Patents by Inventor Francois Morvan

Francois Morvan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11934586
    Abstract: Techniques of operating an AR system include determining hand gestures formed by a user based on a sequence of two-dimensional images through skin of the user's wrist acquired from a near-infrared camera. Specifically, an image capture device disposed on a band worn around a user's wrist includes a source of electromagnetic radiation, e.g., light-emitting diodes in the infrared (IR) wavelength band that emit the radiation into the user's wrist and an IR detector which produces the sequence of two-dimensional images of a region within a dermal layer in the user's wrist. From this sequence, gesture detection circuitry determines values of a biological flow metric, e.g., a change in perfusion index (PI) between frames of the sequence, based on a trained model that generates the metric from the sequence. Finally, the gesture detection circuitry maps the values of the biological flow metric to specific hand/finger movements that determine a gesture.
    Type: Grant
    Filed: June 29, 2022
    Date of Patent: March 19, 2024
    Assignee: GOOGLE LLC
    Inventors: Dongeek Shin, Andrea Colaco, Stiven Guillaume Francois Morvan, Adam James Banfield, Shahram Izadi
  • Publication number: 20240004476
    Abstract: Techniques of operating an AR system include determining hand gestures formed by a user based on a sequence of two-dimensional images through skin of the user's wrist acquired from a near-infrared camera. Specifically, an image capture device disposed on a band worn around a user's wrist includes a source of electromagnetic radiation, e.g., light-emitting diodes in the infrared (IR) wavelength band that emit the radiation into the user's wrist and an IR detector which produces the sequence of two-dimensional images of a region within a dermal layer in the user's wrist. From this sequence, gesture detection circuitry determines values of a biological flow metric, e.g., a change in perfusion index (PI) between frames of the sequence, based on a trained model that generates the metric from the sequence. Finally, the gesture detection circuitry maps the values of the biological flow metric to specific hand/finger movements that determine a gesture.
    Type: Application
    Filed: June 29, 2022
    Publication date: January 4, 2024
    Inventors: Dongeek Shin, Andrea Colaco, Stiven Guillaume Francois Morvan, Adam James Banfield, Shahram Izadi
  • Patent number: 11390643
    Abstract: The present invention relates to a modified oligonucleotide having two or more thiol functions, which can be immobilized on a gold surface or on a grafted surface, in particular a surface comprising at least one carbon-carbon double bond or carbon-carbon triple bond or haloacetamide functions, preferably maleimide or acrylamide functions. The invention also relates to a method for detecting a nucleic acid in a biological sample comprising a step of detecting hybridization between a modified oligonucleotide and a target nucleic acid amplified from the biological sample. The invention relates more particularly to a method for detecting, genotyping or sequencing a pathogenic organism, preferably a virus.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: July 19, 2022
    Assignees: ETABLISSEMENT FRANÇAIS DU SANG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE MONTPELLIER, UNIVERSITE CLAUDE BERNARD LYON 1
    Inventors: Chantal Fournier-Wirth, Myriam Lereau, Jean-François Cantaloube, Jean-Jacques Vasseur, François Morvan, Albert Meyer, Julie Mayen, Carole Chaix, Carole Farre
  • Patent number: 11078229
    Abstract: The present invention relates to a thiol compound suitable for forming a chain of oligomers that can be grafted to an oligonucleotide. The invention also relates to an oligonucleotide grafted by such a compound, thus having one or more thiol functions, suitable for being immobilized on a gold surface or on a grafted surface.
    Type: Grant
    Filed: January 4, 2018
    Date of Patent: August 3, 2021
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ETABLISSEMENT FRANCAIS DU SANG
    Inventors: François Morvan, Albert Meyer, Jean-Jacques Vasseur, Julie Mayen, Carole Chaix, Carole Farre, Chantal Fournier-Wirth, Jean-François Cantaloube, Myriam Lereau
  • Publication number: 20190376151
    Abstract: The present invention relates to a modified oligonucleotide having two or more thiol functions, which can be immobilized on a gold surface or on a grafted surface, in particular a surface comprising at least one carbon-carbon double bond or carbon-carbon triple bond or haloacetamide functions, preferably maleimide or acrylamide functions. The invention also relates to a method for detecting a nucleic acid in a biological sample comprising a step of detecting hybridization between a modified oligonucleotide and a target nucleic acid amplified from the biological sample. The invention relates more particularly to a method for detecting, genotyping or sequencing a pathogenic organism, preferably a virus.
    Type: Application
    Filed: February 8, 2019
    Publication date: December 12, 2019
    Inventors: Chantal Fournier-Wirth, Myriam Lereau, Jean-François Cantaloube, Jean-Jacques Vasseur, François Morvan, Albert Meyer, Julie Mayen, Carole Chaix, Carole Farre
  • Patent number: 10105380
    Abstract: A molecule responding to formula (I) of the glycocluster type with galactose residues at their extremities. Simple and efficient methods for the preparation of these compounds. Medical use of compounds (I) as inhibitors of infections by Pseudomonas aeruginosa, more specifically as inhibitors of Pseudomonas aeruginosa's virulence.
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: October 23, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER 1
    Inventors: Francois Morvan, Jean-Jacques Vasseur, Caroline Ligeour, Yann Chevolot, Eliane Souteyrand, Olivier Vidal, Alice Goudot, Sebastien Vidal
  • Publication number: 20180265538
    Abstract: The present invention relates to a thiol compound suitable for forming a chain of oligomers that can be grafted to an oligonucleotide. The invention also relates to an oligonucleotide grafted by such a compound, thus having one or more thiol functions, suitable for being immobilized on a gold surface or on a grafted surface.
    Type: Application
    Filed: January 4, 2018
    Publication date: September 20, 2018
    Inventors: François Morvan, Albert Meyer, Jean-Jacques Vasseur, Julie Mayen, Carole Chaix, Carole Farre, Chantal Fournier-Wirth, Jean-François Cantaloube, Myriam Lereau
  • Patent number: 9896473
    Abstract: The present invention relates to a thiol compound suitable for forming a chain of oligomers that can be grafted to an oligonucleotide. The invention also relates to an oligonucleotide grafted by such a compound, thus having one or more thiol functions, suitable for being immobilized on a gold surface or on a grafted surface.
    Type: Grant
    Filed: April 4, 2013
    Date of Patent: February 20, 2018
    Assignees: Etablissement Francais du Sang, Centre National de la Recherche Scientifique (CNRS)
    Inventors: François Morvan, Albert Meyer, Jean-Jacques Vasseur, Julie Mayen, Carole Chaix, Carole Farre, Chantal Fournier-Wirth, Jean-François Cantaloube, Myriam Lereau
  • Publication number: 20160287620
    Abstract: A molecule responding to formula (I)of the glycocluster type with galactose residues at their extremities. Simple and efficient methods for the preparation of these compounds. Medical use of compounds (I) as inhibitors of infections by Pseudomonas aeruginosa, more specifically as inhibitors of Pseudomonas aeruginosa's virulence.
    Type: Application
    Filed: September 22, 2014
    Publication date: October 6, 2016
    Inventors: Francois MORVAN, Jean-Jacques VASSEUR, Caroline LIGEOUR, Yann CHEVOLOT, Eliane SOUTEYRAND, Olivier VIDAL, Alice GOUDOT, Sebastien VIDAL
  • Publication number: 20150232957
    Abstract: The present invention relates to a modified oligonucleotide having two or more thiol functions, which can be immobilized on a gold surface or on a grafted surface, in particular a surface comprising at least one carbon-carbon double bond or carbon-carbon triple bond or haloacetamide functions, preferably maleimide or acrylamide functions. The invention also relates to a method for detecting a nucleic acid in a biological sample comprising a step of detecting hybridization between a modified oligonucleotide and a target nucleic acid amplified from the biological sample. The invention relates more particularly to a method for detecting, genotyping or sequencing a pathogenic organism, preferably a virus.
    Type: Application
    Filed: April 4, 2013
    Publication date: August 20, 2015
    Inventors: Chantal Fournier-Wirth, Myriam Lereau, Jean-François Cantaloube, Jean-Jacques Vasseur, François Morvan, Albert Meyer, Julie Mayen, Carole Chaix, Carole Farre
  • Publication number: 20150158964
    Abstract: The present invention relates to a thiol compound suitable for forming a chain of oligomers that can be grafted to an oligonucleotide. The invention also relates to an oligonucleotide grafted by such a compound, thus having one or more thiol functions, suitable for being immobilized on a gold surface or on a grafted surface.
    Type: Application
    Filed: April 4, 2013
    Publication date: June 11, 2015
    Applicant: UNIVERSITE CLAUDE BERNARD LYON 1
    Inventors: François Morvan, Albert Meyer, Jean-Jacques Vasseur, Julie Mayen, Carole Chaix, Carole Farre, Chantal Fournier-Wirth, Jean-François Cantaloube, Myriam Lereau
  • Patent number: 9035041
    Abstract: This invention relates to a process for preparing an oligonucleotide 5?-triphosphate.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: May 19, 2015
    Assignee: Alnylam Pharmaceuticals, Inc.
    Inventors: Ivan Zlatev, Francois Morvan, Jean-Jacques Vasseur, Francoise Debart, Muthiah Manoharan
  • Patent number: 8304532
    Abstract: A solution phase synthesis method for preparing an oligonucleotide, wherein at least some of the reagents are solid supported. The method suitable for large-scale synthesis comprises coupling a protected compound with a nucleotide derivative having a protection group in the presence of a solid supported activator to give an elongated oligonucleotide with a P(III)-internucleotide bond; optionally processing the elongated oligonucleotide by capping by reaction with a solid supported capping agent and/or by oxidizing or sulfurizing by reaction of the oligonucleotide with a solid supported oxidizing or sulfurization reagent; and removing the protection group. The coupling may include reacting a 3?-protected compound of formula: with a nucleotide derivative having a 5?-protection group, or reacting a 5?-protected compound of formula with a nucleotide derivative having a 3?-protection group.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: November 6, 2012
    Assignees: Girindus AG, Centre National de la Recherche Scientifique, University of Montpellier II
    Inventors: Ilaria Adamo, Cecile Dueymes, Andreas Schonberger, Jean-Louis Imbach, Albert Meyer, Francois Morvan, Francoise Debart, Jean-Jacques Vasseur, Meinolf Lange, Fritz Link
  • Publication number: 20120220761
    Abstract: The present invention describes simple, efficient, and enzyme-free method of making oligonucleotides with 5?-triphosphate. This invention presents novel process for synthesizing triphosphate oligonucleotides using a diaryl phosphonate as reagent. The process of the present invention is amenable to large-scale, economic 5?-triphosphate oligonucleotide synthesis.
    Type: Application
    Filed: December 22, 2009
    Publication date: August 30, 2012
    Applicant: ALNYLAM PHARMACEUTICALS, INC.
    Inventors: Ivan Zlatev, Francois Morvan, Jean-Jacques Vasseur, Francoise Debart, Muthiah Manoharan
  • Patent number: 8183355
    Abstract: Method for the synthesis of nucleotide derivatives wherein molecules of interest are grafted on the oligonucleotide with the help of a “click chemistry” reaction between an azide function on the molecule of interest and an alkyne function on the oligonucleotide, or between an alkyne function on the molecule of interest and an azide function on the oligonucleotide. Intermediate molecules, notably alkyne functionalized oligonucleotides, grafted oligonucleotides, azide functionalized oligonucleotides, oligonucleotide micro arrays containing them and the use of those grafted oligonucleotides for biological investigation and for cell targeting.
    Type: Grant
    Filed: April 7, 2011
    Date of Patent: May 22, 2012
    Assignee: Centre National de la Recherche Scientifique (CNRS)
    Inventors: François Morvan, Albert Meyer, Jean-Jacques Vasseur, Sébastien Vidal, Jean-Pierre Cloarec, Yann Chevolot, Eliane Souteyrand
  • Publication number: 20110245478
    Abstract: Method for the synthesis of nucleotide derivatives wherein molecules of interest are grafted on the oligonucleotide with the help of a “click chemistry” reaction between an azide function on the molecule of interest and an alkyne function on the oligonucleotide, or between an alkyne function on the molecule of interest and an azide function on the oligonucleotide. Intermediate molecules, notably alkyne functionalized oligonucleotides, grafted oligonucleotides, azide functionalized oligonucleotides, oligonucleotide micro arrays containing them and the use of those grafted oligonucleotides for biological investigation and for cell targeting.
    Type: Application
    Filed: April 7, 2011
    Publication date: October 6, 2011
    Inventors: François Morvan, Albert Meyer, Jean-Jacques Vasseur, Sébastien Vidal, Jean-Pierre Cloarec, Yann Chevolot, Eliane Souteyrand
  • Publication number: 20110224424
    Abstract: A solution phase synthesis method for preparing an oligonucleotide, wherein at least some of the reagents are solid supported. The method suitable for large- scale synthesis comprises coupling a protected compound with a nucleotide derivative having a protection group in the presence of a solid supported activator to give an elongated oligonucleotide with a P(III)-internucleotide bond; optionally processing the elongated oligonucleotide by capping by reaction with a solid supported capping agent and/or by oxidizing or sulfurizing by reaction of the oligonucleotide with a solid supported oxidizing or sulfurization reagent; and removing the protection group. The coupling may include reacting a 3?-protected compound of formula: with a nucleotide derivative having a 5?-protection group, or reacting a 5?-protected compound of formula with a nucleotide derivative having a 3?-protection group.
    Type: Application
    Filed: May 25, 2011
    Publication date: September 15, 2011
    Applicants: GIRINDUS AG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITY OF MONTPELLIER II
    Inventors: Ilaria ADAMO, Cécile DUEYMES, Andreas SCHÖNBERGER, Jean-Louis IMBACH, Albert MEYER, Francois MORVAN, Francoise DEBART, Jean-Jacques VASSEUR, Meinolf LANGE, Fritz LINK
  • Patent number: 7951926
    Abstract: Method for the synthesis of nucleotide derivatives wherein molecules of interest are grafted on the oligonucleotide with the help of a “click chemistry” reaction between an azide function on the molecule of interest and an alkyne function on the oligonucleotide, or between an alkyne function on the molecule of interest and an azide function on the oligonucleotide. Intermediate molecules, notably alkyne functionalized oligonucleotides, grafted oligonucleotides, azide functionalized oligonucleotides, oligonucleotide micro arrays containing them and the use of those grafted oligonucleotides for biological investigation and for cell targeting.
    Type: Grant
    Filed: April 26, 2007
    Date of Patent: May 31, 2011
    Assignee: Centre National de la Recherche Scientifique (CNRS)
    Inventors: François Morvan, Albert Meyer, Jean-Jacques Vasseur, Sébastien Vidal, Jean-Pierre Cloarec, Yann Chevolot, Eliane Souteyrand
  • Publication number: 20100069623
    Abstract: A solution phase synthesis method for preparing an oligonucleotide, wherein at least some of the reagents are solid supported. The method suitable for large-scale synthesis comprises coupling a protected compound with a nucleotide derivative having a protection group in the presence of a solid supported activator to give an elongated oligonucleotide with a P(III)-internucleotide bond; optionally processing the elongated oligonucleotide by capping by reaction with a solid supported capping agent and/or by oxidizing or sulfurizing by reaction of the oligonucleotide with a solid supported oxidizing or sulfurization reagent; and removing the protection group. The coupling may include reacting a 3?-protected compound of formula: with a nucleotide derivative having a 5?-protection group, or reacting a 5?-protected compound of formula with a nucleotide derivative having a 3?-protection group.
    Type: Application
    Filed: April 3, 2009
    Publication date: March 18, 2010
    Applicants: GIRINDUS AG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITY OF MONTPELLIER II
    Inventors: Ilaria Adamo, Cècile Dueymes, Andreas Schönberger, Jean-Louis Imbach, Albert Meyer, Francois Morvan, Francoise Debart, Jean-Jacques Vasseur, Meinolf Lange, Fritz Link
  • Publication number: 20090124571
    Abstract: Method for the synthesis of nucleotide derivatives wherein molecules of interest are grafted on the oligonucleotide with the help of a “click chemistry” reaction between an azide function on the molecule of interest and an alkyne function on the oligonucleotide, or between an alkyne function on the molecule of interest and an azide function on the oligonucleotide. Intermediate molecules, notably alkyne functionalized oligonucleotides, grafted oligonucleotides, azide functionalized oligonucleotides, oligonucleotide micro arrays containing them and the use of those grafted oligonucleotides for biological investigation and for cell targeting.
    Type: Application
    Filed: April 26, 2007
    Publication date: May 14, 2009
    Inventors: Francois Morvan, Albert Meyer, Jean-Jacques Vasseur, Sebastien Vidal, Jean-Pierre Cloarec, Yann Chevolot, Eliane Souteyrand