Abstract: A method of stimulating and controlling stem cell activity and differentiation on a modified material substrate and a device including the modified material substrate are provided. The method includes providing a material substrate configured for medical use. The material substrate includes at least one surface or interior area available for modification, and the at least one surface or interior area is treated with a plurality of pulsed light beams to obtain a modified material substrate with at least one modified surface or interior area. The at least one modified surface or interior area has a biomimetic architecture with surface and bulk (interior) features, properties, and textures configured to accelerate and control stem cell differentiation when the modified material substrate is contacted with stem cells.

Abstract: A method of stimulating and controlling stem cell activity and differentiation on a modified material substrate and a device including the modified material substrate are provided. The method includes providing a material substrate configured for medical use. The material substrate includes at least one surface or interior area available for modification, and the at least one surface or interior area is treated with a plurality of pulsed light beams to obtain a modified material substrate with at least one modified surface or interior area. The at least one modified surface or interior area has a biomimetic architecture with surface and bulk (interior) features, properties, and textures configured to accelerate and control stem cell differentiation when the modified material substrate is contacted with stem cells.

Abstract: A method of encoding information on a material substrate and a device including the modified material substrate are provided. The method includes providing a material substrate having at least one exposed surface or interior (bulk) location with an initial material state, treating the exposed surface or interior location with an energy source, wherein the energy source encodes encryption information on the exposed surface or interior location to provide a modified material substrate having an exposed surface or interior location with an intermediate material state, and then treating the exposed surface or interior location with an intermediate material state with the energy source to encode decipher information on the exposed surface or interior location to provide a remodified material substrate having an exposed surface or interior location with a final material state.

Abstract: A multi-layer substrate apparatus includes a first layer configured to provide at least one electrical-based property. A second layer proximate to the first layer is configured to provide at least one mechanical-based property. A third proximate to the second layer includes at least one chemical component such that the third layer is enabled to regulate the multi-layer substrate apparatus based on a system that the multi-layer substrate apparatus is being used with. A fourth layer proximate to the third layer is configured to provide at least one magnetic-based property. A fifth layer proximate to the fourth layer is configured to provide support based on the system that the multi-layer substrate apparatus is being used with. The fifth layer includes a geometric portion that is configured to facilitate at least one process therein.

Abstract: A system includes a computing device that generates at least one process script for the modification to a glass ceramic substrate and at least one pattern script that corresponds to the process script. The computing device also merges the process script with the pattern script and generates a plurality of command signals that are based on the merged process and pattern scripts. An energy source generates a plurality of light beams based on the generated command signal(s). A waveform apparatus generates at least one waveform signal to customize the generated light beams based on the generated command signal(s). At least one modulating component modulates the generated light beams based on generated command signal(s). An optical assembly is configured to apply the modulated plurality of light beams to the glass ceramic substrate.

Abstract: A multi-layer substrate apparatus includes a first layer configured to provide at least one electrical-based property. A second layer proximate to the first layer is configured to provide at least one mechanical-based property. A third proximate to the second layer includes at least one chemical component such that the third layer is enabled to regulate the multi-layer substrate apparatus based on a system that the multi-layer substrate apparatus is being used with. A fourth layer proximate to the third layer is configured to provide at least one magnetic-based property. A fifth layer proximate to the fourth layer is configured to provide support based on the system that the multi-layer substrate apparatus is being used with. The fifth layer includes a geometric portion that is configured to facilitate at least one process therein.

Abstract: A system includes a computing device that generates at least one process script for the modification to a material substrate and at least one pattern script that corresponds to the process script. The computing device also merges the process script with the pattern script and generates a plurality of command signals that are based on the merged process and pattern scripts. An energy source generates a plurality of light beams based on the generated command signal(s). At least one modulating component modulates the generated light beams based on generated command signal(s). A waveform apparatus generates at least one waveform signal to customize the generated light beams based on the generated command signal(s). A motion control apparatus controls at least one parameter of the light beams based on the generated command signal(s).

Abstract: A material modification assembly comprises an energy source for generating light beams to modify a substrate. A computing device generates pattern script(s) based on at least one parameter of the modification. The computing device also generates process script(s) including a type of pulse scripts to be used with the light beams and are based on at least one parameter of the interaction between the energy source and the substrate. The computing device combines the pattern script(s) with the process script(s) and generates command signals based on the combination. The computing device transmits the command signals to one or more additional devices of the material modification assembly to facilitate modifying the light beams for the modification to the substrate such that the modification includes a pattern on at least a surface of the substrate having dimensions and includes two or more discrete material alterations or changes spatially overlapped within the pattern.

Abstract: A system includes a computing device that generates at least one process script for the modification to a glass ceramic substrate and at least one pattern script that corresponds to the process script. The computing device also merges the process script with the pattern script and generates a plurality of command signals that are based on the merged process and pattern scripts. An energy source generates a plurality of light beams based on the generated command signal(s). A waveform apparatus generates at least one waveform signal to customize the generated light beams based on the generated command signal(s). At least one modulating component modulates the generated light beams based on generated command signal(s). An optical assembly is configured to apply the modulated plurality of light beams to the glass ceramic substrate.

Abstract: A system includes a computing device that generates at least one process script for the modification to a material substrate and at least one pattern script that corresponds to the process script. The computing device also merges the process script with the pattern script and generates a plurality of command signals that are based on the merged process and pattern scripts. An energy source generates a plurality of light beams based on the generated command signal(s). At least one modulating component modulates the generated light beams based on generated command signal(s). A waveform apparatus generates at least one waveform signal to customize the generated light beams based on the generated command signal(s). A motion control apparatus controls at least one parameter of the light beams based on the generated command signal(s).

Abstract: A material modification assembly comprises an energy source for generating light beams to modify a substrate. A computing device generates pattern script(s) based on at least one parameter of the modification. The computing device also generates process script(s) including a type of pulse scripts to be used with the light beams and are based on at least one parameter of the interaction between the energy source and the substrate. The computing device combines the pattern script(s) with the process script(s) and generates command signals based on the combination. The computing device transmits the command signals to one or more additional devices of the material modification assembly to facilitate modifying the light beams for the modification to the substrate such that the modification includes a pattern on at least a surface of the substrate having dimensions and includes two or more discrete material alterations or changes spatially overlapped within the pattern.

Abstract: An implant device having a non-conductive base structure with at least two exposed or exterior surfaces wherein at least one of the exposed or exterior surfaces has attained electrical conductivity on at least portions of the surface by an energy exposure wherein portions of the exposed or exterior surfaces are transformed by the energy exposure to attain the electrical conductivity.

Abstract: A pulse modulation laser writing system generates a motion control file for controlled motion of a sample under modulated laser beam exposure and generates a laser script file for generating a sequence of laser writing processes, such as, ablation, welding, texturing, and dosing, the sample while under motion control. The system enables laser writing processing of complex multimaterial samples in a single manufacturing process.