Patents by Inventor Frank A. Lehmkuhl

Frank A. Lehmkuhl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5-Hydroxyl-1,2,3-triazole-4-carboxamide nucleoside
    Patent number: 3948885
    Abstract: A 5-hydroxy-1,2,3-triazole-4-carboxamide nucleoside, related to the C-nucleoside pyrazomycin, is facilely synthesized by condensation of acyl-blocked ribofuranose with trimethylsilylated 5-hydroxy-1,2,3-triazole-4-carboxamide or, alternatively, by cycloaddition of suitably blocked .beta.-D-ribofuranosyl azide and the anion of ethyl malonamate, and demonstrated to exhibit antiviral properties. The triazole precursor of the former route, as well as certain of its novel salts, are also disclosed as potential antiviral agents.
    Type: Grant
    Filed: March 19, 1973
    Date of Patent: April 6, 1976
    Assignee: ICN Pharmaceuticals, Inc.
    Inventors: Joseph T. Witkowski, Roland K. Robins, Frank A. Lehmkuhl