Abstract: This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.

Abstract: This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.

Abstract: Tinted ophthalmic devices, methods for their production, and non-crosslinked binding polymers used in their production are disclosed herein.

Abstract: The present invention relates to ophthalmic compositions comprising a pH between about 6 and about 8 and about 50 to about 1000 ppm hydrogen peroxide, about 100 ppm to about 2000 ppm of at least one chlorite compound and about 20 to 100 ppm of at least one saturated, polymeric quaternium salt. The ophthalmic compositions of the present invention display improved antifungal efficacy against fusarium solani.

Abstract: This invention includes methods and systems for processing silicone hydrogel ophthalmic lenses using aqueous solutions which contain dimethyl siloxane as as processing aids to facilitate lens transfer.

Abstract: The present invention relates to stabilized ophthalmic solutions comprising at least one peroxide. In one embodiment, the present invention relates to an ophthalmic solution comprising a pH between about 6 and about 8 and about 50 to about 1000 ppm hydrogen peroxide and about 0.005 wt % (50 ppm) to about 0.05 wt % (500 ppm) at least one salt of diethylenetriamine pentaacetic acid selected from the group consisting of calcium salts of diethylenetriamine pentaacetic acid, zinc salts of diethylenetriamine pentaacetic acid and mixed calcium/zinc salts of diethylenetriamine pentaacetic acid. The present invention further relates to a method for preserving ophthalmic solution comprising at least one peroxide.

Abstract: This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.

Abstract: The present invention includes methods and apparatus for forming a biomedical device, such as an ophthalmic lens, in a area defined by a first mold part and a second mold part wherein during the formation of the biomedical device a HEMA is formed and the HEMA ring and a greater adhesive force is generated on the HEMA ring by the second mold part than the first mold part.

Abstract: The present invention relates to compositions comprising a light absorbing prepolymer having a molecular weight of between about 7,000 and about 100,000 and polymeric units derived from and least one reactive light absorbing component and monomers selected from the group consisting of hydrophilic monomers, hydrophobic monomers and mixtures thereof. The compositions of the present invention are useful for the manufacture of ophthalmic devices, including contact lenses.

Abstract: The invention is the method of preparing macromer for use in making ophthalmic lenses comprising combining two or more monomers and using a macromer-forming catalyst, wherein the macromer-forming catalyst comprises triethylamine or bismuth.

Abstract: The present invention relates to compositions comprising a polymeric substrate comprising at least one volume excluding polymer. In one embodiment, the present invention provides polymeric articles that are capable of acting as osmotic drivers. The articles are capable of maintaining a desired water balance by moving water in or out of a substrate to maintain cation concentration equilibrium between the substrate and its environment.

Abstract: The present invention relates to compositions comprising poly-HEMA having a peak molecular weight between about 25,000 and about 100,000 , preferably between 25,000 and 80,000 and a polydispersity of less than about 2 to less than about 3.8 respectively and covalently bonded thereon, at least one cross-linkable functional group. The present invention further relates to low polydispersity poly-HEMA suitable for making the crosslinkable prepolymers, processes for functionalizing and purifying said poly-HEMA to form said crosslinkable prepolymers, viscous solutions made from said crosslinkable prepolymers, hydrogels made from said viscous solutions and articles made from said crosslinkable polymers, hydrogels and viscous solutions.

Abstract: This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.

Abstract: A soft contact lens containing a silicone-hydrogel made by curing a reaction mixture containing a silicone-containing monomer.

Abstract: The invention is the method of preparing macromer for use in making ophthalmic lenses comprising combining two or more monomers and using a macromer-forming catalyst, wherein the macromer-forming catalyst comprises triethylamine or bismuth.

Abstract: The present invention relates to compositions comprising poly-HEMA having a peak molecular weight between about 25,000 and about 100,000, preferably between 25,000 and 80,000 and a polydispersity of less than about 2 to less than about 3.8 respectively and covalently bonded thereon, at least one cross-linkable functional group. The present invention further relates to low polydispersity poly-HEMA suitable for making the crosslinkable prepolymers, processes for functionalizing and purifying said poly-HEMA to form said crosslinkable prepolymers, viscous solutions made from said crosslinkable prepolymers, hydrogels made from said viscous solutions and articles made from said crosslinkable polymers, hydrogels and viscous solutions.

Abstract: This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.

Abstract: A method of reducing adverse events with contact lenses by preventing microbial growth by attaching a polymer (with a molar ratio of carboxylate groups to sulfonate groups of greater than about 2) to a surface of an ophthalmic device is presented. Additionally, a method of promoting ocular health by attaching a polymer (with a molar ratio of carboxylate groups to sulfonate groups of greater than about 2) to a surface of an ophthalmic device is presented.

Abstract: A soft contact lens containing a silicone-hydrogel made by curing a reaction mixture containing a silicone-containing monomer.

Abstract: The present invention provides intra ocular lenses that have a refractive index gradient. Additionally, the lenses of the invention may be customized to correct the ocular wave front aberrations of a particular individual.