Abstract: A case for the safe transport of guns with associated holster, comprising a box-like body constituted by a bottom element and by a lid connected to the bottom element by means of hinge elements for moving the box-like body from an open configuration to a closed configuration and vice versa. The bottom element and the lid are provided with closure elements which can engage each other to keep the box-like body in the closed configuration; in the bottom element there is a housing compartment intended to contain a gun inserted in a respective holster; elements are further provided for the removable engagement of the holster with the box-like body so as to retain the holster in the housing compartment, the holster allowing, in association with the case, completely safe transport of the weapon in a closed compartment.