Patents by Inventor Frank Antonicelli

Frank Antonicelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bifunctional peptide
    Patent number: 9115212
    Abstract: The bifunctional peptide is capable of activating collagen synthesis and inhibiting the production of matrix metallo-proteinases. The peptide has a sequence including three peptide parts A, B and C. The first peptide part A corresponds to a hexapeptide repeated at least three times, the part A being capable of bonding to a receptor elastin-binding protein in order to stimulate collagen synthesis. The second peptide part B corresponds to a tetrapeptide capable of acting as a competitive inhibitor of urokinase protease and of being cleaved by said protease. The third peptide part C corresponds to a tripeptide occupying at least one active site of the matrix metallo-proteinases in order to enable inhibition of the proteinases. The present invention further concerns a cosmetic and/or pharmaceutical composition incorporating the bifunctional peptide.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: August 25, 2015
    Assignees: REGENTIS INTERNATIONAL, UNIVERSITE DE REIMS CHAMPAGNE ARDENNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: William Hornebeck, Joan Attia, Sandrine Lorimier, Frank Antonicelli
  • BIFUNCTIONAL PEPTIDE
    Publication number: 20150031633
    Abstract: The bifunctional peptide is capable of activating collagen synthesis and inhibiting the production of matrix metallo-proteinases. The peptide has a sequence including three peptide parts A, B and C. The first peptide part A corresponds to a hexapeptide repeated at least three times, the part A being capable of bonding to a receptor elastin-binding protein in order to stimulate collagen synthesis. The second peptide part B corresponds to a tetrapeptide capable of acting as a competitive inhibitor of urokinase protease and of being cleaved by said protease. The third peptide part C corresponds to a tripeptide occupying at least one active site of the matrix metallo-proteinases in order to enable inhibition of the proteinases. The present invention further concerns a cosmetic and/or pharmaceutical composition incorporating the bifunctional peptide.
    Type: Application
    Filed: January 31, 2013
    Publication date: January 29, 2015
    Inventors: William Hornebeck, Joan Attia, Sandrine Lorimier, Frank Antonicelli