Abstract: Methods and systems for segmenting sequencing regions obtained from a sample interval are disclosed. sample contamination detection are disclosed. In particular, an analytics system accesses test sequences from a sample. The test sequences each include a sequencing region which, in aggregate, form an aggregate sequencing region. The analytics system segments sequencing regions from the aggregate sequencing region into sequencing subregions. Several methods of segmenting sequencing regions into sequencing subregions are disclosed: (1) maximizing cancer vs. non-cancer methylation beta differences, (2) minimizing cancer vs. non-cancer methylation beta differences, (3) segmentation based on CpG density in regions, (4) dynamic generation of sequencing subregions based on mutual information scores and cancer classification propensity. The analytics system applies selects sequencing subregions and applies a cancer classifier to those subregions to identify cancer presence in the sample.

Abstract: Methods and systems for redacting non-indicative test sequences from test samples including both indicative and non-indicative test samples are disclosed. Generally, identified non-indicative test sequences originate from WBC cfDNA while indicative test sequences originate from cfDNA associated with the identification of cancer presence in a sample. To identify non-indicative test sequences, the system applies a disambiguation model to test sequences in a test sample. The disambiguation model matches genomic regions from test sequences in a test sample to those in test sequences from a sample cohort. The model then generates a feature set for the matched test sequences and determines a probability that sequences from the test sample represent cfDNA from WBCs. In representing cfDNA from WBCs, the system redacts those test sequences from the sample to form a classification population and applies a cancer classifier to the classification population.

Abstract: Methods and systems for segmenting sequencing regions obtained from a sample interval are disclosed. sample contamination detection are disclosed. In particular, an analytics system accesses test sequences from a sample. The test sequences each include a sequencing region which, in aggregate, form an aggregate sequencing region. The analytics system segments sequencing regions from the aggregate sequencing region into sequencing subregions. Several methods of segmenting sequencing regions into sequencing subregions are disclosed: (1) maximizing cancer vs. non-cancer methylation beta differences, (2) minimizing cancer vs. non-cancer methylation beta differences, (3) segmentation based on CpG density in regions, (4) dynamic generation of sequencing subregions based on mutual information scores and cancer classification propensity. The analytics system applies selects sequencing subregions and applies a cancer classifier to those subregions to identify cancer presence in the sample.

Abstract: One or more techniques for optimizing cancer classification based on covariate characteristics is disclosed. In a first approach, an analytics system may determine separate cutoff thresholds for positively detecting disease signal for different labels for a covariate characteristic. The system may subdivide training samples based on their labels for the covariate characteristic, to separately determine the cutoff thresholds. In other approaches, the system may train disparate classifiers for each population. The system separates the training samples based on their labels for the covariate characteristic, and separately trains classifiers to generate a signal vector representing an amount of disease signal detected in a sample. The classifiers may be trained on different feature sets as determined based on mutual information gain, genomic region coverage, and healthy activation fraction.

Abstract: A system and methods comprise a gateway that includes a processor coupled to a security system at a premises. A touchscreen at the premises is coupled to the gateway and presents user interfaces. The user interfaces include a security interface that provides control of functions of the security system and access to data collected by the security system, and a network interface that provides access to network devices. A camera is located at the premises and coupled to the gateway via a plurality of interfaces. A security server at a remote location is coupled to the gateway. The security server comprises a client interface through which remote client devices exchange data with the gateway and the security system.

Abstract: A system and methods comprise a gateway that includes a processor coupled to a security system at a premises. A touchscreen at the premises is coupled to the gateway and presents user interfaces. The user interfaces include a security interface that provides control of functions of the security system and access to data collected by the security system, and a network interface that provides access to network devices. A camera is located at the premises and coupled to the gateway via a plurality of interfaces. A security server at a remote location is coupled to the gateway. The security server comprises a client interface through which remote client devices exchange data with the gateway and the security system.

Abstract: Methods and systems for segmenting sequencing regions obtained from a sample interval are disclosed. sample contamination detection are disclosed. In particular, an analytics system accesses test sequences from a sample. The test sequences each include a sequencing region which, in aggregate, form an aggregate sequencing region. The analytics system segments sequencing regions from the aggregate sequencing region into sequencing subregions. Several methods of segmenting sequencing regions into sequencing subregions are disclosed: (1) maximizing cancer vs. non-cancer methylation beta differences, (2) minimizing cancer vs. non-cancer methylation beta differences, (3) segmentation based on CpG density in regions, (4) dynamic generation of sequencing subregions based on mutual information scores and cancer classification propensity. The analytics system applies selects sequencing subregions and applies a cancer classifier to those subregions to identify cancer presence in the sample.

Abstract: A system and methods comprise a touchscreen at a premises. The touchscreen includes a processor coupled to a security system at the premises. User interfaces are presented via the touchscreen. The user interfaces include a security interface that provides control of functions of the security system and access to data collected by the security system, and a network interface that provides access to network devices. A camera at the premises is coupled to the touchscreen via a plurality of interfaces. A security server at a remote location is coupled to the touchscreen. The security server comprises a client interface through which remote client devices exchange data with the touchscreen and the security system.

Abstract: A system and methods comprise a gateway that includes a processor coupled to a security system at a premises. A touchscreen at the premises is coupled to the gateway and presents user interfaces. The user interfaces include a security interface that provides control of functions of the security system and access to data collected by the security system, and a network interface that provides access to network devices. A camera is located at the premises and coupled to the gateway via a plurality of interfaces. A security server at a remote location is coupled to the gateway.

Abstract: A system and methods comprise a gateway that includes a processor coupled to a security system at a premises. A touchscreen at the premises is coupled to the gateway and presents user interfaces. The user interfaces include a security interface that provides control of functions of the security system and access to data collected by the security system, and a network interface that provides access to network devices. A camera is located at the premises and coupled to the gateway via a plurality of interfaces. A security server at a remote location is coupled to the gateway. The security server comprises a client interface through which remote client devices exchange data with the gateway and the security system.

Abstract: A system and methods comprise a touchscreen at a premises. The touchscreen includes a processor coupled to a security system at the premises. User interfaces are presented via the touchscreen. The user interfaces include a security interface that provides control of functions of the security system and access to data collected by the security system, and a network interface that provides access to network devices. A camera at the premises is coupled to the touchscreen via a plurality of interfaces. A security server at a remote location is coupled to the touchscreen. The security server comprises a client interface through which remote client devices exchange data with the touchscreen and the security system.

Abstract: A system and methods comprise a touchscreen at a premises. The touchscreen includes a processor coupled to a security system at the premises. User interfaces are presented via the touchscreen. The user interfaces include a security interface that provides control of functions of the security system and access to data collected by the security system, and a network interface that provides access to network devices. A camera at the premises is coupled to the touchscreen via a plurality of interfaces. A security server at a remote location is coupled to the touchscreen. The security server comprises a client interface through which remote client devices exchange data with the touchscreen and the security system.

Abstract: A system and methods comprise a gateway that includes a processor coupled to a security system at a premises. A touchscreen at the premises is coupled to the gateway and presents user interfaces. The user interfaces include a security interface that provides control of functions of the security system and access to data collected by the security system, and a network interface that provides access to network devices. A camera is located at the premises and coupled to the gateway via a plurality of interfaces. A security server at a remote location is coupled to the gateway.

Abstract: Methods and systems for communication of premises data are disclosed. An example system may comprise a computing device configured to receive premises data from a plurality of devices located at a premises. The plurality of devices may be associated with different systems. Each system may comprise a different server, protocol, or device type. The computing device may coordinate communication between the plurality of devices and corresponding servers. The computing device may also send, based on data from a device associated with one system, a control message to a device associated with another system.

Abstract: A system and methods comprise a gateway that includes a processor coupled to a security system at a premises. A touchscreen at the premises is coupled to the gateway and presents user interfaces. The user interfaces include a security interface that provides control of functions of the security system and access to data collected by the security system, and a network interface that provides access to network devices. A camera is located at the premises and coupled to the gateway via a plurality of interfaces. A security server at a remote location is coupled to the gateway. The security server comprises a client interface through which remote client devices exchange data with the gateway and the security system.

Abstract: A system and methods comprise a touchscreen at a premises. The touchscreen includes a processor coupled to a security system at the premises. User interfaces are presented via the touchscreen. The user interfaces include a security interface that provides control of functions of the security system and access to data collected by the security system, and a network interface that provides access to network devices. A camera at the premises is coupled to the touchscreen via a plurality of interfaces. A security server at a remote location is coupled to the touchscreen. The security server comprises a client interface through which remote client devices exchange data with the touchscreen and the security system.

Abstract: A system comprises a bridge server configured to exchange event data and control data with premises devices. An application server coupled to the bridge server is configured to exchange the event data and the control data with the bridge server. The application server includes virtual devices comprising logical models corresponding to the premises devices and configured to use the event data and the control data to maintain state of the premises devices. The application server includes a rules engine configured to control interaction among the premises devices. An application engine coupled to the application server communicates with a device application configured for execution when installed on a remote device. The device application generates a user interface configured to present the event data and state of the premises devices and receive as input the control data of the premises devices.

Abstract: A system and methods for performing authentication to enable a user to access a site monitoring system are provided. The authentication includes voice authentication having at least one threshold that may be dynamically adjustable between false-rejection and false-acceptance. The system includes a processor configured to adjust the at least one threshold for the voice authentication based on at least one factor associated with the site monitoring system. The processor may be configured to perform voice authentication based on the adjusted at least one threshold to authenticate the user.

Abstract: The present disclosure relates to methods, apparatuses, systems, and computer program products for processing commands for accessing solid state drives. Example methods can include receiving, from a host, a loaded command availability message. The loaded command availability message can indicate that a command associated with the loaded command availability message uses a low latency mode. The methods can further include executing the associated command.