Patents by Inventor Francois Simon
Francois Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8227185Abstract: Retroviral strains of the non-M, non-O HIV-1 group, in particular a strain designated YBF30, its fragments and also its uses as a diagnostic reagent and as an immunogenic agent. The HIV-1 viruses which differ both from the M group and the O group exhibit the following characteristics: little or no serological reactivity with regard to the proteins of the M and O groups and strong serological reactivity with regard to the proteins which are derived from the strain YBF30 according to the invention or the strain CPZGAB SIV; absence of genomic amplification when using primers from the env and gag regions of the M and O HIV-1 groups; genomic amplification in the presence of primers which are derived from the YBF30 strain according to the invention; and homology of the products of the envelope gene which is greater than 70% with regard to the YBF30 strain.Type: GrantFiled: April 24, 2009Date of Patent: July 24, 2012Assignee: Institute National de la Sante et de la Recherche Medical-InsermInventors: Phillippe Mauclere, Ibtissam Loussert-Ajaka, Francois Simon, Sentob Saragosti, Francoise Barre-Sinoussi
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Publication number: 20100184014Abstract: Retroviral strains of the non-M, non-O HIV-1 group, in particular a strain designated YBF30, its fragments and also its uses as a diagnostic reagent and as an immunogenic agent. The HIV-1 viruses which differ both from the M group and the O group exhibit the following characteristics: little or no serological reactivity with regard to the proteins of the M and O groups and strong serological reactivity with regard to the proteins which are derived from the strain YBF30 according to the invention or the strain CPZGAB SIV; absence of genomic amplification when using primers from the env and gag regions of the M and O HIV-1 groups; genomic amplification in the presence of primers which are derived from the YBF30 strain according to the invention; and homology of the products of the envelope gene which is greater than 70% with regard to the YBF30 strain.Type: ApplicationFiled: April 24, 2009Publication date: July 22, 2010Inventors: Phillippe Mauclere, Ibtissam Loussert-Ajaka, Francois Simon, Sentob Saragosti, Francoise Barre-Sinoussi
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Patent number: 7534877Abstract: Retroviral strains of the non-M, non-O HIV-1 group, in particular a strain designated YBE30, its fragments and also its uses as a diagnostic reagent and as an immunogenic agent. The HIV-1 viruses which differ both from the M group and the O group exhibit the following characteristics: little or no serological reactivity with regard to the proteins of the M and O groups and strong serological reactivity with regard to the proteins which are derived from the strain YBF30 according to the invention or the strain CPZGAB SIV; absence of genomic amplification when using primers from the env and gag regions of the M and O HIV-1 groups; genomic amplification in the presence of primers which are derived from the YBF30 strain according to the invention; and homology of the products of the envelope gene which is greater than 70% with regard to the YBF30 strain.Type: GrantFiled: September 15, 2005Date of Patent: May 19, 2009Assignees: Institute National de la Sante et de la Recherche Medicale-Inserm, Assitance Publique-Hopitaux de Paris, Institut PasteurInventors: Phillippe Mauclere, Ibtissam Loussert-Ajaka, Francois Simon, Sentob Saragosti, Francoise Barre-Sinoussi
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Publication number: 20080245884Abstract: The invention concerns a device comprising a rotary body (1) made of a fibrous or porous material, means for rotating (3, 4) said body (1) and means for inputting liquid (10, 11) contacting said body (1), so as to subject said liquid to the dispersing action of forces at the liquid/solid interface, and to rotate the body (1) so as to subject the comminuted liquid to a centrifugal force.Type: ApplicationFiled: June 29, 2006Publication date: October 9, 2008Inventors: Francois Simon, Sandre Simon
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Publication number: 20070190524Abstract: Retroviral strains of the non-M, non-O HIV-1 group, in particular a strain designated YBF30, its fragments and also its uses as a diagnostic reagent and as an immunogenic agent. The HIV-1 viruses which differ both from the M group and the O group exhibit the following characteristics: little or no serological reactivity with regard to the proteins of the M and O groups and strong serological reactivity with regard to the proteins which are derived from the strain YBF30 according to the invention or the strain CPZGAB SIV; absence of genomic amplification when using primers from the env and gag regions of the M and O HIV-1 groups; genomic amplification in the presence of primers which are derived from the YBF30 strain according to the invention; and homology of the products of the envelope gene which is greater than 70% with regard to the YBF30 strain.Type: ApplicationFiled: September 15, 2005Publication date: August 16, 2007Inventors: Phillippe Mauclere, Ibtissam Loussert-Ajaka, Francois Simon, Sentob Saragosti, Francoise Barre-Sinoussi
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Publication number: 20060137313Abstract: The invention relates to a rotary machine comprising a rotor (6) bearing a packing (9) in the form of a ring which is at least partially made from a flexible, fluid-permeable material. The inventive machine also comprises variable-speed drive means for rotating the rotor (6) and means which enable the aforementioned packing (9) to be deformed in response to a variation in the rotational speed of the rotor (6). As a result, the machine can produce an air flow, extract material contained in said flow and perform a self-cleaning cycle.Type: ApplicationFiled: December 30, 2003Publication date: June 29, 2006Inventors: Francois Simon, Sandre Simon
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Patent number: 7030234Abstract: Retroviral strains of the non-M, non-O HIV-1 group, in particular a strain designated YBF30, its fragments and also its uses as a diagnostic reagent and as an immunogenic agent. The HIV-1 viruses which differ both from the M group and the O group exhibit the following characteristics: little or no serological reactivity with regard to the proteins of the M and O groups and strong serological reactivity with regard to the proteins which are derived from the strain YBF30 according to the invention or the strain CPZGAB SIV; absence of genomic amplification when using primers from the env and gag regions of the M and O HIV-1 groups; genomic amplification in the presence of primers which are derived from the YBF30 strain according to the invention; and homology of the products of the envelope gene which is greater than 70% with regard to the YBF30 strain.Type: GrantFiled: November 22, 2002Date of Patent: April 18, 2006Assignees: Institute National de la Sante et de la Recherche Medicale-Inserm, Assistance Publique-Hopitaux de Paris, Institute PasteurInventors: Phillippe Mauclere, Ibtissam Loussert-Ajaka, Francois Simon, Sentob Saragosti, Francoise Barre-Sinoussi
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Publication number: 20030157660Abstract: Retroviral strains of the non-M, non-O HIV-1 group, in particular a strain designated YBF30, its fragments and also its uses as a diagnostic reagent and as an immunogenic agent.Type: ApplicationFiled: November 22, 2002Publication date: August 21, 2003Applicant: Institute National de la Sante et de La Recherche Medicale-InsermInventors: Phillippe Mauclere, Ibtissam Loussert-Ajaka, Francois Simon, Sentob Saragosti, Francoise Barre-Sinoussi
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Patent number: 6509018Abstract: The invention provides peptides which are expressed by the env gene of a non-M, non-O HIV-1 virus, in particular a strain designated YBF30. The invention also provides fragments of the peptides that including the V3 loop region and their corresponding nucleotide sequences. The invention further provides kits including diagnostic reagents containing these molecules or immunogenic compositions containing these peptides, as well as methods for screening and typing non-M, non-O HIV-1 viruses and HIV-1 viruses expressing these peptide and/or nucleotide sequences.Type: GrantFiled: August 27, 1999Date of Patent: January 21, 2003Assignee: Institute National de la Sante et de la Recherche Medicale-InsermInventors: Phillippe Mauclere, Ibtissam Loussert-Ajaka, Francois Simon, Sentob Saragosti, Francoise Barre-Sinoussi
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Publication number: 20020006789Abstract: A process for establishing secure communication between particular communicating units via a channel of a telecommunication network encodes data embodying information to be selectively transmitted from a transmitter unit to one or more particular receiver units prior to transmission using an error detecting code enabling reliable recovery of the information on reception. For security reasons, the error detecting code used to encode the information is encrypted using an enciphering key defined by application of a time dependent variation law. Alternatively, the error detecting code used to transmit information can be selected by application of a time dependent variation law.Type: ApplicationFiled: January 5, 1999Publication date: January 17, 2002Inventors: HELENE PAPINI, FRANCOIS SIMON
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Patent number: 4700433Abstract: The device of the clevis type for handling materials, notably lifting or hauling operations, comprises two clevis branches connected by at least two stems which have non aligned parallel axes and at least one of which is slit longitudinally, a flat flexible tie in the form of a strap having one at least of its ends secured against motion by friction on the slit stem with the strap penetrating the associated slot and being lockingly wound on the slit stem, and means being provided for locking said slit stem in rotation about its axis.Type: GrantFiled: August 6, 1986Date of Patent: October 20, 1987Inventor: Francois Simon
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Patent number: 4614331Abstract: In order to bring a pulley block close to the load to be hauled, same is provided with a carriage, removable or not, and possibly completed by a drawbar, the carriage including means for rolling on the ground and means for its fixation to the pulley block.Type: GrantFiled: December 4, 1984Date of Patent: September 30, 1986Inventor: Francois Simon
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Patent number: 4343458Abstract: A support for boom end sheaves for lifting and/or handling machines, carrying at least a first sheave which receives a flexible rope, particularly a lifting cable, extending from the boom, is characterized in that it carries a pulley-block mounted on a lever which is swingingly carried by the support.Type: GrantFiled: May 16, 1980Date of Patent: August 10, 1982Inventor: Francois Simon
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Patent number: 4277053Abstract: Under the action of relative motion between a hoisting machine support and a load, a movable component such as a pulley-block carried by the hoisting machine is capable of free displacement under gravity between two end positions of abutment when that end of the movable component which is intended to cooperate with the load is stationary with respect to the load, thereby compensating for any variation in distance between the load and that portion of the hoisting machine which carries the movable component. The equipment unit is designed primarily for hoisting operations performed at sea or on wharves.Type: GrantFiled: September 29, 1978Date of Patent: July 7, 1981Inventor: Francois Simon
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Patent number: 4222551Abstract: The pulley-block balance comprises at least one loose pulley, a hollow coaxial support fitted with ball-bearings for supporting the pulley or pulleys, and a load-lifting hook. Coupling means between the hook and the support comprise a movable member which is capable of undergoing displacement at least at the point of application of the force arising from the load and is subjected to a restoring action in the direction opposite to the force. The movable member controls load-indicating means as a result of its displacement.Type: GrantFiled: September 29, 1978Date of Patent: September 16, 1980Inventor: Francois Simon
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Patent number: 4171639Abstract: The hollow rotating component such as a pulley, toothed wheel, drum and the like is mounted on a stationary hollow coaxial component in the form of a ring. The ring is coupled to a stationary support by means of a rigid mechanical part so arranged as to ensure that the internal space which is common to both components is left completely unobstructed and also given freedom of access. A detector or transducer for measuring deformations is mounted between the ring and the support.Type: GrantFiled: August 17, 1978Date of Patent: October 23, 1979Inventor: Francois Simon
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Patent number: 4054055Abstract: The invention provides a device for indicating the maximum permissible loads of a lifting appliance wherein a series of potentiometers are adjusted according to the variation of one parameter and control another potentiometer which is adjusted according to a second parameter, and means for assigning reference voltages to the series of potentiometers which means comprise, for each tapping, a series of polarisation circuits in parallel, each circuit providing a regulated voltage and controlled by a switch defining the instantaneous position of operation and simultaneously controlling all the polarisation circuits.Type: GrantFiled: August 6, 1976Date of Patent: October 18, 1977Assignee: PrecilecInventor: Francois Simon
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Patent number: 4015468Abstract: A device for measurement of the radial force sustained by a rotary organ, constituted by at least one detector of the deformation in the direction of the radial force to be measured in at least one of the elements constituted by two coaxial annular organs and a connecting one of the annular organs to a support.Type: GrantFiled: July 3, 1975Date of Patent: April 5, 1977Inventor: Francois Simon