Patents by Inventor Francois J. Roman

Francois J. Roman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190046472
    Abstract: The present invention relates to methods for treating neurodegenerative diseases and disorders with igmesine.
    Type: Application
    Filed: February 10, 2017
    Publication date: February 14, 2019
    Inventors: Fran├žois J. Roman, Johann Meunier
  • Publication number: 20040266802
    Abstract: A tricyclic compound of Formula (I): wherein: R1 is hydrogen or hydroxy; R2 is hydrogen or hydroxy; or R1 and R2 together are oxygen; A is a bond, CH2, CH CH3, CH2 CH2 or C(CH3)2; R3 and R4 are the same or different and are hydrogen, halo, C1-C6 alkyl, C1-C4 alkoxy, trifluoromethyl NO2, COR6, COOR6 or NR6R7, wherein R6 and R7 are the same or different and are hydrogen, C1-C6 alkyl or benzyl; R5 is hydrogen, C1-6 alkyl, C2-6 alkenyl, C3-6 cycloalkyl, (O═C)—C1-6 alkyl, (O═C)—C2-6 alkenyl, (O═C)—C3-6 cycloalkyl wherein said alkyl, alkenyl and cycloalkyl groups can be substituted by 1, 2 or 3 groups selected from halo, C3-C6 cycloalkyl, phenyl or substituted phenyl, and salts thereof, are particularly useful for treating, among other indications, neuropathic pain and other CNS disorders.
    Type: Application
    Filed: July 22, 2004
    Publication date: December 30, 2004
    Inventors: Alain Calvet, Henri Jacobelli, Jocelyne Puaud, Francois J. Roman, Jacques Hamon, Agnes Grouhel
  • Patent number: 5362756
    Abstract: A process for inhibiting functional ileus in a patient, which consists of administering a therapeutically effective dose of (+)-1-1[(3,4,5-trimethoxy)benzyloxymethyl]-1-phenyl-N,N dimethylpropylamine or the addition salt thereof with (-)-tartaric acid is disclosed.
    Type: Grant
    Filed: August 31, 1992
    Date of Patent: November 8, 1994
    Inventors: Pierre J. M. Riviere, Xavier B. Pascaud, Francois J. Roman, Jean-Louis Junien
  • Patent number: 5266599
    Abstract: (+)-1-[(3,4,5-trimethoxy)-benzyloxymethyl]-1-phenyl-N,N-dimethyl-n-propylam ine of formula ##STR1## is a medicament of use in gastroenterology.
    Type: Grant
    Filed: August 19, 1992
    Date of Patent: November 30, 1993
    Assignee: Jouveinal S.A.
    Inventors: Gilbert G. Aubard, Alain P. Calvet, Agnes Grouhel, Henri Jacobelli, Jean-Louis Junien, Xavier B. Pascaud, Francois J. Roman
  • Patent number: 5082937
    Abstract: Benzodiazepines of formula ##STR1## in which R.sup.9 is hydrogen or chlorine, R10 is phenyl, possibly substituted, R11 is hydrogen, R12 is oxygen or sulphur, R13 is an NH group, Ar is aromatic or heteroaromatic comprising one or more rings and in which, in particular, A is an ethylene or trimethylene bridge; e is 1 or 2; which are gastrin antagonists and/or central antagonists of cholecystokinin.
    Type: Grant
    Filed: September 18, 1990
    Date of Patent: January 21, 1992
    Assignee: Jouveinal S.A.
    Inventors: Alain P. Calvet, Jean-Louis Junien, Yves R. Pascal, Xavier B. Pascaud, Francois J. Roman
  • Patent number: 5017723
    Abstract: Substituted ethylamines of the formula ##STR1## wherein R.sub.1 is phenyl optionally mono-, di- or trisubstituted by halogen, lower alkyl, lower haloalkyl or lower alkoxy, or is an aromatic heterocycle having 5 to 7 chains wherein the heteroatom is nitrogen, oxygen or sulfur,R.sub.2 is lower alkyl,R.sub.3 and R.sub.4, each independently, represent hydrogen, lower alkyl or lower alkenyl,R.sub.5 is phenyl optionally mono-, di- or trisubstituted by halogen or lower alkoxy or is an aromatic heterocycle having 5 to 7 chains wherein the heteroatom is nitrogen, oxygen or sulfur andQ represents a --CH.dbd.CH-- ethylene group or a 1,2-diyl ##STR2## propane group, their acid addition salts and their optically active forms. These substituted ethylamines have psycotropic properties and are useful as medicines.
    Type: Grant
    Filed: February 26, 1990
    Date of Patent: May 21, 1991
    Assignee: Jouveinal S.A.
    Inventors: Gilbert G. Aubard, Alain P. Calvet, Claude J. Gouret, Agnes M. Grouhel, Henry L. Jacobelli, Jean-Louis Junien, Xavier B. Pascaud, Francois J. Roman, Claude D. Soulard, James P. Hudspeth, Yuan Lin
  • Patent number: 4929614
    Abstract: Benzodiazepines of formula ##STR1## in which R.sub.1 is H of halogen, R.sub.2 is H or halogen, Ar is indolyl, phenyl, naphthyl, indolyl monosubstituted with a halogen or with a methoxy or phenyl mono-, di- or trisubstituted with a halogen or with a methoxy or with a trifluoromethyl group, and n is 2 or 3; and their optical isomers.
    Type: Grant
    Filed: April 14, 1989
    Date of Patent: May 29, 1990
    Assignee: Jouveinal S.A.
    Inventors: Alain P. Calvet, Jean-Louis Junien, Ives R. Pascal, Xavier B. Pascaud, Francois J. Roman