Abstract: Methods for the image processing od cells are disclosed for the purpose of segmenting cell colonies for further processing to determine confluence, counting and morphology.

Abstract: Methods for the image processing of cells are disclosed for the purpose of segmenting cell colonies for further processing to determine confluence, counting and morphology.

Abstract: Method and apparatus for displaying cultured cell wherein the image can be smoothly moved into and out of focus and can be zoomed in and out and panned.

Abstract: A plaque detection method and apparatus wherein at least one processor is programmed to receive above focus images to detect the presence of live cells without detecting the lysed cell materials, receive below focus images wherein virtual dark regions exist which are similar to cell shadows as seeds in a segmentation process and use contours around each resulting shape to obtain a subset that are more likely to be part of the cell population to define a cell map. A distance map is created in which each pixel value is the distance of that pixel from the nearest pixel of the cell map and the distance map is thresholded to create a first image of the places which are relatively far from the cells a second image with a smaller distance threshold to get an image that mimics the edges of the cells.

Abstract: A plaque detection method and apparatus wherein at least one processor is programmed to receive above focus images to detect the presence of live cells without detecting the lysed cell materials, receive below focus images wherein virtual dark regions exist which are similar to cell shadows as seeds in a segmentation process and use contours around each resulting shape to obtain a subset that are more likely to be part of the cell population to define a cell map. A distance map is created in which each pixel value is the distance of that pixel from the nearest pixel of the cell map and the distance map is thresholded to create a first image of the places which are relatively far from the cells a second image with a smaller distance threshold to get an image that mimics the edges of the cells.

Abstract: A method and apparatus for measuring cells and cell confluence includes an imager for imaging a z-stack of bright field images and a processor for selecting a best focus bright field image at a z position of f microns in the z-stack of images. In the manner described herein, the processor selects a bright image n microns lower in the z-stack than the best focus bright field image and a dark image m microns higher in the stack than the best focus bright field image. The processor applies edge detection to the dark image to obtain an edge image and subtracts the edge image from the dark image and the processor applies an adaptive threshold to the bright image to create a mask and uses the adaptive thresholded image as seeds to evaluate the edge image to find cell candidates.

Abstract: A method and system comprise taking a series of time spaced images of a cell culture having pathogens therein creating plaques, applying a stain to the cell culture, taking an image of the stained plaques, using the image of the stained culture to build a model of the plaques in earlier pre-stain images of the culture and displaying the pre-stain images and identifying the plaques therein based upon the model.

Abstract: Method and apparatus for performing a plaque detection by using above focus and below focus images. Plaque is also detected by a method and apparatus using test and training data captured on an imaging system, building a new model for a specific virus/cell/protocol type to detect plaques, using the models in runtime systems to detect plaques and augmenting the models based on automatically calculated false positive and false negative counts and percentages taken from test runs and/or runtime data.

Abstract: A plaque detection method and apparatus wherein at least one processor is programmed to receive above focus images to detect the presence of live cells without detecting the lysed cell materials, receive below focus images wherein virtual dark regions exist which are similar to cell shadows as seeds in a segmentation process and use contours around each resulting shape to obtain a subset that are more likely to be part of the cell population to define a cell map. A distance map is created in which each pixel value is the distance of that pixel from the nearest pixel of the cell map and the distance map is thresholded to create a first image of the places which are relatively far from the cells a second image with a smaller distance threshold to get an image that mimics the edges of the cells.

Abstract: Methods for the image processing od cells are disclosed for the purpose of segmenting cell colonies for further processing to determine confluence, counting and morphology.

Abstract: Method and apparatus for displaying cultured cell wherein the image can be smoothly moved into and out of focus and can be zoomed in and out and panned.

Abstract: Systems and methods for dynamic computer aided innovation via multidimensional complementary difference recommendation and exploration are disclosed including categorizing a first and second data element in a database with a first attribute and second attribute, respectively, of a first dimension, a dimension being an aspect of a situation, problem, or thing. The first and second data elements are categorized with a first attribute and a second attribute of a second dimension, the second dimension being different from the first dimension. Analyzing the first and second attribute of the first dimension and the first and second attribute of the second dimension to determine a ratio of similarity and dissimilarity; calculating a composite score of the ratio of the first dimension and the ratio of the second dimension; and generating and storing a link between the first and second data element when the composite score is within numerical limits.

Abstract: Systems and methods for dynamic computer aided innovation via multidimensional complementary difference recommendation and exploration are disclosed including categorizing a first and second data element in a database with a first attribute and second attribute, respectively, of a first dimension, a dimension being an aspect of a situation, problem, or thing. The first and second data elements are categorized with a first attribute and a second attribute of a second dimension, the second dimension being different from the first dimension. Analyzing the first and second attribute of the first dimension and the first and second attribute of the second dimension to determine a ratio of similarity and dissimilarity; calculating a composite score of the ratio of the first dimension and the ratio of the second dimension; and generating and storing a link between the first and second data element when the composite score is within numerical limits.

Abstract: Systems and methods for dynamic computer aided innovation via multidimensional complementary difference recommendation and exploration are disclosed including categorizing a first and second data element in a database with a first attribute and second attribute, respectively, of a first dimension, a dimension being an aspect of a situation, problem, or thing. The first and second data elements are categorized with a first attribute and a second attribute of a second dimension, the second dimension being different from the first dimension. Analyzing the first and second attribute of the first dimension and the first and second attribute of the second dimension to determine a ratio of similarity and dissimilarity; calculating a composite score of the ratio of the first dimension and the ratio of the second dimension; and generating and storing a link between the first and second data element when the composite score is within numerical limits.

Abstract: Systems and methods for dynamic computer aided innovation via multidimensional complementary difference recommendation and exploration are disclosed including categorizing a first and second data element in a database with a first attribute and second attribute, respectively, of a first dimension, a dimension being an aspect of a situation, problem, or thing. The first and second data elements are categorized with a first attribute and a second attribute of a second dimension, the second dimension being different from the first dimension. Analyzing the first and second attribute of the first dimension and the first and second attribute of the second dimension to determine a ratio of similarity and dissimilarity; calculating a composite score of the ratio of the first dimension and the ratio of the second dimension; and generating and storing a link between the first and second data element when the composite score is within numerical limits.

Abstract: Apparatus, systems, and methods are provided to generate markings on the surface of a die or substrate. The markings represent information. The markings can be annealed onto the surface of the die or substrate using a laser. Another embodiment can use an out-of-focus laser beam to mark a solder resist material.

Abstract: Apparatus, systems, and methods are provided to generate markings on the surface of a die or substrate. The markings represent information. The markings can be annealed onto the surface of the die or substrate using a laser. Another embodiment can use an out-of-focus laser beam to mark a solder resist material.

Abstract: A portable desk for use in the front passenger seat of a vehicle. The desk comprises of a desktop, leveling support, and securing strap. The desktop and leveling support are both generally rectangular in shape and made of a rigid, durable and lightweight material. The topside of the desktop is covered with a non-skid, heat-dissipating work surface. The top end of the leveling support is rotatively coupled perpendicularly to the underside of the desktop. The securing strap, comprising of two straps and a locking mechanism, has one end of each strap attached to each one of the two opposing sides of the leveling support.

Abstract: The present invention provides for methods and an apparatus for evaluating objects having three dimensional features. One method involves using both two dimensional data sets to improve the processing of three dimensional data sets. The two dimensional data set can be used to pre-qualify the three dimensional data set, or may be used to locate that data within the three dimensional data set that is characteristic of the three dimensional feature. The invention may include a sensor configured to capture both three dimensional and two dimensional data. The present invention provides for an efficient technique to evaluate three dimensional data. The present invention also solves heretofore unrecognized problems associated with geometric distortion.

Abstract: Methods and systems selectively irradiate structures on or within a semiconductor substrate using a plurality of pulsed laser beams. The structures are arranged in a row extending in a generally lengthwise direction. The method generates a first pulsed laser beam that propagates along a first laser beam axis that intersects the semiconductor substrate and a second pulsed laser beam that propagates along a second laser beam axis that intersects the semiconductor substrate. The method directs respective first and second pulses from the first and second pulsed laser beams onto distinct first and second structures in the row so as to complete irradiation of said structures with a single laser pulse per structure. The method moves the first and second laser beam axes relative to the semiconductor substrate substantially in unison in a direction substantially parallel to the lengthwise direction of the row, so as to selectively irradiate structures in the row with either the first or the second laser beam.