Patents by Inventor Frank Davis

Frank Davis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230364037
    Abstract: The present invention provides novel drug combinations, pharmaceutical compositions, as well as methods involving novel therapeutic regimes for targeting cancer stem cells, as well as methods of use thereof, for the treatment and management of cancerous and non-cancerous tumours in a patient. In particular, the present invention provides novel drug combinations and pharmaceutical compositions that target components of the Renin Angiotensin System shown to expressed by cancer stem cells.
    Type: Application
    Filed: May 22, 2023
    Publication date: November 16, 2023
    Inventors: Paul Frank Davis, Tinte Itinteang, Reginald Walter Marsh, Swee Thong Tan
  • Publication number: 20230090708
    Abstract: The present invention relates to methods and compositions for the treatment of hemangioma, and particularly, but not exclusively, methods and compositions for the treatment of infantile hemangioma. In certain aspects, the methods comprise locally administering an ACE inhibitor or an ATIIR2 antagonist to a subject. In other aspects, the methods comprise systemically administering two or more of an ACE inhibitor, a beta-blocker and an ATIIR2 antagonist. The present invention also relates to compositions that are suitable for local administration and comprise: an ACEi and a beta-blocker; an ACEi and an ATIIR2 antagonist; a beta-blocker and an AT11R2 antagonist; or, an ACEi, a beta-blocker, and an AT11R2 antagonist.
    Type: Application
    Filed: January 29, 2021
    Publication date: March 23, 2023
    Inventors: Paul Frank DAVIS, Sean Marshall MACKAY, Erin Fay PATERSON, Swee Thong TAN, Eng Wui TAN
  • Publication number: 20200197335
    Abstract: The present invention provides novel drug combinations, pharmaceutical compositions, as well as methods involving novel therapeutic regimes for targeting cancer stem cells, as well as methods of use thereof, for the treatment and management of cancerous and non-cancerous tumours in a patient. In particular, the present invention provides novel drug combinations and pharmaceutical compositions that target components of the Renin Angiotensin System shown to expressed by cancer stem cells.
    Type: Application
    Filed: January 31, 2018
    Publication date: June 25, 2020
    Inventors: Paul Frank Davis, Tinte Itinteang, Reginald Walter Marsh, Swee Thong Tan
  • Publication number: 20200041521
    Abstract: The present invention provides a novel approach to cancer diagnosis and therapy of cancer by providing compositions and methods for the identification and specific targeting of the cancer stem cell populations present in a tumour to eradicate, or slow or prevent tumour (5) growth and spread, including the potential for tumour metastasis, by modulation of the Renin-Angiotensin System including, but not limited to, Renin Receptor, Angiotensin II Receptor (2) and a secreted form of the Renin Receptor.
    Type: Application
    Filed: March 4, 2019
    Publication date: February 6, 2020
    Inventors: Ranui Francesca Baillie, Paul Frank Davis, Tinte Itinteang, Swee Thong Tan
  • Patent number: 10281472
    Abstract: The present invention provides a novel approach to cancer diagnosis and therapy of cancer by providing compositions and methods for the identification and specific targeting of the cancer stem cell populations present in a tumor to eradicate, or slow or prevent tumor (5) growth and spread, including the potential for tumor metastasis, by modulation of the Renin-Angiotensin System including, but not limited to, Renin Receptor, Angiotensin II Receptor (2) and a secreted form of the Renin Receptor.
    Type: Grant
    Filed: August 12, 2015
    Date of Patent: May 7, 2019
    Assignee: GILLIES MCINDOE RESEARCH INSTITUTE
    Inventors: Ranui Francesca Baillie, Paul Frank Davis, Tinte Itinteang, Swee Thong Tan
  • Publication number: 20190048416
    Abstract: The present invention provides a novel approach to the diagnosis, treatment and management of a fibrotic lesion by providing compositions and methods for the identification and specific targeting of the embryonic stem cell populations known to be associated with a fibrotic lesion, by modulation of the Renin-Angiotensin System.
    Type: Application
    Filed: November 30, 2016
    Publication date: February 14, 2019
    Inventors: Swee Thong Tan, Paul Frank Davis, Tinte Itinteang
  • Publication number: 20170360829
    Abstract: The present invention provides a novel approach to the diagnosis, treatment and management of vascular anomalies by providing compositions and methods for the identification and specific targeting of the embryonic stem cell populations associated with vascular anomalies, by modulation of the Renin-Angiotensin System expressed by the stem cells.
    Type: Application
    Filed: February 27, 2017
    Publication date: December 21, 2017
    Inventors: Swee Thong Tan, Paul Frank Davis, Tinte Itinteang
  • Publication number: 20170234884
    Abstract: The present invention provides a novel approach to cancer diagnosis and therapy of cancer by providing compositions and methods for the identification and specific targeting of the cancer stem cell populations present in a tumour to eradicate, or slow or prevent tumour (5) growth and spread, including the potential for tumour metastasis, by modulation of the Renin-Angiotensin System including, but not limited to, Renin Receptor, Angiotensin II Receptor (2) and a secreted form of the Renin Receptor.
    Type: Application
    Filed: August 12, 2015
    Publication date: August 17, 2017
    Inventors: Ranui Francesca BAILLIE, Paul Frank DAVIS, Tinte ITINTEANG, Swee Thong TAN
  • Publication number: 20150174079
    Abstract: A solid lozenge composition for oral dissolution. The solid lozenge composition includes an inactive carrier medium that is a solid at room temperature, at least one flavoring component, and silver nanoparticles. The concentration of silver nanoparticles is between about 0.1 micrograms per teaspoon and 5 micrograms per teaspoon.
    Type: Application
    Filed: December 24, 2014
    Publication date: June 25, 2015
    Inventors: Frank Davis, Andrew Atkinson, Elaine Atkinson
  • Publication number: 20130319890
    Abstract: A disposable personal hygiene article includes a container, a bag inside the container, and a release mechanism. The container is attached to a personal hygiene article portion. During disposal, the bag is released from the container via the release mechanism and is configured to fit the personal hygiene article for disposal.
    Type: Application
    Filed: June 5, 2013
    Publication date: December 5, 2013
    Inventors: Frank Davis, Iwona Davis
  • Publication number: 20120077281
    Abstract: The invention relates to a device for estimating total antioxidant capacity (TAC) of a range of fluids and extracts. More particularly the invention relates to a device where the TAC is measured using lateral flow technology on a solid support. For example, the device may be a test strip.
    Type: Application
    Filed: September 22, 2011
    Publication date: March 29, 2012
    Inventors: John Harley Loveless BEAL, Paul Frank DAVIS
  • Patent number: 8135605
    Abstract: A tool to assess risks associated with software applications, and controls implemented to mitigate these risks, includes a first software component configured to gather information about the risks and controls, and a second software component configured to display the gathered information. The first software component includes a self-assessment tool which is invoked by a user to enter information reflective of risk levels over a number of risk categories. These risk levels are used to calculate a risk score associated with a particular application. The user also enters information as to whether or not a number of specific control attributes have been implemented, and this information is used to calculate a control score.
    Type: Grant
    Filed: April 11, 2006
    Date of Patent: March 13, 2012
    Assignee: Bank of America Corporation
    Inventors: Frank Davis Osborn, Jacob Firestone, David H. Weaver, Peter Murphy
  • Publication number: 20080193549
    Abstract: Oil obtained from the liver of hoki fish is a potent inhibitor of angiogenesis and inflammation, and a modulator of the immune system. Compositions containing hoki liver oil, or fractions thereof, are useful for treating diseases or disorders associated with angiogenesis and inflammation. Certain oil fractions are potent stimulants of the immune system whereas other fractions are potent suppressants of the immune system.
    Type: Application
    Filed: July 5, 2005
    Publication date: August 14, 2008
    Applicant: Otago Innovation Limited
    Inventor: Paul Frank Davis
  • Patent number: 7378180
    Abstract: A battery includes an air electrode and an air access passageway that is closed by a non-liquid valve actuable by differential pressure to provide an opening therein to admit air to the battery.
    Type: Grant
    Filed: September 4, 2003
    Date of Patent: May 27, 2008
    Assignee: The Gillette Company
    Inventors: Brian Edward Causton, Frank Davis, Neville Keith Lacey, Larry Liaobo Yu
  • Publication number: 20070295316
    Abstract: Methods and apparatus are disclosed for operation of a multiple fuel engine, which runs on a combination of two or more fuels. An electronic control unit (ECU) may be connected to the existing components of an engine system in order to control operation of the multiple fuel engine. The engine system may be mechanically governed or electronically controlled. The ECU inputs operating characteristics of the engine system, determines governing characteristics for multiple fuel operation based on the operating characteristics, and controls the amounts of fuel delivered to the engine based on the governing characteristics. In a preferred embodiment, a dual fuel engine operates using diesel as a first fuel and natural gas as a second fuel. The operating characteristics may include engine speed, throttle position, engine exhaust temperature, gas pressure of the second fuel, gas temperature of the second fuel, boost pressure of an intake manifold, or engine coolant temperature.
    Type: Application
    Filed: May 21, 2007
    Publication date: December 27, 2007
    Inventors: Frank Davis, Jozef Turlej
  • Publication number: 20050155315
    Abstract: A strengthened, inexpensive roof-to-wall bracket that includes two perpendicularly aligned wall flange members, integrally formed on a wall transverse member, and two perpendicularly aligned rafter flange members integrally formed on the wall transverse member. Disposed under the corners between the two wall flange members and the wall transverse member is and L-shaped secondary angle member. In the preferred embodiment, the L-shaped angle member formed by cutting a square or rectangular cutout in the adjoining wall flange member and then bending the waste material upward to form the angle member. The angle member is disposed along the corners and along the adjoining inside surfaces of the wall flange member and the wall transverse member. Optional welds may be used to physically connect the angle member to the inside surfaces of the wall flange and wall transverse member. Optional gussets may be formed on the corners between the wall flange surface and the wall transverse member for added strength.
    Type: Application
    Filed: January 14, 2005
    Publication date: July 21, 2005
    Inventors: Frank Davis, Ed Rouser
  • Publication number: 20040048145
    Abstract: A battery includes an air electrode and an air access passageway that is closed by a non-liquid valve actuable by differential pressure to provide an opening therein to admit air to the battery.
    Type: Application
    Filed: September 4, 2003
    Publication date: March 11, 2004
    Inventors: Brian Edward Causton, Frank Davis, Neville Keith Lacey, Larry Liaobo Yu
  • Publication number: 20040009233
    Abstract: An extract obtained from shark meat, which extract is capable of inhibiting angiogenesis in an animal. A process for obtaining the extract by contacting shark meat with a solvent, separating the resulting solution from the meat, then removing the solvent to give an extract which is an inhibitor of angiogenesis. The use of the extract for treatment of diseases associated with angiogenesis including cancer, retinopathy, inflammation, and arthritis.
    Type: Application
    Filed: July 25, 2003
    Publication date: January 15, 2004
    Inventors: Paul Frank Davis, Andrew Douglas Mackenzie
  • Patent number: 6599134
    Abstract: A low profile, 1U expansion PC board for mounting at least two PCI connectors, mountable by a male-to-male connector to a PCI matrix on the transverse side of a 1U PICMG computer backplane. Additional mechanical security is provided by mounting stanchions between the board and the backplane.
    Type: Grant
    Filed: June 4, 2001
    Date of Patent: July 29, 2003
    Inventors: Frank Duarte, Frank Davis
  • Patent number: 6486982
    Abstract: A system for converting an image into a hologram formed from diffraction gratings includes obtaining image data for each pixel in an image to be converted, putting it into digital form and using the image data to control portions of a laser beam split into a reference beam and at least one object beam. The diffraction gratings are formed by an interference pattern of a reference beam and at least one object beam intersecting on the surface of a photoresist material on a pixel-by-pixel basis. Modulation of at least one object beam and adjustment of the angle at which that beam interferes with the reference beam on the photoresist material is used to reflect image data for each pixel of the image being converted into a hologram consisting of diffraction gratings.
    Type: Grant
    Filed: October 8, 1998
    Date of Patent: November 26, 2002
    Assignee: Illinois Tool Works Inc.
    Inventor: Frank Davis