Abstract: The instant disclosure is generally related to compositions and methods for obtaining and constructing Bacillus licheniformis host cells (e.g., protein production host cells, cell factories) having increased protein production capabilities. Certain embodiments of the disclosure are directed to efficient genetic modifications of B. licheniformis cells and the subsequent selection of such B. licheniformis cells having increased protein production capabilities. Certain other embodiments of the disclosure are generally related to methods and compositions for producing/obtaining auxotrophic B. licheniformis cells, wherein certain other embodiments of the disclosure are directed to methods and compositions for restoring prototrophy in auxotrophic B. licheniformis cells, and expressing genes of interest (GOIs) in such restored prototrophy B. licheniformis cells.

Abstract: According to an aspect, there is provided a handheld device (2) for applying energy pulses to skin (17) of a subject to perform a treatment operation as the handheld device is moved across the skin, the handheld device comprising: an aperture (6) that is to be placed adjacent to the skin; at least one energy source (8) for generating an energy pulse and for providing the energy pulse through the aperture to perform the treatment operation on 5 skin adjacent the aperture, wherein the at least one energy source has a minimum pulse repetition period following the generation of an energy pulse before a subsequent energy pulse can be generated; a first skin property sensor (14) for measuring a skin property and for outputting a first measurement signal representing measurements of the skin property at a first sensing position (24), wherein the skin property is a property that changes in response to the application of an energy pulse to the skin, and wherein the first sensing position is in front of the aperture re

Abstract: According to an aspect, there is provided a method for determining a value of a skin parameter for skin of a subject. The method comprises receiving (510) a first sensor signal that is output by a first light sensor that is arranged to receive light emitted by a first light source after interaction of the emitted light with the skin. The first sensor signal is output while the first light source operates according to a first duty cycle to intermittently emit the light, and the emitted light has a first central wavelength.

Abstract: A light-emitting device (100) is disclosed. The light-emitting device (100) comprises a plurality of light-emitting elements (135) or light sources and a power module (120) adapted to selectively convey, supply or provide electrical power to the light-emitting elements (135). The power module (120) may be dimensioned such as to be able to power only a proper subset of the light-emitting elements (135) of the light-emitting device (100) at a given time, the subset having a maximum number of light-emitting elements (135) included therein with respect to the number of light-emitting elements (135) included in the all subsets of the light-emitting elements (135) of the light-emitting device (100).

Abstract: According to an aspect, there is provided a treatment device for performing a treatment operation on or to a subject. The treatment device comprises: an optical diffuser arranged on the treatment device such that an outer surface of the optical diffuser is proximate to, or in contact with, skin of the subject when the treatment device is to be used to perform the treatment operation; and an imaging unit for obtaining one or more images using light passing through the optical diffuser into the treatment device; wherein the treatment device is further configured for providing one or more images to a processing unit for determination of whether the treatment device is in contact with the skin.

Abstract: The present application relates to a cold plasma device (1) for treating skin (5). The cold plasma device (1) comprises a cold plasma generator (3) adapted to generate cold plasma that produces reactive species for treating said skin (5), and a manipulator (10) adapted to manipulate said skin (5) to increase exposure of bacteria on said skin to said reactive species during use of the device.

Abstract: A light-emitting device (100) is disclosed. The light-emitting device (100) comprises a plurality of light-emitting elements (135) or light sources and a power module (120) adapted to selectively convey, supply or provide electrical power to the light-emitting elements (135). The power module (120) may be dimensioned such as to be able to power only a proper subset of the light-emitting elements (135) of the light-emitting device (100) at a given time, the subset having a maximum number of light-emitting elements (135) included therein with respect to the number of light-emitting elements (135) included in the all subsets of the light-emitting elements (135) of the light-emitting device (100).

Abstract: A computer-implemented method of determining a location of a personal care device with respect to a skin surface of a subject, the personal care device being configured to perform a personal care treatment to the skin when in contact with the skin surface. The method includes receiving data representative of a measured degree of curvature of the skin surface within a first region of the skin surface of the subject, with which the personal care device is in contact; determining, by comparing the measured degree of curvature with curvature information for a plurality of regions of the skin surface of the subject contained in a database, an indication of a location of the first region of the skin surface on the subject; and performing, based on the determined indication of the location of the first region, an action in respect of the personal care device. A processing apparatus, a system, a personal care device, and a computer program product are also disclosed.

Abstract: There is provided an apparatus comprising: a base substrate and a component substrate having at least two electronic components arranged thereon. At least one aperture is formed through an entire thickness of the component substrate. The at least one aperture is formed in an interspace between the at least two electronic components. The component substrate is coupled to the base substrate using a solder joint. Each of the at least two electronic components may comprise a light emitting diode element. A method of manufacturing an apparatus is also disclosed.

Abstract: According to an aspect, there is provided a handheld device (2) for applying energy pulses to skin (17) of a subject to perform a treatment operation as the handheld device is moved across the skin, the handheld device comprising: an aperture (6) that is to be placed adjacent to the skin; at least one energy source (8) for generating an energy pulse and for providing the energy pulse through the aperture to perform the treatment operation on 5 skin adjacent the aperture, wherein the at least one energy source has a minimum pulse repetition period following the generation of an energy pulse before a subsequent energy pulse can be generated; a first skin property sensor (14) for measuring a skin property and for outputting a first measurement signal representing measurements of the skin property at a first sensing position (24), wherein the skin property is a property that changes in response to the application of an energy pulse to the skin, and wherein the first sensing position is in front of the aperture re

Abstract: There is provided a device (100) for use in determining a hydration level and/or lipid level of skin (200). The device (100) comprises at least two electrodes (102) configured to provide an electrical signal to the skin (200) and a spacer (104) arranged such that the at least two electrodes (102) provide the electrical signal to the skin (200) at different penetration depths (106, 108). The device (100) also comprises a detector (110) configured to measure a response received from the skin (200) at the different penetration depths (106, 108) for use in determining the hydration level and/or lipid level of the skin (200).

Abstract: A method of biostimulating phototherapy is provided. The method comprises illuminating a subject's body portion with light having a first wavelength in the range of 600-900 nm. The method further comprises the step of at least one of reducing and preventing hyperthermia of the body portion by illuminating the body portion with light having a second wavelength which is at least one of in the range of 400-600 nm and in the range of 900-2500 nm. Further, a phototherapy device is provided which comprises a first light source and a second light source. The first light source is configured to emit light having a first wavelength which is in the range of 600-900 nm. The second light source is configured to emit light having a second wavelength which is at least one of in the range of 400-600 nm and in the range of 900-2500 nm. At least a portion of the device is a patch which is formed for conforming to at least part of the body portion.

Abstract: According to an aspect, there is provided a hand-held skin treatment device (2) for applying light to skin of a subject to perform a treatment operation.

Abstract: A method, an apparatus, and a computer program product for wireless communication are provided. According to one embodiment, a method of operating a device includes: selecting a signal format from a plurality of signal formats, each of the plurality of signal formats corresponding to a respective coding and modulation scheme of a plurality of coding and modulation schemes; and sending a request for random access to a base station according to the selected signal format.

Abstract: There is provided an apparatus comprising: a base substrate and a component substrate having at least two electronic components arranged thereon. At least one aperture is formed through an entire thickness of the component substrate. The at least one aperture is formed in an interspace between the at least two electronic components. The component substrate is coupled to the base substrate using a solder joint. Each of the at least two electronic components may comprise a light emitting diode element. A method of manufacturing an apparatus is also disclosed.

Abstract: The disclosure relates to an active part for an electrical machine, wherein the active part includes: a plurality of teeth and a plurality of coils, wherein a coil of the plurality of coils is arranged on each of the teeth, wherein each of the coils has a plurality of prefabricated push-on elements arranged adjacent to one another on the tooth and enclose the tooth in parts, and wherein each of the coils has a plurality of prefabricated connecting elements each for electrically connecting two adjacent push-on elements.

Abstract: The present application relates to a cold plasma device (13) for treating a surface (6) with cold plasma. The device (13) has a cold plasma generator (14) adapted to generate cold plasma that produces reactive species for treating the surface (6). The device (13) also includes a treatment head (5) that is positionable relative to the surface (6) such that the reactive species are imparted toward the surface (6) during treatment. The device (13) is also provided with an air flow generator (8) to generate an air flow over the surface (6) and a controller (9) configured to control operation of the air flow generator (8) to generate an air flow over the surface (6) after the treatment has been completed such that remaining by-products of the cold plasma are dissipated.

Abstract: An electric motor equipped with a transmission unit in the form of a planetary gear transmission is provided. The planetary gear transmission has a sun gear, planetary gears, and a ring gear, which are coupled to one another via corresponding toothings. The sun gear is coupled directly to a shaft of the electric motor and is fastened thereto. The planetary gears or axles thereof are retained on a bearing plate of the electric motor. The ring gear is rotatably mounted on the housing of the electric motor or is fastened to the housing of the electric motor. A common feature is that parts of the transmission are retained on the housing of the electric motor and not on a separate housing or another component of the transmission unit.

Abstract: Methods, systems, and devices are described for wireless communication at a UE. A user equipment (UE) may perform an initial access procedure to establish a connection with a serving cell. The UE may then arrange a regular transmission schedule with the serving cell including a discontinuous transmission (DTX) cycle and an acknowledgement schedule. The UE may enter a low power mode and refrain from any transmission during the a sleep interval of the DTX cycle. The UE may then wake up and transmit a message to the serving cell after the sleep interval without performing another access procedure. The UE may perform another access procedure to transmit at times not covered by the regular transmission schedule. For example, if an acknowledgement (ACK) for the message isn't received, the UE may perform another access procedure for retransmission.

Abstract: Systems and methods for determining one or more temperatures within a phototherapy blanket use or include one or more temperature sensors and a set of light sources to determine a temperature of a subject undergoing phototherapy within the phototherapy blanket and estimate a core temperature of the subject based on, at least, the temperature. The phototherapy blanket may include a thicker region having a higher thermal insulation than one or more other regions of the phototherapy blanket. By virtue of measuring the temperature at or near the thicker region, the uncertainty in the relation between a temperature and the subject's core temperature may be reduced, for more accurate temperature determination within the phototherapy blanket.