Patents by Inventor Frank C. P. Holstege

Frank C. P. Holstege has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dissecting the regulatory circuitry of a eukaryotic genome
    Publication number: 20030219721
    Abstract: A method of identifying cellular regulatory circuits which employ at least one component of a subcomplex of regulatory proteins within the RNA II polymerase holoenzyme which behaves as a signal processor for gene-specific regulators (at least one component of a eukaryotic transcription initiation apparatus) and of determining the set of components of the apparatus which are responsible for regulation of each gene and the set of genes which are coordinately controlled by each transcription factor.
    Type: Application
    Filed: May 27, 2003
    Publication date: November 27, 2003
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: Frank C. P. Holstege, Richard A. Young
  • Dissecting the regulatory circuitry of a eukaryotic genomei
    Patent number: 6653071
    Abstract: A method of identifying cellular regulatory circuits which employ at least one component of a subcomplex of regulatory proteins within the RNA II polymerase holoenzyme which behaves as a signal processor for gene-specific regulators (at least one component of a eukaryotic transcription initiation apparatus) and of determining the set of components of the apparatus which are responsible for regulation of each gene and the set of genes which are coordinately controlled by each transcription factor.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: November 25, 2003
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Frank C. P. Holstege, Richard A. Young