Patents by Inventor Francoise Bono

Francoise Bono has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A DBAIT MOLECULE IN COMBINATION WITH KRAS INHIBITOR FOR THE TREATMENT OF CANCER
    Publication number: 20230235327
    Abstract: The present invention relates to the combination of a Dbait molecule with a KRAS inhibitor for treating cancer.
    Type: Application
    Filed: June 4, 2021
    Publication date: July 27, 2023
    Inventors: WAEL JDEY, FRANÇOISE BONO
  • A DBAIT MOLECULE IN COMBINATION WITH KINASE INHIBITOR FOR THE TREATMENT OF CANCER
    Publication number: 20220143049
    Abstract: The present invention relates to the combination of a Dbait molecule with a protein kinase inhibitor for treating cancer.
    Type: Application
    Filed: March 19, 2020
    Publication date: May 12, 2022
    Inventors: FRANÇOISE BONO, GILLES FAVRE, OLIVIER CALVAYRAC
  • NEW CONJUGATED NUCLEIC ACID MOLECULES AND THEIR USES
    Publication number: 20220054524
    Abstract: The present invention relates to new nucleic acid molecules of therapeutic interest, in particular for use in the treatment of cancer.
    Type: Application
    Filed: December 20, 2019
    Publication date: February 24, 2022
    Inventors: BRIAN SPROAT, CHRISTELLE ZANDANEL, FRANÇOISE BONO, ALEXANDRE SIMON
  • A DBAIT MOLECULE AGAINST ACQUIRED RESISTANCE IN THE TREATMENT OF CANCER
    Publication number: 20200407720
    Abstract: The invention relates to a method for delaying and/or preventing development of cancer resistant to a cancer therapy agent in a patient based on administration of a Dbait molecule.
    Type: Application
    Filed: March 12, 2019
    Publication date: December 31, 2020
    Inventors: FRANÇOISE BONO, WAEL JDEY, MARIE DUTREIX
  • FGF-receptor agonist dimeric compounds
    Patent number: 9120819
    Abstract: FGF receptor agonist compounds corresponding to the general formula: M1-L-M2 are disclosed in which M1 and M2, which may be identical or different, each represent, independently of one another, a monomer unit M, and L represents a linker group, wherein the monomer unit is of the general formula I.
    Type: Grant
    Filed: July 11, 2008
    Date of Patent: September 1, 2015
    Assignee: SANOFI
    Inventors: Francoise Bono, Nathalie Guillo, Jean-Pierre Maffrand, Pierre Fons, Jacob-Alsboek Olsen, Gilles Anne-Archard
  • (Heterocycle/condensed piperidine)-(piperazinyl)-1-alkanone or (heterocycle/condensed pyrrolidine)-(piperazinyl)-1-alkanone derivatives and use thereof as p75 inhibitors
    Patent number: 8957211
    Abstract: The disclosure relates to (heterocycle-fused piperidine)-(piperazinyl)-1-alkanone derivatives and (heterocycle-fused pyrrolidine)-(piperazinyl)-1-alkanone derivatives of formula (I): wherein A, W, R2 and n are as defined in the disclosure, to the method of preparation thereof and the therapeutic use thereof.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: February 17, 2015
    Assignee: Sanofi
    Inventors: Marco Baroni, Francoise Bono, Sandrine Delbary-Gossart, Valentina Vercesi
  • (heterocycle/tetrahydropyridine)-(piperazinyl)-1-alcanone and (heterocycle/dihydropyrrolidine)-(piperazinyl)-1-alcanone derivatives, and use thereof as p75 inhibitors
    Patent number: 8906924
    Abstract: The disclosure relates to (heterocycle-tetrahydropyridine)(piperazinyl)-1-alkanone and (heterocycle-dihydropyrrolidine)(piperazinyl)-1-alkanone derivatives of formula (I): wherein A, B, m, n, W, and R2 are as defined in the disclosure; to the methods of preparing said derivatives, and to the therapeutic uses thereof.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: December 9, 2014
    Assignee: Sanofi
    Inventors: Marco Baroni, Francoise Bono, Sandrine Delbary-Gossart, Valentina Vercesi
  • NOVEL (HETEROCYCLE/CONDENSED PIPERIDINE)-(PIPERAZINYL)-1-ALKANONE OR (HETEROCYCLE/CONDENSED PYRROLIDINE)-(PIPERAZINYL)-1-ALKANONE DERIVATIVES AND USE THEREOF AS p75 INHIBITORS
    Publication number: 20140038946
    Abstract: The disclosure relates to (heterocycle-fused piperidine)-(piperazinyl)-1-alkanone derivatives and (heterocycle-fused pyrrolidine)-(piperazinyl)-1-alkanone derivatives of formula (I): wherein A, W, R2 and n are as defined in the disclosure, to the method of preparation thereof and the therapeutic use thereof.
    Type: Application
    Filed: October 8, 2013
    Publication date: February 6, 2014
    Applicant: SANOFI
    Inventors: Marco BARONI, Francoise BONO, Sandrine DELBARY-GOSSART, Valentina VERCESI
  • Imidazo[1,5-a]pyridine derivatives, method for preparing same and pharmaceutical compositions containing same
    Patent number: 8633216
    Abstract: The invention concerns compounds of formula I, a method for preparing said compounds, pharmaceutical compositions containing same and the therapeutic uses thereof.
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: January 21, 2014
    Assignee: Sanofi
    Inventors: Chantal Alcouffe, Alain Badorc, Francoise Bono, Marie-Francoise Bordes
  • Derivatives of 7 alkynyl-1,8 naphthyridones, preparation method thereof and use of same in therapeutics
    Patent number: 8586602
    Abstract: The disclosure relates to method of treating a disease in which VEGFR-3 is involved, comprising administering a therapeutically effective amount of a compound of the formula wherein R1, R2, R3, and R4 are as defined in the disclosure, to compositions containing them, to processes for preparing them, and to their use in therapeutics.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: November 19, 2013
    Assignee: Sanofi
    Inventors: Antoine Alam, Francoise Bono, Oliver Duclos, Gary McCort
  • NOVEL (HETEROCYCLE/TETRAHYDROPYRIDINE)-(PIPERAZINYL)-1-ALCANONE AND (HETEROCYCLE/DIHYDROPYRROLIDINE)-(PIPERAZINYL)-1-ALCANONE DERIVATIVES, AND USE THEREOF AS p75 INHIBITORS
    Publication number: 20130303520
    Abstract: The disclosure relates to (heterocycle-tetrahydropyridine)(piperazinyl)-1-alkanone and (heterocycle-dihydropyrrolidine)(piperazinyl)-1-alkanone derivatives of formula (I): wherein A, B, m, n, W, and R2 are as defined in the disclosure; to the methods of preparing said derivatives, and to the therapeutic uses thereof.
    Type: Application
    Filed: July 18, 2013
    Publication date: November 14, 2013
    Inventors: Marco BARONI, Francoise BONO, Sandrine DELBARY-GOSSART, Valentina VERCESI
  • (Heterocycle/condensed piperidine)-(piperazinyl)-1-alkanone or (heterocycle/condensed pyrrolidine)-(piperazinyl)-1-alkanone derivatives and use thereof as p75 inhibitors
    Patent number: 8580790
    Abstract: The disclosure relates to (heterocycle-fused piperidine)-(piperazinyl)-1-alkanone derivatives and (heterocycle-fused pyrrolidine)-(piperazinyl)-1-alkanone derivatives of formula (I): wherein A, W, R2 and n are as defined in the disclosure, to the method of preparation thereof and the therapeutic use thereof.
    Type: Grant
    Filed: June 7, 2012
    Date of Patent: November 12, 2013
    Assignee: Sanofi
    Inventors: Marco Baroni, Francoise Bono, Sandrine Delbary-Gossart, Valentina Vercesi
  • (Heterocycle/tetrahydropyridine)-(piperazinyl)-1-alcanone and (heterocycle/dihydropyrrolidine)-(piperazinyl)-1-alcanone derivatives, and use thereof as p75 inhibitors
    Patent number: 8518947
    Abstract: The disclosure relates to (heterocycle-tetrahydropyridine)(piperazinyl)-1-alkanone and (heterocycle-dihydropyrrolidine)(piperazinyl)-1-alkanone derivatives of formula (I): wherein A, B, m, n, W, and R2 are as defined in the disclosure; to the methods of preparing said derivatives, and to the therapeutic uses thereof.
    Type: Grant
    Filed: June 7, 2012
    Date of Patent: August 27, 2013
    Assignee: Sanofi
    Inventors: Marco Baroni, Francoise Bono, Sandrine Delbary-Gossart, Valentina Vercesi
  • Derivatives of (bridged piperazinyl)-1-alkanone and use thereof as p75 inhibitors
    Patent number: 8519143
    Abstract: The present invention relates to derivatives of ((phenyl)-3,6-dihydropyridin-1-yl)(bridged piperazinyl)-1-alkanone derivatives and ((phenyl)-2,5-dihydropyrrol-1-yl) (bridged piperazinyl)-1-alkanone corresponding to Formula (I): in which the variables are as defined herein, to the preparation thereof and to the therapeutic use thereof.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: August 27, 2013
    Assignee: Sanofi
    Inventors: Marco Baroni, Francoise Bono, Sandrine Delbary-Gossart
  • Derivatives of 7-alkynyl-1,8-naphthyridones, preparation method thereof and use of same in therapeutics
    Patent number: 8470847
    Abstract: The disclosure relates to 7-alkynyl-1,8-naphthyridones of formula (I): wherein R1, R2, R3, and R4 are as defined in the disclosure, to compositions containing them, to processes for preparing them, and to their use in therapeutics.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: June 25, 2013
    Assignee: Sanofi
    Inventors: Antoine Alam, Sandrine Biscarrat, Isabelle Blanc, Françoise Bono, Olivier Duclos, Gary Mccort
  • DERIVATIVES OF 2-OXOALKYL-1-PIPERAZIN-2-ONE, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME
    Publication number: 20120289518
    Abstract: The present invention relates to derivatives of 4-{2-[phenyl-3,6-dihydropyridin-1-yl]-2-oxoalkyl}-1-piperazin-2-one and 4-{2-[phenyl-2,5-dihydropyrrol-1-yl]-2-oxoalkyl}-1-piperazin-2-one having general formula (I): in which A, B, m, R3 and n are as defined herein. The invention also relates to the preparation thereof and to the therapeutic use thereof.
    Type: Application
    Filed: July 24, 2012
    Publication date: November 15, 2012
    Applicant: SANOFI
    Inventors: Marco BARONI, Francoise BONO, Sandrine DELBARY-GOSSART
  • NOVEL (HETEROCYCLE/TETRAHYDROPYRIDINE)-(PIPERAZINYL)-1-ALCANONE AND (HETEROCYCLE/DIHYDROPYRROLIDINE)-(PIPERAZINYL)-1-ALCANONE DERIVATIVES, AND USE THEREOF AS p75 INHIBITORS
    Publication number: 20120245150
    Abstract: The disclosure relates to (heterocycle-tetrahydropyridine)(piperazinyl)-1-alkanone and (heterocycle-dihydropyrrolidine)(piperazinyl)-1-alkanone derivatives of formula (I): wherein A, B, m, n, W, and R2 are as defined in the disclosure; to the methods of preparing said derivatives, and to the therapeutic uses thereof.
    Type: Application
    Filed: June 7, 2012
    Publication date: September 27, 2012
    Applicant: SANOFI
    Inventors: Marco BARONI, Françoise BONO, Sandrine DELBARY-GOSSART, Valentina VERCESI
  • NOVEL (HETEROCYCLE/CONDENSED PIPERIDINE)-(PIPERAZINYL)-1-ALKANONE OR (HETEROCYCLE/CONDENSED PYRROLIDINE)-(PIPERAZINYL)-1-ALKANONE DERIVATIVES AND USE THEREOF AS p75 INHIBITORS
    Publication number: 20120245149
    Abstract: The disclosure relates to (heterocycle-fused piperidine)-(piperazinyl)-1-alkanone derivatives and (heterocycle-fused pyrrolidine)-(piperazinyI)-1-alkanone derivatives of formula (I): wherein A, W, R2 and n are as defined in the disclosure, to the method of preparation thereof and the therapeutic use thereof.
    Type: Application
    Filed: June 7, 2012
    Publication date: September 27, 2012
    Applicant: SANOFI
    Inventors: Marco BARONI, Françoise BONO, Sandrine DELBARY-GOSSART, Valentina VERCESI
  • DERIVATIVES OF 7 ALKYNYL-1,8 NAPHTHYRIDONES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS
    Publication number: 20120238598
    Abstract: The disclosure relates to method of treating a disease in which VEGFR-3 is involved, comprising administering a therapeutically effective amount of a compound of the formula wherein R1, R2, R3, and R4 are as defined in the disclosure, to compositions containing them, to processes for preparing them, and to their use in therapeutics.
    Type: Application
    Filed: June 1, 2012
    Publication date: September 20, 2012
    Applicant: SANOFI-AVENTIS
    Inventors: Antoine ALAM, Françoise BONO, Oliver DUCLOS, Gary MCCORT
  • DERIVATIVES OF (BRIDGED PIPERAZINYL)-1-ALKANONE AND USE THEREOF AS p75 INHIBITORS
    Publication number: 20120232280
    Abstract: The present invention relates to derivatives of ((phenyl)-3,6-dihydropyridin-1-yl)(bridged piperazinyl)-1-alkanone derivatives and ((phenyl)-2,5-dihydropyrrol-1-yl) (bridged piperazinyl)-1-alkanone corresponding to Formula (I): in which the variables are as defined herein, to the preparation thereof and to the therapeutic use thereof.
    Type: Application
    Filed: May 17, 2012
    Publication date: September 13, 2012
    Applicant: SANOFI-AVENTIS
    Inventors: Marco BARONI, Françoise BONO, Sandrine DELBARY-GOSSART