Abstract: A bone prosthesis has a portion of interface with the bone which comprises a porous layer (2) with cavities (3, 4) having prefixed and reproducible dimensions and arrangement, and at least one osteoinductive layer containing one or more chemical compounds that can stimulate and promote the growth of bone tissue.

Abstract: A device for the pulsed pumping of liquids, particularly blood, has a body in which are formed a pumping chamber in which a pulsed flow is imparted to the liquid, an inlet duct upstream of the pumping chamber and communicating therewith, and a delivery duct downstream of the pumping chamber and communicating therewith. Two valve members constituted by lip valves are provided for regulating the one-way flow of fluid in the body from the inlet duct to the pumping chamber and from the latter to the delivery duct. Low levels of hemolysis can be achieved, if the device is pumping blood. Moreover, the device has a low production cost and is quiet. The pumping device may be incorporated into a cardiopulmonary bypass device which includes a venous reservoir, a heat exchanger and an oxygenator.