Abstract: The present invention involves compositions for use as granular bone replacements. The compositions of the present invention are comprised of hyaluronic acid esters or salts of hyaluronic acid in association with a pharmacologically active compound wherein the molecular weight of the hyaluronic acid is below 250,000 and either artificial or natural bone granules. The present invention further involves a method of promoting the growth or repair of damaged or defective bones in either humans or animals using the compositions of hyaluronic acid derivatives and bone granules.

Abstract: The present invention involves compositions for use as granular bone replacements. The compositions of the present invention are comprised of hyaluronic acid esters or salts of hyaluronic acid in association with a pharmacologically active compound wherein the molecular weight of the hyaluronic acid is below 250,000 and either artificial or natural bone granules. The present invention further involves a method of promoting the growth or repair of damaged or defective bones in either humans or animals using the compositions of hyaluronic acid derivatives and bone granules.

Abstract: The present invention is drawn to medical devices comprising biodegradable guide channels for use in the repair and regeneration of nerve tissue. The guide channels of the present invention comprise interlaced threads imbedded in a matrix, wherein both the matrix and the threads comprise biocompatible and bioabsorbable esters of hyaluronic acid. The matrix of the present invention further optionally comprises biologically or pharmacologically active factors in association with the guide channels.

Abstract: Biomaterials are disclosed comprised of biodegradable, biocompatible, and bioabsorbable non-woven fabric materials for use in surgery for the guided regeneration of tissues. The non-woven fabric materials constitute threads embedded in a matrix, wherein both the matrix and the threads constitute auto-crosslinked hyaluronic acid.

Abstract: Provided is a multilayered of nonwoven material comprising a surface layer which comes into contact with the skin, and one or more other layers which do not come into contact with the skin, wherein said surface layer which comes into contact with the skin is a member selected from the group consisting of a surface layer comprising at least one hyaluronic acid ester, a surface layer comprising a mixture of said at least one hyaluronic acid ester and at least one natural polymer, semisynthetic polymer, or synthetic polymer, and a surface layer comprising a natural, synthetic, or semisynthetic biocompatible perforated membrane compatible with cell growth on its surface. This material can be employed in a wide variety of medical and sanitary applications, including surgery and as a non-adhesive covering material.

Abstract: Biomaterials are disclosed comprised of biodegradable, biocompatible, and bioabsorbable composite membranes for use in surgery for the guided regeneration of tissues. The composite membranes are comprised of threads embedded in a matrix, wherein both the matrix and the threads can be comprised of esters of hyaluronic acid, used singly or in combination, or esters of hyaluronic acid in combination with esters of alginic acid or other polymers.

Abstract: Biomaterials are disclosed comprised of biodegradable, biocompatible, and bioabsorbable nonwoven fabric materials for use in surgery for the guided regeneration of tissues. The non-woven fabric materials are comprised of threads embedded in a matrix, wherein both the matrix and the threads can be comprised of esters of hyaluronic acid, used singly or in combination, or esters of hyaluronic acid in combination with esters of alginic acid or other polymers.