Patents by Inventor Francoise Chamouleau

Francoise Chamouleau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Coupled cofactor-dependent enzymatic reaction systems in aqueous media
    Patent number: 7632665
    Abstract: The present application relates to a reaction system in which chemically valuable compounds can be obtained in high enantiomer concentrations with the aid of a coupled enzymatically operating transformation process. The coupled enzymatic reaction system comprises a cofactor-dependent enzymatic transformation of an organic compound and an enzymatic regeneration of the cofactor, wherein the reaction system operates in aqueous solution with an amount of substrate above the solubility limit thereof. In the preferred embodiments, an alcohol dehydrogenase is the cofactor-dependent enzyme, and the regeneration of the cofactor (e.g. NADH or NADPH) is acheved by means of formate dehydrogenase.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: December 15, 2009
    Assignee: Evonik Degussa GmbH
    Inventors: Harald Gröger, Claudia Rollmann, Hendrik Hüsken, Helge Werner, Francoise Chamouleau, Chad Hagedorn, Karlheinz Drauz, Werner Hummel
  • Preparation of optically active alcohols with whole-cell catalysts
    Publication number: 20090258405
    Abstract: The present invention relates to a process for the preparation of optically active alcohols from ketones with the aid of whole-cell catalysts comprising an alcohol dehydrogenase and also an enzyme capable of cofactor regeneration, a substrate concentration of at least 500 mM of ketone being provided for the conversion and the conversion being carried out without the addition of an “external” cofactor.
    Type: Application
    Filed: June 9, 2005
    Publication date: October 15, 2009
    Applicant: DEGUSSA AG.
    Inventors: Harald Groeger, Oliver May, Claudia Rollmann, Francoise Chamouleau, Nicolas Orologas, Karlheinz Drauz
  • Method For Producing Primary Alcohols
    Publication number: 20080145904
    Abstract: The present invention relates to a process for the production of primary alcohols from aldehydes with the said of whole-cell catalysts or isolated enzymes. Employed are an alcohol dehydrogenase and an enzyme which is capable of regenerating the cofactor, where it is preferred to have a substrate concentration of >150 mM aldehyde for the conversion.
    Type: Application
    Filed: August 4, 2005
    Publication date: June 19, 2008
    Inventors: Harald Groger, Francoise Chamouleau, Chad Hagedorn
  • Coupled cofactor-dependent enzymatic reaction systems in aqueous media
    Publication number: 20060216801
    Abstract: The present application relates to a reaction system in which chemically valuable compounds can be obtained in high enantiomer concentrations with the aid of a coupled enzymatically operating transformation process. The coupled enzymatic reaction system comprises a cofactor-dependent enzymatic transformation of an organic compound and an enzymatic regeneration of the cofactor, wherein the reaction system operates in aqueous solution with an amount of substrate above the solubility limit thereof. In the preferred embodiments, an alcohol dehydrogenase is the cofactor-dependent enzyme, and the regeneration of the cofactor (e.g. NADH or NADPH) is acheved by means of formate dehydrogenase.
    Type: Application
    Filed: March 17, 2004
    Publication date: September 28, 2006
    Applicant: Degussa AG
    Inventors: Harald Groger, Claudia Rollmann, Hendrik Husken, Helge Werner, Francoise Chamouleau, Chad Hagedorn, Karlheinz Drauz, Werner Hummel