Patents by Inventor Francois Maingret

Francois Maingret has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the identification of anesthetics
    Patent number: 7112403
    Abstract: Human and mouse TREK-1 potassium transport proteins are disclosed as well a method for using potassium transport proteins for identifying substances having anesthetic properties, such as producing a safe, reversible state of unconsciousness with concurrent amnesia and analgesia in a mammal upon inhalation, in a method comprising (a) contacting the test substance with a mammalian potassium transport protein, wherein said potassium transport protein exhibits outward-going potassium rectification; and (b) determining the potassium transport activity of the potassium transport protein, wherein an activation of potassium transport is indicative of the test substance having anesthetic properties.
    Type: Grant
    Filed: February 11, 2000
    Date of Patent: September 26, 2006
    Assignees: Centre National de la Recherche Scientifique, CNRS and Fabrice Duprat
    Inventors: Amanda J. Patel, Eric Honore, Florian Lesage, Georges Romey, Michel Lazdunski, Michel Fink, Fabrice Duprat, Francois Maingret
  • Family of mechanosensitive human potassium channels activated by polyunsaturated fatty acids and their use
    Publication number: 20030049697
    Abstract: A mechanosensitive human potassium channel, referred to as “hTRAAK” for human TWICK-Related AA-Activated K+ channel, which is activated by polyunsaturated fatty acids as well as by the neuroprotective agent riluzole. The properties of the channels of the TRAAK family as well as their tissue distribution give these channels a primordial role in the transport of potassium in a large number of cell types.
    Type: Application
    Filed: September 13, 2002
    Publication date: March 13, 2003
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, C.N.R.S.
    Inventors: Michel Lazdunski, Florian Lesage, Francois Maingret