Patents by Inventor Francois Tchi Ho Yu

Francois Tchi Ho Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Functionalized microbubble embodiments for ultrasound-mediated treatment and methods of making and using the same
    Patent number: 11793863
    Abstract: Disclosed herein are embodiments of a functionalized microbubble designed for treating and/or preventing vascular obstructions, including microvascular obstructions. The functionalized microbubble embodiments comprise a microbubble that can be activated upon exposure to ultrasound and further that has a lipid-based shell that is attached to an exteriorly-attached therapeutically active agent, such as a thrombolytic agent. Also disclosed herein are embodiments of a method for making and using the functionalized microbubble embodiments.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: October 24, 2023
    Assignees: University of Pittsburgh—Of the Commonwealth System of Higher Education, UPMC
    Inventors: John J. Pacella, Xucai Chen, Francois Tchi Ho Yu, Thiruganesh Ramasamy, Stephen D'Auria
  • FUNCTIONALIZED MICROBUBBLE EMBODIMENTS FOR ULTRASOUND-MEDIATED TREATMENT AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20200338172
    Abstract: Disclosed herein are embodiments of a functionalized microbubble designed for treating and/or preventing vascular obstructions, including microvascular obstructions. The functionalized microbubble embodiments comprise a microbubble that can be activated upon exposure to ultrasound and further that has a lipid-based shell that is attached to an exteriorly-attached therapeutically active agent, such as a thrombolytic agent. Also disclosed herein are embodiments of a method for making and using the functionalized microbubble embodiments.
    Type: Application
    Filed: April 24, 2020
    Publication date: October 29, 2020
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, UPMC
    Inventors: John J. Pacella, Xucai Chen, Francois Tchi Ho Yu, Thiruganesh Ramasamy, Stephen D'Auria