Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives of Formula I, wherein the variables G, T, D, L, A, X, R1 and R2 are as described hereinabove, and their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

Abstract: Described herein are pyrrolo{2,3-d}pyrimidine derivatives, their use as Janus Kinase (JAK) inhibitors, and pharmaceutical compositions containing them.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: Systems, methods and devices for monitoring the location of mobile radio terminal users for the purpose of detecting when they approach within range of one or more target locations in order to trigger voice and/or data communications to or from the network or other mobile radio terminals.

Abstract: The invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof, thereof, wherein: G is a group of formula (II): and pharmaceutically acceptable salts, prodrugs, hydrates, or solvates, thereof, wherein A, B, L1-L4, A, B, R1-R4, and m are as defined herein. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and their use in treating a bacterial infection.

Abstract: Systems, methods, and processor-readable storage media are disclosed for collecting information pertaining to the configuration of one or more wireless networks and using this information in turn to estimate the location of mobile wireless devices associated with those networks. Certain embodiments of the present disclosure are directed to providing efficient systems and methods for collecting the information, which are responsive to the coverage or quality of the wireless network configuration information already stored in a network database.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: Methods and systems of updating a zone profile comprising obtaining a plurality of radio signal parameter measurements and, if the plurality of radio signal parameter measurements contains at least one measurement corresponding to a dominant element of the zone profile and if the plurality of radio signal parameter measurements contains at least one measurement corresponding to a candidate element (e.g., statistically unlikely element) of the zone profile, updating the profile by either adjusting an existing parameter value or by adding a new element to the zone profile corresponding to the candidate element.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives of formula I, wherein the variables G, T, D, L, R1, R2, R3 are as described herein, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections in a patient in need thereof.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: Systems, methods, and processor readable media for estimating the speed of a mobile radio terminal traveling on at least one road segment are disclosed. Certain embodiments are characterized by determining one or more routes through a road network that a mobile radio terminal could have traveled based on a sequence of wireless measurements from the mobile radio terminal. In addition, systems, methods, and processor readable media for collecting and transmitting radio communications network measurements from a mobile terminal for use in a system of estimating a traffic flow speed on road segments are disclosed. Certain embodiments are characterized by accumulating and communicating a plurality of wireless measurements to a traffic flow measurement server such that reporting of wireless measurements is minimized when the mobile radio terminal is stationary.

Abstract: Aspirators for inflating devices such as (but not limited to) aircraft evacuation slides and rafts are detailed. Housings of the aspirators may be made of wound filaments of composite materials, reducing their weight as compared to conventional metal structures. Such actions as reconfiguring and repositioning jet nozzles within the housings also contribute to enhancing performance of the aspirators.