Patents by Inventor Francoise Estradier

Francoise Estradier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5760043
    Abstract: Compositions intended for use for retarding hair loss and for inducing and stimulating its growth, containing 2-aminopyrimidine 3-oxide derivatives, and new compounds derived from 2-aminopyrimidine 3-oxide.Composition for retarding hair loss and for inducing and stimulating its growth, containing at least one compound of formula: ##STR1## where R denotes H, alkyl or a ring of formula: ##STR2## X denotes ##STR3## with: R.sub.1 and R.sub.3 denote H, alkyl, optionally substituted, alkenyl, cycloalkyl, aralkyl or aryl of formula: ##STR4## where R.sub.9 and R.sub.10 denote H, alkyl, hydroxyl, alkoxy or halogen; or form a heterocycle with the nitrogen;R.sub.3 denotes alkyl, alkenyl, cycloalkyl, aralkyl, optionally substituted phenyl;R.sub.4 is identical to R.sub.3 ;Y denotes O or --OSO.sub.3.sup..crclbar. ;R' denotes H or ##STR5## R.sub.5 and R.sub.6 are alkyl; R.sub.7 and R.sub.8 denote H or alkyl;or its physiologically acceptable addition salts with acids.
    Type: Grant
    Filed: December 18, 1996
    Date of Patent: June 2, 1998
    Assignee: L'Oreal
    Inventors: Didier Dufetel, Francoise Estradier, Quintino Gaetani, Michel Hocquaux
  • Patent number: 5610302
    Abstract: Composition for retarding hair loss and for inducing and stimulating its growth, containing at least one compound of formula: ##STR1## where R denotes H, alkyl or a ring of formula: ##STR2## X denotes ##STR3## --OR.sub.3, --SR.sub.4 with: the remaining variables defined below in the body of the specification.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: March 11, 1997
    Assignee: L'Oreal
    Inventors: Didier Dufetel, Francoise Estradier, Quintino Gaetani, Michel Hocquaux
  • Patent number: 5438058
    Abstract: Pharmaceutical or cosmetic composition intended to be used, by topical application, for retarding hair loss and for inducing or stimulating hair growth, containing at least one compound of formula: ##STR1## where: R.sub.1 denotes H or C.sub.1 -C.sub.8 alkyl;R.sub.2 denotes C.sub.1 -C.sub.8 alkyl or NHR.sub.3, where R.sub.3 denotes H or --COOR.sub.4, where R.sub.4 denotes C.sub.1 -C.sub.4 alkyl;X denotes ##STR2## --OR.sub.9 or --SR.sub.10 ; R.sub.5 and R.sub.6 denote H, optionally substituted C.sub.1 -C.sub.12 alkyl, or C.sub.2 -C.sub.12 alkenyl, C.sub.3 -C.sub.10 cycloalkyl, aralkyl or aryl, or form, with N, a saturated or unsaturated heterocycle;R.sub.9 denotes optionally substituted C.sub.1 -C.sub.12 alkyl, or C.sub.2 -C.sub.12 alkenyl, C.sub.3 -C.sub.10 cycloalkyl, C.sub.7 -C.sub.12 aralkyl or phenyl, which may optionally be substituted;R.sub.10 is identical to R.sub.9 ; andY denotes O or OSO.sub.3.sup..crclbar. ;as well as its cosmetically or pharmaceutically acceptable acid addition salts.
    Type: Grant
    Filed: April 1, 1994
    Date of Patent: August 1, 1995
    Assignee: L'Oreal
    Inventors: Didier Dufetel, Francoise Estradier, Michel Hocquaux
  • Patent number: 4675130
    Abstract: A two-stage process for producing indoanilines includes oxidizing in a first stage a paraphenylene diamine to a quinone diimine and in a second stage condensing the said quinone diimine with a phenolic compound. The resulting indoanilines can be incorporated into a dye composition for keratinous fibers, especially, human hair.
    Type: Grant
    Filed: August 26, 1980
    Date of Patent: June 23, 1987
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4494953
    Abstract: This invention pertains to compounds suitable for dyeing keratin fibers, especially human hair. The compounds have the formula: ##STR1## or an acid addition salt thereof, in which formula R.sub.1 and R.sub.2 form, together with the nitrogen atom to which they are bonded, a morpholino or piperidino ring and R represents a hydrogen atom.This invention also pertains to compositions for dyeing keratin fibers, especially human hair, such composition containing the compounds set forth above and/or compounds of formula (I) wherein R.sub.1 represents a hydrogen atom, R.sub.2 represents a tetrahydrofurfuryl or methoxyethyl radical and R represents a hydrogen atom or a methyl radical, or an acid addition salt thereof.The invention also pertains to the method of using these compositions.
    Type: Grant
    Filed: January 15, 1981
    Date of Patent: January 22, 1985
    Assignee: L'Oreal
    Inventors: Andree Bugaut, Francoise Estradier
  • Patent number: 4361516
    Abstract: New dyestuffs are described for keratinic fibers which produce particularly luminous shades without the need for an oxidizing agent. These dyestuffs have the formula: ##STR1## or a tautomeric form thereof wherein each of R.sub.1 and R.sub.4, which may be identical or different, represents a member selected from hydrogen, halogen, alkyl having 1 to 6 carbon atoms, alkoxy having 1 to 6 carbon atoms, acylamino and ureido;each of R.sub.2 and R.sub.3, which may be identical or different, represents a member selected from hydrogen, halogen, alkyl having 1 to 6 carbon atoms, alkoxy having 1 to 6 carbon atoms, amino, N-alkylamino, N-(hydroxyalkyl)-amino, N-(carbamyl-alkyl)-amino, acylamino and ureido, each of said alkyls containing 1 to 6 carbon atoms;each of R.sub.5 and R.sub.6, which may be identical or different, represents a member selected from hydrogen, halogen, alkyl containing 1 to 6 carbon atoms and alkoxy containing 1 to 6 carbon atoms, with the proviso that when R.sub.5 and R.sub.
    Type: Grant
    Filed: October 6, 1976
    Date of Patent: November 30, 1982
    Assignee: Societe Anonyme dite: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4288622
    Abstract: Diphenylamine of the formula ##STR1## wherein R.sub.1 and R.sub.4 each independently represent a member selected from the group consisting of hydrogen, halogen, lower alkyl having 1-6 carbon atoms, lower alkoxy having 1-6 carbon atoms, amino, lower alkyl amino wherein the alkyl moiety has 1-6 carbon atoms, acylamino, lower carbamylalkyl amino wherein the alkyl moiety has 1-6 carbon atoms, lower hydroxyalkyl amino wherein the alkyl moiety has 1-6 carbon atoms, lower carbalkoxy amino wherein the alkoxy moiety has 1-6 carbon atoms and ureido;R.sub.2 and R.sub.3 each independently represent a member selected from the group consisting of hydrogen, halogen, lower alkyl having 1-6 carbon atoms, lower alkoxy having 1-6 carbon atoms, acylamino and ureido;R.sub.5 and R.sub.8 each independently represent a member selected from the group consisting of hydrogen, halogen, lower alkyl having 1-6 carbon atoms and lower alkoxy having 1-6 carbon atoms; andR.sub.6 and R.sub.
    Type: Grant
    Filed: November 12, 1976
    Date of Patent: September 8, 1981
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4263213
    Abstract: New compounds suitable for dyeing keratin fibres, especially human hair, are described. The compounds have the formula: ##STR1## or an acid addition salt thereof, in which formula either R.sub.1 and R.sub.2 form, together with the nitrogen atom to which they are bonded, a morpholino or piperidino ring and R represents a hydrogen atom, or R.sub.1 represents a hydrogen atom, R.sub.2 represents a furfuryl or methoxyethyl radical and R represents a hydrogen atom or a methyl radical.
    Type: Grant
    Filed: April 4, 1979
    Date of Patent: April 21, 1981
    Assignee: L'Oreal
    Inventors: Andree Bugaut, Francoise Estradier
  • Patent number: 4248591
    Abstract: Indoaniline of the formula ##STR1## wherein R.sub.1 represents hydrogen, halogen, alkyl or alkoxy; R.sub.2 and R.sub.3 represent alkyl; R.sub.4, R.sub.5 and R.sub.6 each independently represent hydrogen, halogen, alkyl, alkoxy, acylamino, ureido or carbalkoxyamino and R.sub.5 can also represent amino, alkylmaino, hydroxy alkylamino or carbamylalkylamino, the alkyl and alkoxy groups above being able to contain 1 to 6 carbon atoms and the acyl group from 2 to 7 carbon atoms with the condition that R.sub.5 does not represent hydrogen, chlorine, methyl or methoxy and when R.sub.5 represents acetylamino, R.sub.6 does not represent hydrogen; it being understood that the above compounds can be present in the tautomeric form of that represented by formula (I). The indoaniline is usefully employed in dye copositions for keratinic fibers, especially living human hair.
    Type: Grant
    Filed: May 30, 1979
    Date of Patent: February 3, 1981
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4246181
    Abstract: A two-stage process for producing indoanilines includes oxidizing in a first stage a paraphenylene diamine to a quinone diimine and in a second stage condensing the said quinone diimine with a phenolic compound. The resulting indoanilines can be incorporated into a dye composition for keratinous fibers, especially, human hair.
    Type: Grant
    Filed: May 30, 1978
    Date of Patent: January 20, 1981
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4233241
    Abstract: Diphenylamine which is N-monosubstituted in the 4'-position carries at least one acylamino group at the 2- or 6-position. The diphenylamine is usefully employed in a composition for dyeing keratinic fibers.
    Type: Grant
    Filed: April 19, 1979
    Date of Patent: November 11, 1980
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4222958
    Abstract: Diphenylamine of the formula ##STR1## wherein R.sub.1 and R.sub.4 each independently represent a member selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy, amino, lower alkyl amino, acylamino, lower carbamylalkyl amino, lower hydroxyalkyl amino, lower carbalkoxy amino and ureido;R.sub.2 and R.sub.3 each independently represent a member selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy, acylamino and ureido;R.sub.5 represents a member selected from the group consisting of hydrogen, halogen, lower alkyl and lower alkoxy;R.sub.6 represents a member selected from the group consisting of lower hydroxyalkyl, lower amino alkyl, lower acylamino alkyl, lower mesylamino alkyl, lower carbamylalkyl, lower sulfoalkyl, lower piperidinoalkyl, lower morpholinoalkyl, lower mono alkyl lower amino alkyl and lower dialkyl lower amino alkyl; andR.sub.
    Type: Grant
    Filed: May 17, 1977
    Date of Patent: September 16, 1980
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4221729
    Abstract: Indoaniline of the formula ##STR1## wherein R.sub.1 represents hydrogen, halogen, alkyl or alkoxy; R.sub.2 and R.sub.3 represent alkyl; R.sub.4, R.sub.5 and R.sub.6 each independently represent hydrogen, halogen, alkyl, alkoxy, acylamino, ureido or carbalkoxyamino and R.sub.5 can also represent amino, alkylamino, hydroxyalkylamino or carbamylalkylamino, the alkyl and alkoxy groups above being able to contain 1 to 6 carbon atoms and the acyl group from 2 to 7 carbon atoms with the condition that R.sub.5 does not represent hydrogen, chlorine, methyl or methoxy and when R.sub.5 represents acetylamino, R.sub.6 does not represent hydrogen; it being understood that the above compounds can be present in the tautomeric form of that represented by formula (I). The indoaniline is usefully employed in dye compositions for keratinic fibers, especially living human hair.
    Type: Grant
    Filed: May 28, 1976
    Date of Patent: September 9, 1980
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4200432
    Abstract: A hair dye composition comprising at least one oxidation dye and at least one diphenylamine of the formula ##STR1## wherein R.sub.1 and R.sub.4 each independently represent hydrogen, halogen, lower alkyl having 1-6 carbon atoms, lower alkoxy having 1-6 carbon atoms, acylamino or ureido;R.sub.2 and R.sub.3 each independently represent hydrogen, halogen, lower alkyl having 1-6 carbon atoms, lower alkoxy having 1-6 carbon atoms, amino, N-alkylamino wherein the alkyl has 1-6 carbon atoms, N-hydroxyalkylamino wherein the alkyl has 1-6 carbon atoms, acylamino, N-carbamylalkylamino wherein the alkyl has 1-6 carbon atoms or ureido;R.sub.5 represents hydrogen, halogen, lower alkyl having 1-6 carbon atoms or lower alkoxy having 1-6 carbon atoms;R.sub.6, R.sub.7 and R.sub.8, each independently represent hydrogen, halogen, lower alkyl having 1-6 carbon atoms or lower alkoxy having 1-6 carbon atoms;Y represents hydroxy or amino; andZ represents hydroxy or ##STR2## wherein R.sub.9 and R.sub.
    Type: Grant
    Filed: November 21, 1977
    Date of Patent: April 29, 1980
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4112229
    Abstract: Diphenylamines of the formula ##STR1## wherein R.sub.1 and R.sub.2 each independently represent hydrogen, halogen or lower alkyl containing 1-4 carbon atoms with at least one of R.sub.1 and R.sub.2 being other than hydrogen; R.sub.3, R.sub.4, R.sub.5, R.sub.6, and R.sub.7 each independently represent hydrogen or lower alkyl optionally substituted with hydroxy, carbamyl, piperidinyl or acylamino; R.sub.3 and R.sub.6 or R.sub.4 and R.sub.7 also optionally forming together with the carbon and nitrogen atoms to which they are attached, a dihydrooxazine or pyrroline heterocycle; and Z represents amino, acylamino or hydroxy; and the acid salts of said diphenylamines. These diphenylamines are usefully employed in cosmetic compositions for the hair including hair dye compositions and hair setting lotion compositions.
    Type: Grant
    Filed: May 18, 1977
    Date of Patent: September 5, 1978
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4093806
    Abstract: Indoaniline of the formula ##STR1## wherein R.sub.1 represents hydrogen, halogen, alkyl or alkoxy; R.sub.2 represents alkyl, hydroxyalkyl, carbamylalkyl, piperidinoalkyl, morpholinoalkyl, sulfoalkyl, dialkylaminoalkyl, acylaminoalkyl, (preferably acetylaminoalkyl or benzoylaminoalkyl) and mesylaminoalkyl;R.sub.3 represents hydroxyalkyl, carbamylalkyl, piperidonoalkyl, morpholinoalkyl, sulfoalkyl, dialkylaminoalkyl, acylaminoalkyl, (preferably acetylaminoalkyl or benzoylaminoalkyl), mesylaminoalkyl; or R.sub.2 and R.sub.3 together form with the nitrogen atom to which they are attached a heterocycle selected from piperidino or morpholino;R.sub.4, r.sub.5 and R.sub.6 each independently represents hydrogen, halogen, alkyl, alkoxy, acylamino, ureido or carbalkoxyamino, and R.sub.5 can also represent amino, alkylamino, hydroxyalkylamino or carbamylalkylamino. The alkyl and alkoxy groups above can contain from 1 to 6 carbon atoms and the acyl group can contain from 2 to 7 carbon atoms.
    Type: Grant
    Filed: May 20, 1977
    Date of Patent: June 6, 1978
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4093640
    Abstract: Indamine having the formula ##STR1## wherein R and R' each independently represent a member selected from the group consisting of hydrogen, lower alkyl having 1-4 carbon atoms, lower alkoxy having 1-4 carbon atoms, amino, acylamino wherein the acyl moiety has 1 to 4 carbon atoms and hydroxy, with the proviso that one, but not both of R and R' is said amino, acylamino or hydroxy; R.sub.1 and R.sub.2 each independently represent a member selected from the group consisting of lower alkyl having 1-4 carbon atoms and lower alkyl having 1-4 carbon atoms and substituted with a member selected from the group consisting of hydroxy, acylamino wherein the acyl moiety has 1 to 4 carbon atoms, carbamyl, piperidino, benzoylamino and alkylsulfonamido wherein the alkyl moiety has 1 to 4 carbon atoms; R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.
    Type: Grant
    Filed: June 23, 1976
    Date of Patent: June 6, 1978
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4067869
    Abstract: A process for producing indamine by condensing 2,6-diamino pyridine on a paraphenylene diamine or a benzoquinone diimine or a paranitroso N,N-dialkyl aniline. The resulting indamine can be incorporated into a dye composition for keratinic fibers, especially human hair.
    Type: Grant
    Filed: September 28, 1976
    Date of Patent: January 10, 1978
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4054147
    Abstract: Diphenylamine of the formula ##STR1## wherein R.sub.1 and R.sub.4 each independently represent a member selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy, amino, lower alkyl amino, acylamino, lower carbamylalkyl amino, lower hydroxyalkyl amino, lower carbalkoxy amino and ureido;R.sub.2 and R.sub.3 each independently represent a member selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy, acylamino and ureido;R.sub.5 represents a member selected from the group consisting of hydrogen, halogen, lower alkyl and lower alkoxy;R.sub.6 represents a member selected from the group consisting of lower hydroxyalkyl, lower amino alkyl, lower acylamino alkyl, lower mesylamino alkyl, lower carbamylalkyl, lower sulfoalkyl, lower piperidinoalkyl, lower morpholinoalkyl, lower mono alkyl lower amino alkyl and lower dialkyl lower amino alkyl; andR.sub.
    Type: Grant
    Filed: February 21, 1975
    Date of Patent: October 18, 1977
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier
  • Patent number: 4046786
    Abstract: Indoaniline of the formula ##STR1## wherein R.sub.1 represents hydrogen, halogen, alkyl or alkoxy;R.sub.2 represents alkyl, hydroxyalkyl, carbamylalkyl, piperidinoalkyl, morpholinoalkyl, sulfoalkyl, dialkylaminoalkyl, acylaminoalkyl, (preferably acetylaminoalkyl or benzoylaminoalkyl) and mesylaminoalkyl;R.sub.3 represents hydroxyalkyl, carbamylalkyl, piperidinoalkyl, morpholinoalkyl, sulfoalkyl, dialkylaminoalkyl, acylaminoalkyl, (preferably acetylaminoalkyl or benzoylaminoalkyl), mesylaminoalkyl; or R.sub.2 and R.sub.3 together form with the nitrogen atom to which they are attached a heterocycle selected from piperidino or morpholino;R.sub.4, r.sub.5 and R.sub.6 each independently represents hydrogen, halogen, alkyl, alkoxy, acylamino, ureido or carbalkoxyamino, and R.sub.5 can also represent amino, alkylamino, hydroxyalkylamino or carbamylalkylamino. The alkyl and alkoxy groups above can contain from 1 to 6 carbon atoms and the acyl group can contain from 2 to 7 carbon atoms.
    Type: Grant
    Filed: October 3, 1975
    Date of Patent: September 6, 1977
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Andree Bugaut, Francoise Estradier