Abstract: A platform for cultivation, maintenance, and/or analysis of one or more bio-objects includes one or more integrated bio-object microfluidics modules. Each integrated bio-object microfluidics module is configured to cultivate, maintain, analyze and/or mimic functionalities of a respective bio-object, and includes one or more on-chip pumps; a plurality of fluidic switches; and a microfluidic chip in fluid communication with the one or more on-chip pumps and the plurality of fluidic switches, having at least one chamber for accommodating the bio-object and a plurality of fluidic paths connecting the at least one chamber, the one or more on-chip pumps and the plurality of fluidic switches, and a power and control unit adapted for selectively and individually controlling the one or more on-chip pumps and the plurality of fluidic switches for performing bio-object microfluidics functions.

Abstract: A detector for determining the volume and volumetric changes of respiratory gases in a closed circuit anaesthesia circuit having a bellows ventilator. The device includes a first sensor positioned with respect to the bellows for detecting and indicating when the bellows assumes a given expanded position in a bellows housing indicative of the given volume of respiratory gas in the circuit. A second sensor detects and indicates when the bellows assumes an expanded position indicative of the greater amount of expansion than that corresponding to the given expanded position. During respiratory cycles of the patient, indications from the first sensor in the absence of indications from the second sensor indicates that the volume of gas in the closed circuit anaesthesia circuit is not changing, but is remaining at that corresponding to the given expanded position of the bellows.