Patents by Inventor Franco Faustini

Franco Faustini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6-Alkylidene 10 .beta.-alkynylestrene derivatives and pharmaceutical methods for their use
    Patent number: 4808578
    Abstract: The invention relates to 6-substituted 10.beta.-alkynylestrene derivatives wherein the 6 substituent is amino, azido, halogen or an alkylidene group and to corresponding 6,7-dihalo analogs.The invention provides also a process for the preparation of the above compounds and pharmaceutical compositions containing same.The compounds of the invention are useful aromatase inhibitors and can be used, e.g., in the treatment of hormone-dependent tumors and prostatic hyperplasia.
    Type: Grant
    Filed: December 15, 1986
    Date of Patent: February 28, 1989
    Assignee: Farmitalia Carlo Erba S. R. L.
    Inventors: Franco Faustini, Enrico di Salle, Vittoria Villa, Paolo Lombardi
  • Steroidic aromatase inhibitors
    Patent number: 4771043
    Abstract: The invention relates to 6-substituted androsta-1,4-diene-3,17-dione derivatives wherein the 6 substituent is an azido, amino or substituted amino group.The invention provides also a process for preparing the said compounds and pharmaceutical compositions containing same.The compounds of the invention are useful aromatase inhibitors and can be used, e.g., in the treatment of hormone-dependent tumors.
    Type: Grant
    Filed: July 21, 1986
    Date of Patent: September 13, 1988
    Assignee: Farmitalia Carlo Erba, S.p.A.
    Inventors: Franco Faustini, Roberto D'Alessio, Vittoria Villa, Enrico di Salle, Paolo Lombardi
  • 4-amino androstendione derivatives and process for their preparation
    Patent number: 4757061
    Abstract: The invention discloses 4-substituted androstendione derivatives of the following formula (I) ##STR1## wherein R is amino or substituted amino or azido,one of R.sub.1 and R.sub.2 is hydrogen and the other is hydrogen, alkyl, alkenyl or alkynyl, and(x) and (y) are each, independently, a single bond or a double bond.The compounds of formula (I) are useful aromatase inhibitors.
    Type: Grant
    Filed: February 10, 1986
    Date of Patent: July 12, 1988
    Assignee: Farmitalia Carlo Erba, S.p.A.
    Inventors: Franco Faustini, Roberto D'Alessio, Vittoria Villa, Enrico di Salle, Paolo Lombardi
  • 16-fluoro-16,17-didehydro prostanoids and process for their preparation
    Patent number: 4626597
    Abstract: 16-Fluoro-16,17-didehydro prostanoids, processes for their preparation, compositions containing them and methods of using them are disclosed. The compounds and compositions have pharmaceutical utility including, for example, luteolytic activity.
    Type: Grant
    Filed: August 22, 1984
    Date of Patent: December 2, 1986
    Assignee: Farmitalia Carlo Erba, S.p.A.
    Inventors: Franco Faustini, Roberto d'Alessio, Achille Panzeri, Enrico di Salle
  • Furyl derivatives of 16-substituted prostaglandins
    Patent number: 4585791
    Abstract: The present invention relates to new furyl derivatives of 16-substituted prostaglandins, to a process for their preparation and to pharmaceutical and veterinary compositions containing them.The new compounds of the invention are optically active or racemic prostaglandins of the following formula (I) ##STR1## wherein R is(1) --OH or --OR' wherein R' is C.sub.1 -C.sub.6 alkyl optionally substituted by phenyl or by a monocycloalkyl group or by a pentatomic or hexatomic heteromonocyclic ring containing at least one heteroatom chosen from O, S and N;(2) ##STR2## wherein each of R" and R"', is independently, hydrogen; C.sub.1 -C.sub.6 alkyl; phenyl; or a pentatomic or hexatomic heteromonocyclic ring containing at least one heteroatom chosen from O, S and N; or R" and R"', together with the nitrogen atom to which they are linked, form a pentatomic or hexatomic heteromonocyclic ring optionally containing a further heteroatom chosen from O, S and N;(3) --W--(CH.sub.2).sub.
    Type: Grant
    Filed: November 1, 1984
    Date of Patent: April 29, 1986
    Assignee: Farmitalia Carlo Erba, S.p.A.
    Inventors: Franco Faustini, Achille Panzeri, Fabrizio Orzi, Enrico di Salle, Roberto Ceserani
  • 13,14-Didehydro-prostaglandins and process for their preparation
    Patent number: 4551476
    Abstract: Omega furyl prostenynoic acids have been prepared.
    Type: Grant
    Filed: May 10, 1983
    Date of Patent: November 5, 1985
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Franco Faustini, Carlo Passarotti, Roberto Ceserani, Carmelo Gandolfi
  • Ester and amide derivatives of 13,14-didehydro prostaglandins
    Patent number: 4543353
    Abstract: Esters of 13,14-didehydro prostaglandins have been prepared.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: September 24, 1985
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Franco Faustini, Vittoria Villa, Carmelo Gandolfi, Enrico Di Salle
  • Certain PGI.sub.1 compounds and their pharmaceutical composition and methods
    Patent number: 4328240
    Abstract: 2-oxa-bicyclic prostaglandins are provided, together with methods for their preparation and pharmaceutical and veterinary compositions containing same. The compounds have a wide range of pharmacological utilities, such as hypotensive agents, vasodilatory agents, and anti-aggregating agents.
    Type: Grant
    Filed: July 28, 1978
    Date of Patent: May 4, 1982
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Ceserani, Maria M. Usardi
  • 9-Deoxy-9A-methylene isosteres of PGI.sub.2 and process for their preparation
    Patent number: 4307112
    Abstract: 9-deoxy-9A-methylene-isosteres of PGI.sub.2, including processes for their preparation and pharmaceutical and veterinary compositions containing same, are disclosed. The compounds are useful as therapeutic agents, for example as anti-aggregating agents, disaggregating agents, and as vasodilators.
    Type: Grant
    Filed: February 26, 1980
    Date of Patent: December 22, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, William Fava, Angelo Fumagalli, Franco Faustini, Roberto Ceserani
  • Bicyclic prostaglandins and process for their preparation
    Patent number: 4303670
    Abstract: Bicyclic prostaglandins and pharmaceutical and veterinary compositions containing them having numerous pharmaceutical or veterinary utilities, including, for example, hypotensive, vasodilatory, anti-aggregating, luteolytic, and cytoprotective activities. Processes for preparing the compounds and compositions are also disclosed.
    Type: Grant
    Filed: April 13, 1979
    Date of Patent: December 1, 1981
    Assignee: Farmitalia Carlo Erba
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Ceserani, Maria M. Usardi
  • Pharmaceutically useful 5,6-saturated PGI compounds
    Patent number: 4297368
    Abstract: Bicyclic prostaglandins and pharamaceutical and veterinary compositions containing them having numerous pharmaceutical or veterinary utilities, including, for example, hypotensive, vasodilatory, anti-aggregating, luteolytic, and cytoprotective activities. Processes for preparing the compounds and compositions are also disclosed.
    Type: Grant
    Filed: June 29, 1978
    Date of Patent: October 27, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Ceserani, Maria M. Usardi
  • 13,14-Dehydro-11-deoxy-prostaglandins and process for their preparation
    Patent number: 4293705
    Abstract: Novel optically active 13,14-dehydro-11-deoxy-prostaglandins having a phenyl or substituted-phenyl group on the lower side chain are disclosed.
    Type: Grant
    Filed: February 19, 1980
    Date of Patent: October 6, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Renato Pellegata, Franco Faustini, Angelo Fumagalli
  • Certain 15-epi-prostacyclins
    Patent number: 4285966
    Abstract: The present invention relates to 15-epi-derivatives of prostacyclin and its analogs, to a process for their preparation and to pharmaceutical and veterinary compositions containing them.
    Type: Grant
    Filed: October 30, 1978
    Date of Patent: August 25, 1981
    Assignee: Farmitalia Carlo Erba, S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Cesarani
  • Bicyclic prostaglandins
    Patent number: 4277491
    Abstract: Bicyclic prostaglandins and pharmaceutical and veterinary compositions containing them having numerous pharmaceutical or veterinary utilities including, for example, hypotensive, vasodilatory, anti-aggregating, luteolytic, and cytoprotective activities. Processes for preparing the compounds are also disclosed.
    Type: Grant
    Filed: December 1, 1978
    Date of Patent: July 7, 1981
    Assignee: Farmitalia Carlo Erba, S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Ceserani, Maria M. Usardi
  • Bicyclic prostaglandins
    Patent number: 4271183
    Abstract: Bicyclic prostaglandins and pharmaceutical and veterinary compositions containing them having numerous pharmaceutical or veterinary utilities including, for example, hypotensive, vasodilatory, anti-aggregating, luteolytic, and cytoprotective activities. Processes for preparing the compounds and compositions are also disclosed.
    Type: Grant
    Filed: April 13, 1979
    Date of Patent: June 2, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Ceserani, Maria M. Usardi
  • Bicyclic prostaglandins
    Patent number: 4271184
    Abstract: Bicyclic prostaglandins and pharmaceutical and veterinary compositions containing them having numerous pharmaceutical or veterinary utilities including, for example, hypotensive, vasodilatory, antiaggregating, luteolytic, and cytoprotective activities. Processes for preparing the compounds and compositions are also disclosed.
    Type: Grant
    Filed: November 30, 1979
    Date of Patent: June 2, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Ceserani, Maria M. Usardi
  • Bicyclic prostaglandins and process for their preparation
    Patent number: 4262016
    Abstract: Bicyclic Prostaglandins and pharmaceutical and veterinary compositions containing them, having numerous pharmaceutical and veterinary utilities, including for example hypotensive, vasodilatory, anti-aggregating, and anti-thrombotic activities. Methods for preparing the compounds and compositions are also disclosed.
    Type: Grant
    Filed: June 18, 1979
    Date of Patent: April 14, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Ceserani, Maria M. Usardi
  • Certain 13,14-didehydro-PGI.sub.1 compounds
    Patent number: 4259244
    Abstract: Bicyclic prostaglandins having numerous pharmaceutical and veterinary utilities including, for example, use as hypotensive, vasodilatory, anti-aggregating, cytoprotective, and bronchodilatory agents. Pharmaceutical and veterinary compositions comprising the compounds in combination with pharmaceutically and/or veterinarily acceptable carriers and/or diluents are also disclosed.
    Type: Grant
    Filed: April 13, 1979
    Date of Patent: March 31, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Ceserani, Maria M. Usardi
  • Bicyclic prostaglandins and process for their preparation
    Patent number: 4254137
    Abstract: Bicyclic prostaglandins and pharmaceutical and veterinary compositions containing them, having numerous pharmaceutical and veterinary utilities, including for example hypotensive, vasodilatory, anti-aggregating, and anti-thrombotic activities. Methods for preparing the compounds and compositions are also disclosed.
    Type: Grant
    Filed: June 18, 1979
    Date of Patent: March 3, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Ceserani, Maria M. Usardi
  • Certain PGI.sub.1 compounds and pharmaceutical compositions containing them
    Patent number: 4250188
    Abstract: 2-Oxa-bicyclic prostaglandins, a method for their preparation and pharmaceutical and veterinary compositions containing them are disclosed.
    Type: Grant
    Filed: November 1, 1979
    Date of Patent: February 10, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, Alessandro Andreoni, Angelo Fumagalli, Franco Faustini, Roberto Ceserani, Maria M. Usardi