Abstract: The present invention relates to a method for radioiodination or radioastatination of a biomolecule such as proteins and antibodies by reacting a biomolecule carrying a hetero(aryl) boronic acid group with a radioiodide or astatide salt, in the presence of a catalyst and a ligand, in a buffer solution, in order to obtain a radioiodo- or astatolabeled biomolecule. The method of the invention is thus a single step method easy to be implemented and efficient for both radioiodination and radioastatination of antibodies.

Abstract: The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene.

Abstract: The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene.

Abstract: The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene.

Abstract: The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene.

Abstract: Disclosed is a compound of formula (I) or (II) in which R1-R4, R1?-R5?, Z1+-Z4, and Z1?-Z4? are as described herein. Also disclosed are a 89Zr- or 90Nb-containing complex of a compound of formula (I) or (II) and a method for obtaining a diagnostic image, such as a positron emission tomography (PET) image.

Abstract: The present invention relates to a compound having formula (I): wherein: —X is in particular 125I Or 211At; —R1 and R?1 are independently from each other chosen preferably from the group consisting of electron-withdrawing groups and alkyl groups; —R2 is chosen from the group consisting of: H, alkyl groups, functional groups being able to bind a vector, and functional groups having targeting properties which make the compound of the invention a vector itself; —Z is a heteroatom, R5, R8 and R9 are preferably H; —Y is preferably an electron withdrawing group.

Abstract: Disclosed is a compound of formula (I) or (II) in which R1-R4, R1?-R5?, Z1+-Z4, and Z1?-Z4? are as described herein. Also disclosed are a 89Zr- or 90Nb-containing complex of a compound of formula (I) or (II) and a method for obtaining a diagnostic image, such as a positron emission tomography (PET) image.

Abstract: The present invention relates to a compound having formula (I): wherein: X is in particular 125I Or 211At; R1 and R?1 are independently from each other chosen preferably from the group consisting of electron-withdrawing groups and alkyl groups; R2 is chosen from the group consisting of: H, alkyl groups, functional groups being able to bind a vector, and functional groups having targeting properties which make the compound of the invention a vector itself; Z is a heteroatom, R5, R8 and R9 are preferably H; Y is preferably an electron withdrawing group.

Abstract: The hair-curler is comprised of two parts capable of being assembled, a first part having a socket (20) and a plurality of rectilinear or curved cylindrical pins (21, 22, 23) and having a pointed end and a second part comprising a socket (30) provided with holes (31, 32, 33) for the points and pins (27, 28, 29) intended to be alternatingly arranged with the pins of the first part. The pins (27, 28, 29) are either fixed to the socket (30) or removable and individually mounted on said socket, slots (34, 35, 36) being then provided.