat psoriasis and other dermatitis.
    Type: Application
    Filed: December 15, 2005
    Publication date: December 3, 2009
    Applicants: UNIVERSITE D'ANGERS, UNIVERSITE DE POITIERS, BIOALTERNATIVES SAS
    Inventors: Jean-Claude Lecron, Hughes Gascan, Franck Morel, Sylvie Chevalier, Francois-Xavier Bernard, Katia Boniface, Caroline Diveu
  • COMPOSITIONS FOR ENHANCING KERATINOCYTE MIGRATION AND EPIDERMAL REPAIR VIA A RECEPTOR CONTAINING OSMRBETA AS A SUBUNIT, AND APPLICATIONS THEREOF
    Publication number: 20090104146
    Abstract: The present invention relates to the field of epidermal repair. More particularly, the invention concerns the use of a molecule able to activate a heteromeric receptor comprising OSMR? as a subunit, for the preparation of a composition for activating in vitro and/or in vivo keratinocyte migration and/or the expression of anti-microbial peptides by the keratinocytes. In particular, the invention concerns the use of OSM and/or IL-17 and/or TNF? and/or IL-31, or agonists thereof, for the preparation of cosmetic or dermatologic compositions.
    Type: Application
    Filed: December 15, 2005
    Publication date: April 23, 2009
    Inventors: Jean-Claude Lecron, Hughes Gascan, Franck Morel, Sylvie Chevalier, Francois-Xavier Bernard, Katia Boniface, Caroline Diveu