Abstract: Disclosed is a method and an oral composition for treating CNS disorders. An embodiment of the invention comprises orally administering an allopregnanolone containing composition to a subject having a CNS disorder. Exemplary CNS disorders include sleep disorders, mood disorders, dysthymic disorders, bipolar disorders, anxiety disorders, stress disorders, compulsive disorders, schizophrenia spectrum disorders, convulsive disorders, memory disorders, cognition disorders, movement disorders, personality disorders, autism spectrum disorders, substance abuse disorders, dementia, pain, traumatic brain injury (TBI), vascular disease, withdrawal syndrome, and tinnitus. The composition and methods disclosed herein exhibit effective oral absorption/bioavailability.

Abstract: Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I and methods of preparing the same.

Abstract: Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I and methods of preparing the same.

Abstract: Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula 1 and methods of preparing the same.

Abstract: A spare tire carrier is provided. The spare tire carrier includes a mounting assembly and a support assembly that cooperate to carry a spare tire. The mounting assembly is configured for releaseably connecting the spare tire carrier to a vehicle. The support assembly is configured for supporting the spare tire regardless of whether the spare tire has a rim or is rimless. The spare tire carrier may also include a hinged bracket that allows the spare tire carrier to be placed in a down position to allow the driver to access engine components.

Abstract: A spare tire carrier is provided. The spare tire carrier includes a mounting assembly and a support assembly that cooperate to carry a spare tire. The mounting assembly is configured for releaseably connecting the spare tire carrier to a vehicle. The support assembly is configured for supporting the spare tire for regardless of whether the spare tire has a rim or is rimless. The spare tire carrier may also include a hinged bracket that allows the spare tire carrier to be placed in a down position to allow the driver to access engine components.

Abstract: Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I and methods of preparing the same.

Abstract: This application discloses a novel process for the preparation of 1,2-substituted 3,4-dioxo-1-cyclobutene compounds, which have utility, for example, in the treatment of CXC chemokine-mediated diseases, and intermediates useful in the synthesis thereof.

Abstract: Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I and methods of preparing the same.

Abstract: Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I and methods of preparing the same.

Abstract: A stand-alone battery monitoring system coupled to a battery product having a positive pole and a negative pole, a housing and an electronics package contained within the housing. A sensor is coupled to and communicates with the battery product and the controller. Multiple code segments form software on the controller, the software includes a code segment acquiring battery product data for voltage and internal temperature from the sensor, a segment filters the acquired battery product data into modified battery product data and processing the modified battery product data against stored parameters, a segment stores battery product data in the portion of memory and retains the battery product data to provide historical battery product data. A code segment compares the stored data against threshold levels and an indicator sends an alert if the code segment comparing the stored battery product data against threshold levels determines that data is beyond those levels.

Abstract: A vehicle battery product and a battery monitoring system communicating with a battery product having an at least one electronics module, the module having a controller, the controller having software and a computer readable storage media. An at least one sensor circuit senses the status of the battery product including a battery product voltage and a battery product temperature. Software modules in the battery monitoring system acquire battery product data such as the battery product voltage and the battery product temperature, filter the acquired battery product data into modified battery product data and process the modified battery product data against stored parameters through a lookup function on a variable event filter table resulting in an output that represents the state of charge or state of health of the battery. The acquired, filtered, modified and compared battery product data is stored to provide historical battery product data over the course of the life of the battery product.

Abstract: A method of controlling a multiple battery system in a vehicle electrical system is provided. The method steps include polling an at least one sensor in the multiple battery system monitoring the multiple battery system for an at least one reading and detecting an abnormal reading from said at least one sensor. And then communicating the results of said detection step to an operator or a Network Operations Center switching, upon a command from the operator, the Network Operations Center or a controller switching an at least one switch from a first of an at least two operating positions engaging a main battery to a second of an at least two operating positions engaging an at least one auxiliary battery. The system then confirms the operation of the vehicle electrical system and engages either the main battery or the auxiliary battery, but not both, to operate the vehicle electrical system.

Abstract: A remotely controllable multiple battery system for reliably supplying electrical energy to an electrical system, the remotely controllable multiple battery system receiving control signals from a remote control device, the remotely controllable multiple battery system having a remotely controlled controller. An at least one sensor that senses the condition of a main battery and an at least one controlled switching device coupled remotely to the controller and responding to a signal from the remote control device to the controller thereby switching from the main battery to an at least one auxiliary battery.

Abstract: A stand alone battery monitoring system coupled to a battery product having a positive pole and a negative pole having a housing, a battery monitoring electronics package contained within the housing, the electronics package having a controller with at least one of an at least one CPU, EEPROM(s), ADC(s), PWM(s), Digital Input(s), and Digital Output(s) and including a portion of memory for storage of data and software. A sensor is coupled to and communicates with the battery product and the controller, measuring at least a battery product voltage and a battery product temperature.

Abstract: A multiple battery system includes a battery housing, first and second batteries disposed in the battery housing, a one-way charging circuit, and at least one switching device. The battery housing includes at least one positive terminal and at least one negative terminal, which are electrically coupleable to an electrical system. Each battery includes respective positive and negative outputs. The negative output of each battery is electrically connected to the negative terminal(s) of the battery housing. The one-way charging circuit is electrically connected between the positive outputs of the two batteries and is configured to facilitate charging of, but prevent current flow from, the second battery when the first battery is supplying electrical energy to the electrical system. The switching device(s) is operable in at least two states to selectively electrically connect the positive terminal(s) of the battery housing to a selective one of the positive outputs of the two batteries.

Abstract: An auxiliary battery attachment apparatus, which is attachable to a first housing containing a first battery, includes a second housing, a second battery disposed within the second housing, positive and negative couplings, a one-way charging circuit, and at least one switching device. The coupling(s) are respectively coupleable to positive and negative terminal(s) of the first housing. The second housing includes positive and negative terminals, which are electrically coupleable to an electrical system. The charging circuit is electrically connected between the positive coupling(s) and a positive output of the second battery, and facilitates charging of, but prevents current flow from, the second battery when the first battery is supplying electrical energy to the electrical system. The switching device(s) is operable in at least two states to electrically connect the positive terminal(s) of the second housing to a selective one of the positive coupling(s) and the positive output of the second battery.

Abstract: Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-S[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I and methods of preparing the same.

Abstract: A method of operating a network for tracking and storing warranty information and metrics of a programmable battery and programming the programmable battery, the method comprising executing a diagnostic check of the programmable battery, storing sales or maintenance specific programming, activation, and configuration data for the programmable battery in a memory coupled to the programmable battery through at least one point of sale/point of maintenance device, searching the network for software updates and product enablement data for the programmable battery and communicating information stored in the memory to a database through the point of sale/point of maintenance device and the network.

Abstract: A tamper resistant programmable battery and warranty and metrics tracking network is provided having an at least one network comprising a warranty and metrics information tracking system and information storage device storing data regarding the tamper resistant programmable battery. An at least one electronics module is coupled to the tamper resistant programmable battery so as to deter removal or tampering and an at least one point of sale/point of maintenance device is in communication with the network and the tamper resistant programmable battery, whereby the tamper resistant programmable battery is enabled by the transfer of data from the at least one network to the tamper resistant programmable battery.