Patents by Inventor Frank DeLustro

Frank DeLustro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dehydrated collagen-polymer strings
    Patent number: 5308889
    Abstract: Medical articles in the form of strings are formed by covalently binding collagen to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide collagen/polymer conjugate formulations which are extruded to make the strings. The collagen may be recombinantly produced human collagen or collagen extracted from any source, such as a bovine source or human placenta, and purified and can be of various types and may be fibrillar or non-fibrillar. The synthetic hydrophilic polymer may be polyethylene glycol and derivatives thereof having an average molecular weight over a range of from about 100 to about 20,000. The string can be designed to incorporate other components such as fluid, pharmaceutically acceptable carriers to form injectable formulations, and/or biologically active proteins such as growth factors or cytokines. The strings contain large amounts of water when extruded and may then be dehydrated to form relatively solid but flexible strings.
    Type: Grant
    Filed: December 2, 1992
    Date of Patent: May 3, 1994
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Louis Fries, Ramesh Damani, Kimberly McCullough, Frank DeLustro
  • Method of augmenting tissue with collagen-polymer conjugates
    Patent number: 5306500
    Abstract: Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.
    Type: Grant
    Filed: August 23, 1993
    Date of Patent: April 26, 1994
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Collagen-polymer conjugates
    Patent number: 5304595
    Abstract: Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.
    Type: Grant
    Filed: December 30, 1992
    Date of Patent: April 19, 1994
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Composition for bone repair
    Patent number: 5264214
    Abstract: Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.
    Type: Grant
    Filed: August 14, 1992
    Date of Patent: November 23, 1993
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Collagen-polymer conjugates
    Patent number: 5162430
    Abstract: Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.
    Type: Grant
    Filed: November 14, 1989
    Date of Patent: November 10, 1992
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz