Patents by Inventor Frank Bretschneider
Frank Bretschneider has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10646444Abstract: The invention provides pellet for use as a core for a pharmaceutical dosage form having an inner and an outer zone where the inner zone includes a biologically active agent and said outer zone includes a layer formed by applying a substantially dry, free flowing inert powder which forms a non-tacky surface when placed in contact with water. The invention also provides a process for making pharmaceutical pellets where the core or at least one a layer on the core is formed by (a) contacting powder particles, adhering them to each other and compacting the adhered pellets by a rolling movement, wherein the degree of densification is controlled by the rolling movement; and (b) feeding a sufficient amount of a substantially dry, free flowing inert powder which forms a non-tacky surface when placed in contact with water to provide on said particles an outer zone including a layer formed from said substantially dry, free flowing inert powder.Type: GrantFiled: April 7, 2016Date of Patent: May 12, 2020Assignee: Nortec Development Associates, Inc.Inventors: Orapin Rubino, David M. Jones, Frank Bretschneider, Peter Frankhauser, Armin Prasch
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Patent number: 10039717Abstract: The invention provides pellet for use as a core for a pharmaceutical dosage form having an inner and an outer zone where the inner zone includes a biologically active agent and said outer zone includes a layer formed by applying a substantially dry, free flowing inert powder which forms a non-tacky surface when placed in contact with water. The invention also provides a process for making pharmaceutical pellets where the core or at least one a layer on the core is formed by (a) contacting powder particles, adhering them to each other and compacting the adhered pellets by a rolling movement, wherein the degree of densification is controlled by the rolling movement; and (b) feeding a sufficient amount of a substantially dry, free flowing inert powder which forms a non-tacky surface when placed in contact with water to provide on said particles an outer zone including a layer formed from said substantially dry, free flowing inert powder.Type: GrantFiled: March 14, 2014Date of Patent: August 7, 2018Assignee: Nortec Development Associates, Inc.Inventors: Orapin P. Rubino, David M. Jones, Frank Bretschneider, Peter Frankhauser, Armin Prasch
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Publication number: 20160220491Abstract: The invention provides pellet for use as a core for a pharmaceutical dosage form having an inner and an outer zone where the inner zone includes a biologically active agent and said outer zone includes a layer formed by applying a substantially dry, free flowing inert powder which forms a non-tacky surface when placed in contact with water. The invention also provides a process for making pharmaceutical pellets where the core or at least one a layer on the core is formed by (a) contacting powder particles, adhering them to each other and compacting the adhered pellets by a rolling movement, wherein the degree of densification is controlled by the rolling movement; and (b) feeding a sufficient amount of a substantially dry, free flowing inert powder which forms a non-tacky surface when placed in contact with water to provide on said particles an outer zone including a layer formed from said substantially dry, free flowing inert powder.Type: ApplicationFiled: April 7, 2016Publication date: August 4, 2016Applicant: Nortec Development Associates Inc.Inventors: Orapin Rubino, David M. Jones, Frank Bretschneider, Peter Frankhauser, Armin Prasch
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Publication number: 20140255594Abstract: The invention provides pellet for use as a core for a pharmaceutical dosage form having an inner and an outer zone where the inner zone includes a biologically active agent and said outer zone includes a layer formed by applying a substantially dry, free flowing inert powder which forms a non-tacky surface when placed in contact with water. The invention also provides a process for making pharmaceutical pellets where the core or at least one a layer on the core is formed by (a) contacting powder particles, adhering them to each other and compacting the adhered pellets by a rolling movement, wherein the degree of densification is controlled by the rolling movement; and (b) feeding a sufficient amount of a substantially dry, free flowing inert powder which forms a non-tacky surface when placed in contact with water to provide on said particles an outer zone including a layer formed from said substantially dry, free flowing inert powder.Type: ApplicationFiled: March 14, 2014Publication date: September 11, 2014Applicant: Nortec Development Associates Inc.Inventors: Orapin P. Rubino, David M. Jones, Frank Bretschneider, Peter Frankhauser, Armin Prasch
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Patent number: 6984449Abstract: The invention relates to pellets and a production process therefor. Pellets comprise at least one oily component, which is either an active component alone or comprises such an active component. The aim of the invention is to ensure that such active components can be provided at elevated concentration in a long-term stable form for subsequent administration or further processing using such inventive pellets. The at least one oily oxidation-sensitive or else readily volatile active component is distributed homogeneously and discretely in a matrix and encapsulated without a core with at least one water-soluble polysaccharide as filmforming agent. The individual pellets have a respective particle size of at least 100 ?m, preferably of at least 300 ?m.Type: GrantFiled: December 18, 2003Date of Patent: January 10, 2006Assignee: IPC Process Center GmbH & Co.Inventors: Karola Bretschneider, legal representative, Wolfgang Kempe, Marcel Minor, Marijke Adamse, Frank Bretschneider, deceased
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Patent number: 6968681Abstract: The invention relates to a device and a method for the aftertreatment of exhaust gases from combustion engines, in particular from internal combustion engines. The device according to the invention and the method are intended to be of simple construction, should be inexpensive to produce and operate and should have less adverse effect on the flow conditions in the exhaust gas stream. To achieve this object, at least one region which is filled with beads is provided in the exhaust-gas stream, the beads preferably being hollow beads. The exhaust gas from the combustion engine is passed through this region, and it is possible to achieve particle agglomeration with simultaneous separation of these particles. In addition, further regions which are filled with metal fibers may follow the at least one region filled with beads, and the exhaust gas is additionally passed through these further regions.Type: GrantFiled: November 17, 2001Date of Patent: November 29, 2005Assignees: Glatt Systemtechnik GmbH, Hochschule fuer Technik und Wirtschaft Dresden, Fraunhofer-Gesellschaft zur Foerderung der Angewandten Forschung E.V.Inventors: Guenter Stephani, Olaf Andersen, Gennadi Zikoridse, Ernstwendelin Bach, Frank Bretschneider
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Patent number: 6828026Abstract: The invention relates to hollow balls having shells comprising a sintered inorganic material, such as metals, metal oxides or ceramic, and to methods for producing lightweight structural components using such hollow balls. According to the object of the invention, the application area is to be widened, processing to form structural components is to be made technologically simpler and the properties of the hollow balls and of the structural components produced therewith are to be improved for specific applications. For this purpose, an additional solid functional layer is formed on a shell on the hollow balls. The functional-layer material can then be made able to flow and plastically and/or elastically deformed as a result of a physical and/or chemical treatment.Type: GrantFiled: October 9, 2002Date of Patent: December 7, 2004Assignees: Glatt Systemtechnik Dresden GmbH, Fraunhofer-Gesellschaft Zur Foerderung der Angewandten Forschung E.V.Inventors: Frank Bretschneider, Herbert Stephan, Juergen Brueckner, Guenter Stephani, Lothar Schneider, Ulf Waag, Olaf Andersen, Paul Hunkemoeller
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Publication number: 20040201116Abstract: The invention relates to pellets and a production process therefor. Pellets comprise at least one oily component, which is either an active component alone or comprises such an active component. The aim of the invention is to ensure that such active components can be provided at elevated concentration in a long-term stable form for subsequent administration or further processing using such inventive pellets. The at least one oily oxidation-sensitive or else readily volatile active component is distributed homogeneously and discretely in a matrix and encapsulated without a core with at least one water-soluble polysaccharide as filmforming agent. The individual pellets have a respective particle size of at least 100 &mgr;m, preferably of at least 300 &mgr;m.Type: ApplicationFiled: December 18, 2003Publication date: October 14, 2004Inventors: Frank Bretschneider, Wolfgang Kempe, Marcel Minor, Marijke Adamse, Karola Bretschneider
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Publication number: 20040185111Abstract: The invention provides pellet for use as a core for a pharmaceutical dosage form having an inner and an outer zone where the inner zone includes a biologically active agent and said outer zone includes a layer formed by applying a substantially dry, free flowing inert powder which forms a non-tacky surface when placed in contact with water. The invention also provides a process for making pharmaceutical pellets where the core or at least one a layer on the core is formed by (a) contacting powder particles, adhering them to each other and compacting the adhered pellets by a rolling movement, wherein the degree of densification is controlled by the rolling movement; and (b) feeding a sufficient amount of a substantially dry, free flowing inert powder which forms a non-tacky surface when placed in contact with water to provide on said particles an outer zone including a layer formed from said substantially dry, free flowing inert powder.Type: ApplicationFiled: December 4, 2003Publication date: September 23, 2004Inventors: Orapin P. Rubino, David M. Jones, Frank Bretschneider, Karola Bretschneider, Peter Frankhauser, Armin Prasch
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Publication number: 20040121154Abstract: The invention relates to pellets and a production process therefor. Pellets comprise at least one oily component, which is either an active component alone or comprises such an active component. The aim of the invention is to ensure that such active components can be provided at elevated concentration in a long-term stable form for subsequent administration or further processing using such inventive pellets. The at least one oily oxidation-sensitive or else readily volatile active component is distributed homogeneously and discretely in a matrix and encapsulated without a core with at least one water-soluble polysaccharide as film forming agent. The individual pellets have a respective particle size of at least 100 &mgr;m, preferably of at least 300 &mgr;m.Type: ApplicationFiled: April 17, 2003Publication date: June 24, 2004Inventors: Frank Bretschneider, Wolfgang Kempe, Marcel Minor, Marijke Adamse
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Publication number: 20040065079Abstract: The invention relates to a device and a method for the aftertreatment of exhaust gases from combustion engines, in particular from internal combustion engines. The device according to the invention and the method are intended to be of simple construction, should be inexpensive to produce and operate and should have less adverse effect on the flow conditions in the exhaust gas stream. To achieve this object, at least one region which is filled with beads is provided in the exhaust-gas stream, the beads preferably being hollow beads. The exhaust gas from the combustion engine is passed through this region, and it is possible to achieve particle agglomeration with simultaneous separation of these particles. In addition, further regions which are filled with metal fibers may follow the at least one region filled with beads, and the exhaust gas is additionally passed through these further regions.Type: ApplicationFiled: November 4, 2003Publication date: April 8, 2004Inventors: Guenter Stephani, Olaf Andersen, Gennadi Zikoridse, Ernstwendelin Bach, Frank Bretschneider
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Publication number: 20030104147Abstract: The invention relates to hollow balls having shells comprising a sintered inorganic material, such as metals, metal oxides or ceramic, and to methods for producing lightweight structural components using such hollow balls. According to the object of the invention, the application area is to be widened, processing to form structural components is to be made technologically simpler and the properties of the hollow balls and of the structural components produced therewith are to be improved for specific applications. For this purpose, an additional solid functional layer is formed on a shell on the hollow balls. The functional-layer material can then be made able to flow and plastically and/or elastically deformed as a result of a physical and/or chemical treatment.Type: ApplicationFiled: October 9, 2002Publication date: June 5, 2003Inventors: Frank Bretschneider, Herbert Stephan, Juergen Brueckner, Guenter Stephani, Lothar Schneider, Ulf Waag, Olaf Andersen, Paul Hunkemoeller
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Publication number: 20030077473Abstract: According to the invention, the shaped bodies are comprised of at least one heavy metal, preferably Fe, Ni, Co, Sn, Mo or W which can be reduced from a corresponding metallic compound at a temperature of less than 1 500° C. The shaped bodies have an outer diameter ranging from 0.05 to 0.5 mm, and a diameter-to-wall thickness ratio of 0.5 to 3%.Type: ApplicationFiled: October 8, 2002Publication date: April 24, 2003Inventors: Frank Bretschneider, Herbert Stephan, Juergen Brueckner, Guentor Stephani, Lothar Schneider, Ulf Waag
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Patent number: 6449869Abstract: Device and method for drying a pourable products. The device includes a rotor chamber in which a rotor is arranged with a vertical rotor axis. The rotor has a central horizontal surface and, at least in its radially outer third, a conical shell which is inclined to the axis of rotation by 20° to 70°, in such a way that the end face of the conical shell has the largest diameter and is located at the top. The conical shell has, at least partially, sheet-like gas passages in the form of perforations or screens. The method for drying pourable products provides for dry gas to be fed in a sheet like manner to the products to be dried during the radially peripheral circulation of the products without the products being swirled up and being exposed to unacceptable compressive, concussive and/or frictional loads.Type: GrantFiled: May 24, 2000Date of Patent: September 17, 2002Assignees: Glatt Systemtechnik Dresden GmbH, KWS Saat AGInventors: Frank Bretschneider, Bruno Peter, Jürgen Brückner
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Patent number: 6354728Abstract: Device for producing a pourable product with a guide vane therein and method for using the device. The device includes a rotor chamber in which a rotor is arranged with a vertical rotor axis. The rotor has, at least in its radially outer third, the shape of a conical shell. Guide vanes for circulating starting materials or the product are arranged statically on an inner wall of the rotor chamber above the plane of the upper edge of the rotor. The guide vanes have, in cross section to the rotor axis, essentially the shape of a segment of a circle or spiral. The inner ends of the guide vanes lie approximately in the middle part of the rotor radius. The conical shell may have at least partially sheet-like gas passages in the form of perforations or screens. The device is used for producing pourable products.Type: GrantFiled: May 24, 2000Date of Patent: March 12, 2002Assignees: Glatt Systemtechnik Dresden GmbH, Kws Saat AGInventors: Frank Bretschneider, Bruno Peter, Jürgen Bruckner
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Patent number: 6076836Abstract: A sealing system for a closing flap in a passage orifice of a facility where, in a coupled position, the closing flap rests in parallel against an identical closing flap on another facility in a sealing plane and cooperates therewith in such a way that the interiors of the two facilities are connected to one another. In a closed position, the individual closing flap has a seal on its circumference for sealing off an associated passage orifice. At least one of the two cooperating closing flaps has, on its circumference, a groove which is delimited on both sides by annular legs. A first leg delimits the groove toward the interior of the respective facility and extends near to the sealing surface of the passage orifice. The second leg is radially shortened relative to the first leg.Type: GrantFiled: May 26, 1998Date of Patent: June 20, 2000Assignee: Glatt Systemtechnik Dresden GmbHInventors: Frank Bretschneider, Willibald Kuhnemund