Abstract: Systems and methods for coating surgical needles are provided.

Abstract: Systems and methods for coating surgical needles are provided.

Abstract: Systems and methods for coating surgical needles are provided.

Abstract: This disclosure describes an adaptive NK cell, an isolated population of adaptive Natural Killer (NK) cells, a composition including an adaptive NK cell, and methods for producing, preparing, and using an adaptive NK cell or an isolated population or composition including an adaptive NK cell. The adaptive NK cells may be used to treat a viral infection or a tumor.

Abstract: This disclosure describes an adaptive NK cell, an isolated population of adaptive Natural Killer (NK) cells, a composition including an adaptive NK cell, and methods for producing, preparing, and using an adaptive NK cell or an isolated population or composition including an adaptive NK cell. The adaptive NK cells may be used to treat a viral infection or a tumor.

Abstract: Systems and methods for coating surgical needles are provided.

Abstract: This disclosure describes an adaptive NK cell, an isolated population of adaptive Natural Killer (NK) cells, a composition including an adaptive NK cell, and methods for producing, preparing, and using an adaptive NK cell or an isolated population or composition including an adaptive NK cell. The adaptive NK cells may be used to treat a viral infection or a tumor.

Abstract: A novel silicone coating process for surgical needles is disclosed. Coating solutions are applied to a surgical needle and a stream of air is directed at the needle in a direction substantially parallel to the central longitudinal axis of the distal section of the needle, providing superior coatings and performance.

Abstract: A novel silicone coating process for surgical needles is disclosed. Coating solutions are applied to a surgical needle and a stream of air is directed at the needle in a direction substantially parallel to the central longitudinal axis of the distal section of the needle, providing superior coatings and performance.

Abstract: A medical device having an antimicrobial coating. The device has a first coating layer having an antimicrobial agent over at least part of the outer surfaces of the device. The first coating has an outer surface. There is a second discontinuous polymeric coating containing an antimicrobial agent, which is on top of and covering part of the outer surface of the first coating. The second discontinuous coating has a microstructure.

Abstract: Curved surgical needles made from tungsten rhenium alloys are disclosed. The curved surgical needles have body flats. The needles have improved resistance to cracking.

Abstract: A medical device having an antimicrobial coating. The device has a first coating layer having an antimicrobial agent over at least part of the outer surfaces of the device. The first coating has an outer surface. There is a second discontinuous polymeric coating containing an antimicrobial agent, which is on top of and covering part of the outer surface of the first coating. The second discontinuous coating has a microstructure.

Abstract: A fluid reservoir for a medical infusion system includes an expandable elastomeric bladder defining a chamber for receiving and containing a volume of therapeutic substance and exerting pressure thereon to dispense the therapeutic substance from the bladder. The bladder has preferably a single port formed through the thickness thereof. A bi-directional valve is in fluid communication with the chamber of the elastomeric bladder and is used for filling the bladder chamber with the therapeutic substance and for connecting to a catheter assembly for dispensing the therapeutic substance to a patient undergoing treatment. The single port of the elastomeric bladder is connected to a medical grade flexible tubing, which is also connected to the bi-directional valve.

Abstract: A medical device includes a medical device flexible conduit that has an elongated Nitinol strip with a distal end, a proximal end, a longitudinal axis running from the distal end to the proximal end, a sharp head extending from the distal end, and a channel etched therein. Moreover, the channel is dispositioned along the longitudinal axis. The medical device flexible conduit also has a flexible tube at least partially jacketing the elongated Nitinol strip between the distal end and the proximal end, with the channel and the flexible tube defining a conduit. The medical device also includes an insertion mechanism configured to insert a portion of the flexible conduit, including the sharp head, into a user's target site such that the conduit provides fluid communication to the target site.

Abstract: A method for inserting a medical device flexible conduit into a user's target site includes adhering a medical device to a user with the medical device including a medical device flexible conduit and an insertion mechanism. Moreover, the medical device flexible conduit has an elongated Nitinol strip with a distal end, a proximal end, a longitudinal axis running from the distal end to the proximal end, a sharp head extending from the distal end, and a channel etched therein. In addition, the channel is dispositioned along the longitudinal axis. The medical device flexible conduit also includes a flexible tube at least partially jacketing the elongated Nitinol strip between the distal end and the proximal end, the channel and flexible tube defining a conduit. The insertion mechanism is configured to insert a portion of the flexible conduit including the sharp head into a user's target site such that the conduit provides fluid communication to the target site.

Abstract: A medical device flexible conduit includes an elongated Nitinol strip with a distal end, a proximal end, a longitudinal axis running from the distal end to the proximal end, a sharp head extending from the distal end, and a channel etched therein. Moreover, the channel is dispositioned along the longitudinal axis. The medical device flexible conduit also includes a flexible tube at least partially jacketing the elongated Nitinol strip between the distal end and the proximal end with the channel and the flexible tube defining a conduit. A method for manufacturing a medical device flexible conduit includes etching a channel into an elongated Nitinol strip and forming a sharp head on a distal end of the elongated Nitinol strip. The method also includes subsequently jacketing the flat elongated Nitinol strip with a flexible tube such that the flexible tube and channel define a conduit.

Abstract: A composite part made from a sheet molding compound is disclosed as having improved characteristics over traditional sheet molding compound composite parts. The fibrous material is introduced as a veil layer adjacent a paste layer, the veil flows well during the molding process. The improved flow and surface characteristics of a composite part are attributed to the elongation of the veil during molding and to the improved filling capabilities.

Abstract: A fluid reservoir for a medical infusion system includes an expandable elastomeric bladder defining a chamber for receiving and containing a volume of therapeutic substance and exerting pressure thereon to dispense the therapeutic substance from the bladder. The bladder has preferably a single port formed through the thickness thereof. A bi-directional valve is in fluid communication with the chamber of the elastomeric bladder and is used for filling the bladder chamber with the therapeutic substance and for connecting to a catheter assembly for dispensing the therapeutic substance to a patient undergoing treatment. The single port of the elastomeric bladder is connected to a medical grade flexible tubing, which is also connected to the bi-directional valve.

Abstract: The metal-injection molding (MIM) process offers distinct advantages over conventional wire-based methods for producing suture needles. Methods for producing unique suture receiving holes that accommodate large diameter sutures and facilitate adhesive attachment of said sutures are described herein. Additionally, methods for producing cutting edge suture needles that exhibit exemplary tissue penetration performance are described. Finally, the ductility of suture needles produced via the MIM process have been enhanced substantially by employing processes that reduce the internal porosity of the suture needle component.

Abstract: Methods and devices are disclosed for the in-vivo creation and maintenance of contiguous fluid passages in tissue through the use of tissue buttressing portions with interrupted perimeter walls. These portions can be formed from hollow fiber or extruded components. One end of the tissue-buttressing portion is connected to a hollow tube, which may be connected to a fluid source. The other end of the buttressing portion may be attached to a needle or other device suitable for the penetration of tissue and the formation of passageways in tissue. When the device is installed in tissue, the hollow tube portion of the device is passed part way through the surface of the patient and serves as the conduit for the transfer of fluid to the implanted tissue-buttressing portion of the device. The presence of the buttressing portion within the tissue causes a bridging of the local tissue thereby forming an infusion passage between the external surface of the buttressing portion and the abutting tissue.