Patents by Inventor Frank BAMBERG

Frank BAMBERG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREFILLED SYRINGE AND METHOD OF PREPARING A PREFILLED SYRINGE
    Publication number: 20230310681
    Abstract: A method of preparing a prefilled syringe (1), comprises (i) obtaining a syringe barrel (11) having an open end (111) and a tip (112) with an orifice (113) essentially opposite to the open end (111), and a needle adaptor cap (12) assembled on the tip (112) of the syringe barrel, wherein the needle adaptor cap (12) has a rubber element (121) tightly sealing the orifice (113) of the tip (112) of the syringe barrel (11) and the syringe barrel (11) together with the needle adaptor cap (12) assembled on the tip (112) of the syringe barrel (11) is sterilized by a first sterilizing comprising a main step of exposing the syringe barrel (11) together with the needle adaptor cap (12) assembled on the tip (112) of the syringe barrel (11) to ethylene oxide for about 5 hours to about 60 hours at a relative humidity of about 40% to about 100% and at a temperature of about 30° C. to about 60° C.
    Type: Application
    Filed: June 6, 2023
    Publication date: October 5, 2023
    Inventors: Markus HEMMINGER, Ulla GRAUSCHOPF, Frank BAMBERG, Mayumi BOWEN, Robert MÜLLER, Flora FELSOVALYI, Denny CHRISTENSEN
  • Syringe and method of preparing syringe
    Patent number: 11771843
    Abstract: A syringe (18) has a longitudinal body (28) with an interior (228) in which a pharmaceutical substance is arranged, a needle connected to one longitudinal end of the body (228) and a rigid needle shield (38) encasing the needle. The rigid needle shield (38) is essentially water vapour tight. The syringe (18) according to the invention allows for preventing needle clogging and, thus, proper provision of pharmaceuticals, particularly by subcutaneous, intramuscular or ocular injection.
    Type: Grant
    Filed: February 18, 2022
    Date of Patent: October 3, 2023
    Assignees: HOFFMANN-LA ROCHE INC., GENENTECH, INC.
    Inventors: Frank Bamberg, Heather L. Flores, Robert Müller, Elisabeth Schaible, Edward Schwarb, Lionel Vedrine, Kewei Yang, Mathieu Rigollet, Pierre Goldbach, Baboo Dushyantsingh Goordyal, Ivy Lin, Florian Wildenhahn
  • Prefilled syringe and method of preparing a prefilled syringe
    Patent number: 11738106
    Abstract: A method of preparing a prefilled syringe is disclosed that includes obtaining a syringe barrel and a needle adaptor cap assembled on the tip of the syringe barrel, wherein the needle adaptor cap has a rubber element tightly sealing the orifice of the tip of the syringe barrel and the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel is sterilized by a first sterilizing. Filling a drug substance into an interior of the syringe barrel and sealing the interior of the syringe barrel. Packaging the syringe barrel with a rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel. Providing a second external surface sterilizing of the packaged syringe barrel with the rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: August 29, 2023
    Assignees: F. HOFFMANN-LA ROCHE AG, GENENTECH, INC.
    Inventors: Markus Hemminger, Ulla Grauschopf, Frank Bamberg, Mayumi Bowen, Robert Müller, Flora Felsovalyi, Denny Christensen
  • SYRINGE AND METHOD OF PREPARING SYRINGE
    Publication number: 20220203041
    Abstract: A syringe (18) has a longitudinal body (28) with an interior (228) in which a pharmaceutical substance is arranged, a needle connected to one longitudinal end of the body (228) and a rigid needle shield (38) encasing the needle. The rigid needle shield (38) is essentially water vapour tight. The syringe (18) according to the invention allows for preventing needle clogging and, thus, proper provision of pharmaceuticals, particularly by subcutaneous, intramuscular or ocular injection.
    Type: Application
    Filed: February 18, 2022
    Publication date: June 30, 2022
    Inventors: Frank BAMBERG, Heather L. FLORES, Robert MÜLLER, Elisabeth SCHAIBLE, Edward SCHWARB, Lionel VEDRINE, Kewei YANG, Mathieu RIGOLLET, Pierre GOLDBACH, Baboo Dushyantsingh GOORDYAL, Ivy LIN, Florian WILDENHAHN
  • PREFILLED SYRINGE AND METHOD OF PREPARING A PREFILLED SYRINGE
    Publication number: 20200297919
    Abstract: A method of preparing a prefilled syringe is disclosed that includes obtaining a syringe barrel and a needle adaptor cap assembled on the tip of the syringe barrel, wherein the needle adaptor cap has a rubber element tightly sealing the orifice of the tip of the syringe barrel and the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel is sterilized by a first sterilizing. Filling a drug substance into an interior of the syringe barrel and sealing the interior of the syringe barrel. Packaging the syringe barrel with a rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel. Providing a second external surface sterilizing of the packaged syringe barrel with the rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel.
    Type: Application
    Filed: September 28, 2018
    Publication date: September 24, 2020
    Inventors: Markus HEMMINGER, Ulla GRAUSCHOPF, Frank BAMBERG, Mayumi BOWEN, Robert MÜLLER, Flora FELSOVALYI, Denny CHRISTENSEN
  • PREFILLED SYRINGE AND METHOD OF PREPARING A PREFILLED SYRINGE
    Publication number: 20200282130
    Abstract: A method of preparing a prefilled syringe is disclosed that includes obtaining a syringe barrel and a needle adaptor cap assembled on the tip of the syringe barrel, wherein the needle adaptor cap has a rubber element tightly sealing the orifice of the tip of the syringe barrel and the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel is sterilized by a first sterilizing. Filling a drug substance into an interior of the syringe barrel and sealing the interior of the syringe barrel. Packaging the syringe barrel with a rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel. Providing a second external surface sterilizing of the packaged syringe barrel with the rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel.
    Type: Application
    Filed: September 28, 2018
    Publication date: September 10, 2020
    Inventors: Markus HEMMINGER, Ulla GRAUSCHOPF, Frank BAMBERG, Mayumi BOWEN, Robert MÜLLER, Flora FELSOVALYI, Denny CHRISTENSEN
  • SYRINGE AND METHOD OF PREPARING SYRINGE
    Publication number: 20170333641
    Abstract: A syringe (18) has a longitudinal body (28) with an interior (228) in which a pharmaceutical substance is arranged, a needle connected to one longitudinal end of the body (228) and a rigid needle shield (38) encasing the needle. The rigid needle shield (38) is essentially water vapour tight. The syringe (18) according to the invention allows for preventing needle clogging and, thus, proper provision of pharmaceuticals, particularly by subcutaneous, intramuscular or ocular injection.
    Type: Application
    Filed: October 30, 2015
    Publication date: November 23, 2017
    Inventors: Frank BAMBERG, Heather L. FLORES, Robert MÜLLER, Elisabeth SCHAIBLE, Edward SCHWARB, Lionel VEDRINE, Kewei YANG, Mathieu RIGOLLET, Pierre GOLDBACH, Baboo Dushyantsingh GOORDYAL, Ivy LIN, Florian WILDENHAHN