Patents by Inventor Frank Casper Tortella

Frank Casper Tortella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENDOTHELIAL-MONOCYTE ACTIVATING POLYPEPTIDE II (EMAP-II), A BIOMARKER FOR USE IN DIAGNOSIS AND TREATMENT OF BRAIN INJURY
    Publication number: 20150057193
    Abstract: A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP II) and comparing to a control. An increase of EMAP II indicates the presence of traumatic brain injury and a decrease of EMAP II indicates the presence of ischemic brain injury.
    Type: Application
    Filed: September 26, 2014
    Publication date: February 26, 2015
    Inventors: JITENDRA RAMANLAL DAVE, CHANGPING YAO, ANTHONY JOSEPH WILLIAMS, XI-CHUN MAY-LU, FRANK CASPER TORTELLA, KA-WANG KEVIN WAND, RONALD LAWRENCE HAYES
  • Endothelial monocyte activation polypeptide II, a biomarker for use in diagnosis and treatment of brain injury
    Publication number: 20110028349
    Abstract: A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP-II) and comparing to a control. An increase of EMAP-II indicates the presence of traumatic brain injury and a decrease of EMAP-II indicates the presence of ischemic brain injury.
    Type: Application
    Filed: August 19, 2010
    Publication date: February 3, 2011
    Inventors: Jitendra Ramanlal Dave, Changping Yao, Anthony Joseph Williams, Xi-Chun May, Frank Casper Tortella, Ka-Wang Kevin Wang, Ronald Lawrence Hayes
  • Endothelial-monocyte activating polypeptide II, a biomarker for use in diagnosis of brain injury
    Patent number: 7799536
    Abstract: A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP-II) and comparing to a control. An increase of EMAP-II indicates the presence of traumatic brain injury and a decrease of EMAP-II indicates the presence of ischemic brain injury. Detection of EMAP-II can be done in brain tissue, biofluids such as cerebrospinal fluid or blood (including plasma and serum).
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: September 21, 2010
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Jitendra Ramanlal Dave, Changping Yao, Anthony Joseph Williams, Xi-Chun May, Frank Casper Tortella, Ka-Wang Kevin Wang, Ronald Lawrence Hayes
  • Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate
    Patent number: 7714020
    Abstract: Aspects of this invention include the use of G-2MePE to treat patients with brain injury characterized by non-convulsive seizures. G-2MePE is useful in treating brain injuries caused by traumatic brain injury, stroke, hypoxia/ischemia and toxic injury.
    Type: Grant
    Filed: April 4, 2006
    Date of Patent: May 11, 2010
    Assignee: Neuren Pharmaceuticals Limited
    Inventors: Peter David Gluckman, Margaret Anne Brimble, Douglas Wilson, Frank Casper Tortella, Anthony Joseph Williams, Xi-Chun May Lu, Jed A. Hartings, Divina Gryder
  • Endothelial-monocyte activating polypeptide II, a biomarker for use in diagnosis and treatment of brain injury
    Publication number: 20090068691
    Abstract: A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP-II) and comparing to a control. An increase of EMAP-II indicates the presence of traumatic brain injury and a decrease of EMAP-II indicates the presence of ischemic brain injury.
    Type: Application
    Filed: October 28, 2008
    Publication date: March 12, 2009
    Inventors: Jitendra Ramanlal Dave, Changping Yao, Anthony Joseph Williams, Xi-Chun May, Frank Casper Tortella, Ka-Wang Kevin Wang, Ronald Lawrence Hayes