Patents by Inventor Frank Baas

Frank Baas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240016926
    Abstract: Isolated monoclonal antibodies that bind to human complement component C6 and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic methods for using the antibodies.
    Type: Application
    Filed: February 14, 2023
    Publication date: January 18, 2024
    Inventors: Frank Baas, Marc A. Van Dijk
  • Patent number: 11590222
    Abstract: Isolated monoclonal antibodies that bind to human complement component C6 and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic methods for using the antibodies.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: February 28, 2023
    Assignee: Regenesance B.V.
    Inventors: Frank Baas, Marc A. Van Dijk
  • Publication number: 20220227884
    Abstract: The present invention relates to methods and medicaments used for treating conditions that require axonal regeneration, e.g. in mammals affected by injury or disease of the central or peripheral nervous system. The medicaments used in these methods facilitate axonal regeneration by inhibition of the complement system. Conditions requiring axonal regeneration that may be treated in accordance with the invention include physical injuries as well as neurodegenerative disorders of the peripheral or central nervous system.
    Type: Application
    Filed: April 5, 2022
    Publication date: July 21, 2022
    Inventors: Frank BAAS, Valeria RAMAGLIA
  • Publication number: 20210060157
    Abstract: Isolated monoclonal antibodies that bind to human complement component C6 and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic methods for using the antibodies.
    Type: Application
    Filed: May 1, 2020
    Publication date: March 4, 2021
    Inventors: Frank BAAS, Marc A. VAN DIJK
  • Patent number: 10675348
    Abstract: Isolated monoclonal antibodies that bind to human complement component C6 and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic methods for using the antibodies.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: June 9, 2020
    Assignee: Regenesance B.V.
    Inventors: Frank Baas, Marc A. Van Dijk
  • Publication number: 20180022824
    Abstract: The present invention relates to methods and medicaments used for treating conditions that require axonal regeneration, e.g. in mammals affected by injury or disease of the central or peripheral nervous system. The medicaments used in these methods facilitate axonal regeneration by inhibition of the complement system. Conditions requiring axonal regeneration that may be treated in accordance with the invention include physical injuries as well as neurodegenerative disorders of the peripheral or central nervous system.
    Type: Application
    Filed: August 9, 2017
    Publication date: January 25, 2018
    Inventors: Frank BAAS, Valeria RAMAGLIA
  • Publication number: 20180015162
    Abstract: Isolated monoclonal antibodies that bind to human complement component C6 and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic methods for using the antibodies.
    Type: Application
    Filed: June 16, 2017
    Publication date: January 18, 2018
    Inventors: Frank BAAS, Marc A. VAN DIJK
  • Publication number: 20150211003
    Abstract: Disclosed are antagonists designed to inhibit or block expression of a mammalian complement such as complement component 6 (C6). The invention has a wide range of uses including use in the preparation of a medicament for the enhancement of nerve regeneration following acute or chronic nerve damage in a mammal. Additional applications include use in the treatment of multiple sclerosis either alone or in combination with another drug.
    Type: Application
    Filed: March 12, 2014
    Publication date: July 30, 2015
    Applicant: REGENESANCE B.V.
    Inventors: Frank BAAS, Kees FLUITER
  • Patent number: 9089555
    Abstract: Disclosed are antagonists designed to inhibit or block expression of a mammalian complement such as complement component 6 (C6). The invention has a wide range of uses including use in the preparation of a medicament for the enhancement of nerve regeneration following acute or chronic nerve damage in a mammal. Additional applications include use in the treatment of multiple sclerosis either alone or in combination with another drug.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: July 28, 2015
    Assignee: Regenesance B.V.
    Inventors: Frank Baas, Kees Fluiter
  • Publication number: 20140301982
    Abstract: Disclosed are antagonists designed to inhibit or block expression of a mammalian complement such as complement component 6 (C6). The invention has a wide range of uses including use in the preparation of a medicament for the enhancement of nerve regeneration following acute or chronic nerve damage in a mammal. Additional applications include use in the treatment of multiple sclerosis either alone or in combination with another drug.
    Type: Application
    Filed: March 12, 2014
    Publication date: October 9, 2014
    Applicant: REGENESANCE B.V.
    Inventors: Frank BAAS, Kees FLUITER
  • Publication number: 20140255395
    Abstract: The present invention relates to methods and medicaments used for treating conditions that require axonal regeneration, e.g. in mammals affected by injury or disease of the central or peripheral nervous system. The medicaments used in these methods facilitate axonal regeneration by inhibition of the complement system. Conditions requiring axonal regeneration that may be treated in accordance with the invention include physical injuries as well as neurodegenerative disorders of the peripheral or central nervous system.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 11, 2014
    Applicant: REGENESANCE B.V.
    Inventors: Frank BAAS, Valeria RAMAGLIA
  • Patent number: 8703136
    Abstract: The present invention relates to methods and medicaments used for treating conditions that require axonal regeneration, e.g. in mammals affected by injury or disease of the central or peripheral nervous system. The medicaments used in these methods facilitate axonal regeneration by inhibition of the complement system. Conditions requiring axonal regeneration that may be treated in accordance with the invention include physical injuries as well as neurodegenerative disorders of the peripheral or central nervous system.
    Type: Grant
    Filed: October 10, 2007
    Date of Patent: April 22, 2014
    Assignee: Regenesance B.V.
    Inventors: Frank Baas, Valeria Ramaglia
  • Patent number: 8703730
    Abstract: Disclosed are antagonists designed to inhibit or block expression of a mammalian complement such as complement component 6 (C6). The invention has a wide range of uses including use in the preparation of a medicament for the enhancement of nerve regeneration following acute or chronic nerve damage in a mammal. Additional applications include use in the treatment of multiple sclerosis either alone or in combination with another drug.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: April 22, 2014
    Assignee: Regenesance B.V.
    Inventors: Frank Baas, Kees Fluiter
  • Publication number: 20110171176
    Abstract: Disclosed are antagonists designed to inhibit or block expression of a mammalian complement such as complement component 6 (C6). The invention has a wide range of uses including use in the preparation of a medicament for the enhancement of nerve regeneration following acute or chronic nerve damage in a mammal. Additional applications include use in the treatment of multiple sclerosis either alone or in combination with another drug.
    Type: Application
    Filed: July 10, 2009
    Publication date: July 14, 2011
    Applicant: Academisch Ziekenhuis Bij de Universiteit Van Amsterdam
    Inventors: Frank Baas, Kees Fluiter
  • Publication number: 20100143344
    Abstract: The present invention relates to methods and medicaments used for treating conditions that require axonal regeneration, e.g. in mammals affected by injury or disease of the central or peripheral nervous system. The medicaments used in these methods facilitate axonal regeneration by inhibition of the complement system. Conditions requiring axonal regeneration that may be treated in accordance with the invention include physical injuries as well as neurodegenerative disorders of the peripheral or central nervous system.
    Type: Application
    Filed: October 10, 2007
    Publication date: June 10, 2010
    Inventors: Frank Baas, Valeria Ramaglia