Abstract: A system may measure, via a functional Near-Infrared Spectroscopy (fNIRS) device, a first set of measurements of a prefrontal cortex region of a patient. The system may perform, via a transcranial magnetic stimulation (TMS) device, TMS treatment to the prefrontal cortex region for therapeutic effect. The fNIRS device may measure a second set of measurements of the prefrontal cortex region. The system includes a processor to determine an applied dosing of the TMS treatment based on the first set of measurements and/or the second set of measurements. The system may output control feedback to the TMS device or visualization to a display to adjust one or more parameters or localization of the TMS treatment based on the applied dosing. The system personalizes the treatment dosing of TMS more accurately over the prefrontal cortex by calibrating the dose to the prefrontal cortex based on measurements from the fNIRS device.

Abstract: A device may include a transcranial magnetic stimulation (TMS) device configured to generate a localized magnetic field waveform at a brain region. A device may include an acoustic controller configured to generate an audio waveform having at least one of rhythm, harmonic element, or melodic element synchronized to the localized magnetic field waveform. In various implementations, the brain region is a motor cortex of a patient. The device can evoke or produce neurostimulation effects through acoustic stimulation (e.g., music) through classical (or Pavlovian) conditioning paired in combination with synchronized transcranial magnetic stimulation output. The device can be used to extend the effects of neuromodulation, thus reducing the burden of in-patient visits (for procedural neurostimulation), reducing battery life demand of implanted devices, or simply improving the patient experience with achieving benefits (i.e., by listening to music versus unnatural sensory sensations with neurostimulation).

Abstract: Methods for determining whether the brain activity of a human subject in response to a stimulus of interest or question of interest is characteristic of a state of interest, such as a deceptive state or a truthful state, are disclosed. Some methods include the use of control questions, including truthful control questions and deceptive control questions, to provide bases for comparison for responses to stimuli of interest or questions of interest. In some methods, brain maps are generated and compared. Also disclosed are systems for detecting deception by measuring brain activity.

Abstract: Methods for determining whether the brain activity of a human subject in response to a stimulus of interest or question of interest is characteristic of a state of interest, such as a deceptive state or a truthful state, are disclosed. Some methods include the use of control questions, including truthful control questions and deceptive control questions, to provide bases for comparison for responses to stimuli of interest or questions of interest. In some methods, brain maps are generated and compared. Also disclosed are systems for detecting deception by measuring brain activity.

Abstract: Methods for determining whether the brain activity of a human subject in response to a stimulus of interest or question of interest is characteristic of a state of interest, such as a deceptive state or a truthful state, are disclosed. Some methods include the use of control questions, including truthful control questions and deceptive control questions, to provide bases for comparison for responses to stimuli of interest or questions of interest. Some methods include the use of differences between two states, such as a deceptive state and a truthful state. In some methods, brain maps are generated and compared. Also disclosed are systems for detecting deception by measuring brain activity.