Patents by Inventor Francois Nicol

Francois Nicol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable formulations of a hyaluronan-degrading enzyme
    Patent number: 9993529
    Abstract: Provided are compositions that are stable formulations of a hyaluronan-degrading enzyme or are stable co-formulations of a fast-acting insulin and a hyaluronan degrading enzyme, including a recombinant human PH20 (rHuPH20).
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: June 12, 2018
    Assignee: Halozyme, Inc.
    Inventors: Tzung-Horng Yang, Daniel Edward Vaughn, Michael James Labarre, Christopher L. Caster, Francois Nicol, Donghyun Kim
  • Production of precipitated silica employing a fast blender
    Patent number: 9902620
    Abstract: A unique method for preparing precipitated silica entails reacting a silicate with an acidifying agent to obtain a suspension of precipitated silica, and separating and drying the suspension, and further wherein the precipitation includes contacting a silicate with an acidifying agent in an acidic medium in a fast blender.
    Type: Grant
    Filed: October 8, 2014
    Date of Patent: February 27, 2018
    Assignee: Rhodia Operations
    Inventors: Elise Fournier, Jean-Claude Magne, Francois Nicol
  • PRODUCTION OF PRECIPITATED SILICA EMPLOYING A FAST BLENDER
    Publication number: 20150125376
    Abstract: A unique method for preparing precipitated silica entails reacting a silicate with an acidifying agent to obtain a suspension of precipitated silica, and separating and drying the suspension, and further wherein the precipitation includes contacting a silicate with an acidifying agent in an acidic medium in a fast blender.
    Type: Application
    Filed: October 8, 2014
    Publication date: May 7, 2015
    Inventors: Elise FOURNIER, JEAN-CLAUDE MAGNE, FRANCOIS NICOL
  • Liposome composition for targeting egfr receptor
    Patent number: 8834920
    Abstract: Short oligopeptides are provide which are capable of binding to the epidermal growth factor receptor on the surface of human tumor cells. Methods for using the peptides as targeting moieties in more complex compositions, such as conjugates of cytoxins, and/or structures, such as liposomal structures, for the purposes of drug delivery are also provided.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: September 16, 2014
    Assignee: Alza Corporation
    Inventors: Ken Shi Kun Huang, Weiming Zhang, Guoyang Zhang, Francois Nicol, Anthony Huang
  • Stable formulations of a hyaluronan-degrading enzyme related applications
    Publication number: 20130022588
    Abstract: Provided are compositions that are stable formulations of a hyaluronan-degrading enzyme or are stable co-formulations of a fast-acting insulin and a hyaluronan degrading enzyme, including a recombinant human PH20 (rHuPH20).
    Type: Application
    Filed: June 15, 2012
    Publication date: January 24, 2013
    Inventors: Tzung-Horng Yang, Daniel Edward Vaughn, Michael James Labarre, Christopher L. Caster, Francois Nicol, Donghyun Kim
  • Stable formulations of a hyaluronan-degrading enzyme
    Publication number: 20130011378
    Abstract: Provided are compositions that are stable formulations of a hyaluronan-degrading enzyme or are stable co-formulations of a fast-acting insulin and a hyaluronan degrading enzyme, including a recombinant human PH20 (rHuPH20).
    Type: Application
    Filed: June 15, 2012
    Publication date: January 10, 2013
    Inventors: Tzung-Horng Yang, Daniel Edward Vaughn, Michael James Labarre, Christopher L. Caster, Francois Nicol, Donghyun Kim
  • LIPOSOME COMPOSITION FOR TARGETING EGFR RECEPTOR
    Publication number: 20120213844
    Abstract: Short oligopeptides are provide which are capable of binding to the epidermal growth factor receptor on the surface of human tumor cells. Methods for using the peptides as targeting moieties in more complex compositions, such as conjugates of cytoxins, and/or structures, such as liposomal structures, for the purposes of drug delivery are also provided.
    Type: Application
    Filed: December 20, 2007
    Publication date: August 23, 2012
    Inventors: Ken Shi Kun Huang, Weiming Zhang, Guoyang Zhang, Francois Nicol, Anthony Huang
  • PRODUCTION OF PRECIPITATED SILICA EMPLOYING A FAST BLENDER
    Publication number: 20110129401
    Abstract: A unique method for preparing precipitated silica entails reacting a silicate with an acidifying agent to obtain a suspension of precipitated silica, and separating and drying the suspension, and further wherein the precipitation includes contacting a silicate with an acidifying agent in an acidic medium in a fast blender.
    Type: Application
    Filed: December 21, 2007
    Publication date: June 2, 2011
    Inventors: Elise Fournier, Jean-Claude Magne, Francois Nicol
  • Nucleic acid formulations for gene delivery and methods of use
    Patent number: 7491537
    Abstract: A nucleic acid formulation for use in gene delivery comprising a nucleic acid and an anionic polymer is disclosed. Examples of the anionic polymer includes anionic amino acid polymer or poly-amino acid (such as poly-L-glutamic acid, poly-D-glutamic acid, poly-L-aspartic acid, poly-D-aspartic acid), poly-acrylic acid, polynucleotides, poly galacturonic acid, and poly vinyl sulfate.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: February 17, 2009
    Assignee: Genetronics Biomedical Corporation
    Inventors: Jason G Fewell, Fiona MacLaughlin, Louis C Smith, Francois Nicol, Alain Rolland
  • Nucleic Acid Formulations for Gene Delivery and Methods of Use
    Publication number: 20070213287
    Abstract: A nucleic acid formulation for use in gene delivery comprising a nucleic acid and an anionic polymer is disclosed. Examples of the anionic polymer includes anionic amino acid polymer or poly-amino acid (such as poly-L-glutamic acid, poly-D-glutamic acid, poly-L-aspartic acid, poly-D-aspartic acid), poly-acrylic acid, polynucleotides, poly galacturonic acid, and poly vinyl sulfate.
    Type: Application
    Filed: November 20, 2006
    Publication date: September 13, 2007
    Applicant: GENETRONICS, INC.
    Inventors: Jason Fewell, Fiona MacLaughlin, Louis Smith, Francois Nicol, Alain Rolland
  • Nucleic acid formulations for gene delivery and methods of use
    Patent number: 7173116
    Abstract: A nucleic acid formulation for use in gene delivery comprising a nucleic acid and an anionic polymer is disclosed. Examples of the anionic polymer includes aniionic amino acid polymer or poly-amino acid (such as poly-L-glutamic acid, poly-D-glutamic acid, poly-L-aspartic acid, poly-D-aspartic acid), poly-acrylic acid, polynucleotides, poly galacturonic acid, and poly vinyl sulfate.
    Type: Grant
    Filed: September 3, 2002
    Date of Patent: February 6, 2007
    Assignee: Genetronics Biomedical Corporation
    Inventors: Jason Fewell, Fiona MacLaughlin, Louis C. Smith, Francois Nicol, Alain Rolland
  • Poloxamer and poloxamine compositions for nucleic acid delivery
    Publication number: 20060013883
    Abstract: The invention features selected polymers such as poloxamer 188 (Pluronic® F68), poloxamer 237 (Pluronic® F87), poloxamer 401 (Pluronic® L121), poloxamer 338 (Pluronic® F108), Poloxamer 124 (Pluronic® L44), Poloxamer 184 (L-64), and poloxamines (Tetronics® 904, 908, 1107, and 90R4) that enhance expression from nucleic acids when administered into an organism, in particular to muscle, and further provides selected poloxamer formulations for delivery of nucleic acids to the liver.
    Type: Application
    Filed: September 1, 2005
    Publication date: January 19, 2006
    Inventors: Francois Nicol, Jijun Wang, Michael Coleman, Fiona MacLaughlin, Alain Rolland
  • Poloxamer and poloxamine compositions for nucleic acid delivery
    Publication number: 20030206910
    Abstract: The invention features selected polymers such as poloxamer 188 (Pluronic® F68), poloxamer 237 (Pluronic® F87), poloxamer 401 (Pluronic® L121), poloxamer 338 (Pluronic® F108), Poloxamer 124 (Pluronic® L44), Poloxamer 184 (L-64), and poloxamines (Tetronics® 904, 908, 1107, and 90R4) that enhance expression from nucleic acids when administered into an organism, in particular to muscle, and further provides selected poloxamer formulations for delivery of nucleic acids to the liver.
    Type: Application
    Filed: September 3, 2002
    Publication date: November 6, 2003
    Inventors: Francois Nicol, Jijun Wang, Michael E. Coleman, Fiona MacLaughlin, Alain Rolland
  • Nucleic acid formulations for gene delivery and methods of use
    Publication number: 20030109478
    Abstract: A nucleic acid formulation for use in gene delivery comprising a nucleic acid and an anionic polymer is disclosed. Examples of the anionic polymer includes aniionic amino acid polymer or poly-amino acid (such as poly-L-glutamic acid, poly-D-glutamic acid, poly-L-aspartic acid, poly-D-aspartic acid), poly-acrylic acid, polynucleotides, poly galacturonic acid, and poly vinyl sulfate.
    Type: Application
    Filed: September 3, 2002
    Publication date: June 12, 2003
    Applicant: Valentis, Inc.
    Inventors: Jason Fewel, Fiona MacLaughlin, Louis C. Smith, Francois Nicol, Alain Rolland