Patents by Inventor Francois Spertini

Francois Spertini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EBOLA VACCINE COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20210340185
    Abstract: Materials and methods for the prevention of Ebola virus are provided. This disclosure is related to vaccine compositions comprising one or more Ebola vims (EBOV) glycoproteins as well as methods of preventing an EBOV infection comprising administering such compositions. In particular, modified EBOV glycoproteins are provided that form trimers and induce an immune response.
    Type: Application
    Filed: August 28, 2019
    Publication date: November 4, 2021
    Inventors: Divor Kiseljak, Florian M. Wurm, Valentina Agnolon, Francois Spertini, Bruno Correia
  • Allergen peptide fragments and use thereof for treatment of birch pollen allergies
    Patent number: 9808503
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: November 7, 2017
    Assignee: ANERGIS S.A.
    Inventors: Francois Spertini, Blaise Corthesy
  • Allergen Peptide Fragments and Use Thereof for Treatment of Birch Pollen Allergies
    Publication number: 20160095899
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Application
    Filed: November 23, 2015
    Publication date: April 7, 2016
    Inventors: Francois Spertini, Blaise Corthesy
  • Allergen peptide fragments and use thereof for treatment of dust mite allergies
    Patent number: 9193773
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: November 24, 2015
    Assignee: ANERGIS S.A..
    Inventors: Francois Spertini, Blaise Corthesy
  • Contiguous overlapping peptides for treatment of ragweed pollen allergy
    Patent number: 9005627
    Abstract: Contiguous overlapping peptides (COPs) for the treatment of allergic patients by Specific Immunotherapy (SIT) are provided from the sequence of the major allergen of ragweed pollen Amb a 1. Such peptides while providing all potential T cell epitopes are devoid of the three-dimensional structure of the original allergen, therefore reducing their ability to bind IgE.
    Type: Grant
    Filed: June 26, 2012
    Date of Patent: April 14, 2015
    Assignee: Anergis S.A.
    Inventors: Christophe Reymond, Francois Spertini
  • ALLERGEN PEPTIDE FRAGMENTS AND USE THEREOF FOR TREATMENT OF DUST MITE ALLERGIES
    Publication number: 20140193444
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Application
    Filed: March 12, 2014
    Publication date: July 10, 2014
    Applicant: ANERGIS S.A.
    Inventors: Francois Spertini, Blaise Corthesy
  • Allergen peptide fragments and use thereof for treatment of dust mite allergies
    Patent number: 8703144
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Grant
    Filed: October 28, 2011
    Date of Patent: April 22, 2014
    Assignee: Anergis S.A.
    Inventors: Francois Spertini, Blaise Corthesy
  • CONTIGUOUS OVERLAPPING PEPTIDES FOR TREATMENT OF RAGWEED POLLEN ALLERGY
    Publication number: 20130004527
    Abstract: Contiguous overlapping peptides (COPs) for the treatment of allergic patients by Specific Immunotherapy (SIT) are provided from the sequence of the major allergen of ragweed pollen Amb a 1. Such peptides while providing all potential T cell epitopes are devoid of the three-dimensional structure of the original allergen, therefore reducing their ability to bind IgE.
    Type: Application
    Filed: June 26, 2012
    Publication date: January 3, 2013
    Applicant: ANERGIS S.A.
    Inventors: Christophe Reymond, Francois Spertini
  • Contiguous overlapping peptides for treatment of birch pollen allergy
    Patent number: 8343503
    Abstract: Contiguous overlapping peptides (COPs) for the treatment of allergic patients by Specific Immunotherapy (SIT) are provided from the sequence of the major allergen of birch pollen Bet v 1. Such peptides while providing all potential T cell epitopes are devoid of the 3D structure of the original allergen, therefore reducing their ability to bind IgE.
    Type: Grant
    Filed: February 9, 2010
    Date of Patent: January 1, 2013
    Assignee: Anergis S.A.
    Inventors: Christophe Reymond, Francois Spertini
  • ALLERGEN PEPTIDE FRAGMENTS AND USE THEREOF FOR TREATMENT OF DUST MITE ALLERGIES
    Publication number: 20120100167
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Application
    Filed: October 28, 2011
    Publication date: April 26, 2012
    Applicant: ANERGIS S.A.
    Inventors: Francois Spertini, Blaise Corthesy
  • Allergen peptide fragments and use thereof
    Patent number: 8075897
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: December 13, 2011
    Assignee: Anergis S.A.
    Inventors: Francois Spertini, Blaise Corthesy
  • Allergen peptide fragments and use thereof
    Patent number: 7923209
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: April 12, 2011
    Assignee: Anergis, S.A.
    Inventors: Francois Spertini, Blaise Corthesy
  • Contiguous Overlapping Peptides for Treatment of Birch Pollen Allergy
    Publication number: 20100203070
    Abstract: Contiguous overlapping peptides (COPs) for the treatment of allergic patients by Specific Immunotherapy (SIT) are provided from the sequence of the major allergen of birch pollen Bet v 1. Such peptides while providing all potential T cell epitopes are devoid of the 3D structure of the original allergen, therefore reducing their ability to bind IgE.
    Type: Application
    Filed: February 9, 2010
    Publication date: August 12, 2010
    Applicant: ANERGIS SA
    Inventors: Christophe Reymond, Francois Spertini
  • Allergen peptide fragments and use thereof
    Publication number: 20070110673
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Application
    Filed: September 14, 2005
    Publication date: May 17, 2007
    Inventors: Francois Spertini, Blaise Corthesy
  • Bee venom polypeptides and methods of use thereof
    Patent number: 6878376
    Abstract: The present invention provides novel protein named Api m 6. Api m 6 was identified in bee venom and is found in four isoforms, each about 8 kD. The purified Api m 6 can be used to modulate immune responses, e.g., in individuals hypersensitive to bee venom.
    Type: Grant
    Filed: June 18, 2002
    Date of Patent: April 12, 2005
    Assignee: Ecole Polytechnique Federale de Lausanne
    Inventor: Francois Spertini
  • Allergen peptide fragments and use thereof
    Publication number: 20040241178
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Application
    Filed: March 12, 2004
    Publication date: December 2, 2004
    Inventors: Francois Spertini, Blaise Corthesy
  • Bee venom polypeptides and methods of use thereof
    Patent number: 6780416
    Abstract: The present invention provides novel protein named Api m 6. Api m 6 was identified in bee venom and is found in four isoforms, each about 8 kD. The purified Api m 6 can be used to modulate immune responses, e.g., in individuals hypersensitive to bee venom.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: August 24, 2004
    Assignee: Ecole Polytechnique Federale de Lausanne
    Inventor: Francois Spertini
  • Novel bee venom polypeptides and methods of use thereof
    Publication number: 20040023291
    Abstract: The present invention provides novel protein named Api m 6. Api m 6 was identified in bee venom and is found in four isoforms, each about 8 kD. The purified Api m 6 can be used to modulate immune responses, e.g., in individuals hypersensitive to bee venom.
    Type: Application
    Filed: December 19, 2002
    Publication date: February 5, 2004
    Inventor: Francois Spertini
  • Novel bee venom polypeptides and methods of use thereof
    Publication number: 20030165514
    Abstract: The present invention provides novel protein named Api m 6. Api m 6 was identified in bee venom and is found in four isoforms, each about 8 kD. The purified Api m 6 can be used to modulate immune responses, e.g., in individuals hypersensitive to bee venom.
    Type: Application
    Filed: June 18, 2002
    Publication date: September 4, 2003
    Applicant: Ecole Polytechnique Federale de Lausanne, Direction de la plantification et de la Recherche
    Inventor: Francois Spertini