Patents by Inventor Frank Fang

Frank Fang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SCORING DEVICE AND METHODS FOR SETTING AXIAL POSITION AND GAP DIMENSION
    Publication number: 20240083063
    Abstract: A method for setting an axial position and gap dimension of a gap between one or more score blades and an anvil shaft of a rotary scoring device, includes providing a control system including a controller, at least one sensor, and at least one adjusting device actuated by the control system, and actuating the at least one adjusting device in response to the at least one sensor sensing a deviation from a desired state, thereby setting the axial position or the gap dimension between the one or more score blades and the anvil shaft. The method further includes actuating the at least one adjusting device is achieved as a result of the control system operating in a closed feedback loop, and sensing by the at least one sensor occurring with or without disruption of operation of the rotary scoring device.
    Type: Application
    Filed: September 13, 2023
    Publication date: March 14, 2024
    Inventors: Eric KOPPES, Aaron POWERS, Brady JOHNSON, Frank FANG, Casey STEVENS, Dave PURKERSON, Levi WILSON
  • MONOCLONAL ANTIBODY AGAINST HUMAN MAC-1 AND USES THEREOF
    Publication number: 20240084017
    Abstract: Monoclonal antibodies against human Mac-1 are provided. These antibodies can bind to different states of Mac-1 so as to alter the biofunctions of Mac-1. These antibodies can modulate Th1/Th2 cytokine secretions by TLR-activated immune cells and can be used for the treatments of diseases related to acute and chronic inflammatory disorders, such as infectious diseases, and cancers.
    Type: Application
    Filed: December 30, 2021
    Publication date: March 14, 2024
    Applicant: Ascendo Biotechnology, Inc.
    Inventors: Yen-Ta Lu, Chia-Ming Chang, Ping-Yen Huang, I-Fang Tsai, Frank Wen-Chi Lee
  • Compounds for the treatment of cancer
    Patent number: 11339188
    Abstract: Provided herein are compounds useful for the treatment of cancer.
    Type: Grant
    Filed: February 4, 2020
    Date of Patent: May 24, 2022
    Assignee: EISAI R&D MANAGEMENT CO., LTD.
    Inventors: Dae-Shik Kim, Frank Fang, Atsushi Endo, Hyeong-wook Choi, Ming-Hong Hao, Xingfeng Bao, Kuan-Chun Huang
  • Methods for the Treatment of Bladder Cancer
    Publication number: 20210205348
    Abstract: Provided herein are methods for the treatment of bladder cancer.
    Type: Application
    Filed: May 31, 2019
    Publication date: July 8, 2021
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Dae-Shik KIM, Frank FANG, Atsushi ENDO, Hyeong-Wook CHOI, Ming-Hong HAO, Xingfeng BAO, Kuan-Chun HUANG
  • Synthetic route to 2?-deoxy-2?,2?-difluorotetrahydrouridines
    Patent number: 11028119
    Abstract: The present invention relates to methods and intermediates for synthesizing 2?-deoxy-2?,2?-difluorotetrahydrouridine compounds.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: June 8, 2021
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Hyeong-wook Choi, Steven Mathieu, Frank Fang, Bryan Matthew Lewis
  • EP4 antagonists
    Patent number: 10941148
    Abstract: We provide compounds given by Formula I, which is shown in FIG. 3, or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: March 9, 2021
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Wanjun Zheng, Xiaojie Zhu, Hong Du, Maarten Postema, Yimin Jiang, Jing Li, Robert Yu, Hyeong-wook Choi, Jaemoon Lee, Frank Fang, Daniel Custar
  • COMPOUNDS FOR THE TREATMENT OF CANCER
    Publication number: 20200299321
    Abstract: Provided herein are compounds useful for the treatment of cancer.
    Type: Application
    Filed: February 4, 2020
    Publication date: September 24, 2020
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Dae-Shik KIM, Frank FANG, Atsushi ENDO, Hyeong-wook CHOI, Ming-Hong HAO, Xingfeng BAO, Kuan-Chun HUANG
  • Method and apparatus for suppression of spikes detected by a proximity sensor
    Patent number: 10719057
    Abstract: A method for suppressing a non-periodic random event in a proximity system includes: receiving an output signal generated by a proximity sensor in the proximity system and monitoring at least a magnitude of the output signal; determining whether a spike having a magnitude exceeding a prescribed threshold value has occurred in the output signal; when a spike in the output signal is detected, setting an output of the proximity system to a prescribed level for a prescribed duration of time; when the prescribed duration of time has elapsed, determining whether the output signal meets one or more prescribed criteria indicative of a shutdown condition; when it is determined that the output signal meets the prescribed criteria, setting the output of the proximity system to a level exceeding an alarm threshold; and when it is determined that the output signal fails to meet at least one of the prescribed criteria, releasing suppression of the output of the proximity system.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: July 21, 2020
    Assignee: METRIX INSTRUMENT CO., LP
    Inventors: Frank Fang, Everett Jesse, Matthew Webster
  • SYNTHETIC ROUTE TO 2'-DEOXY-2',2'-DIFLUOROTETRAHYDROURIDINES
    Publication number: 20200123189
    Abstract: The present invention relates to methods and intermediates for synthesizing 2?-deoxy-2?,2?-difluorotetrahydrouridine compounds.
    Type: Application
    Filed: December 17, 2019
    Publication date: April 23, 2020
    Inventors: Hyeong-wook Choi, Steven Mathieu, Frank Fang, Bryan Matthew Lewis
  • Compounds for the treatment of cancer
    Patent number: 10618930
    Abstract: Provided herein are compounds useful for the treatment of cancer.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: April 14, 2020
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Dae-Shik Kim, Frank Fang, Atsushi Endo, Hyeong-wook Choi, Ming-Hong Hao, Xingfeng Bao, Kuan-Chun Huang
  • CYCLIC DI-NUCLEOTIDES DERIVATIVE FOR THE TREATMENT OF CANCER
    Publication number: 20200055883
    Abstract: Provided herein are compounds useful for the treatment of cancer.
    Type: Application
    Filed: February 16, 2018
    Publication date: February 20, 2020
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Dae-Shik KIM, Frank FANG, Atsushi ENDO, Hyeong-wook CHOI, Ming-Hong HAO, Xingfeng BAO, Kuan-Chun HUANG
  • Synthetic route to 2?-deoxy-2?,2?-difluorotetrahydrouridines
    Patent number: 10526362
    Abstract: The present invention relates to methods and intermediates for synthesizing 2?-deoxy-2?,2?-difluorotetrahydrouridine compounds.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: January 7, 2020
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Hyeong-wook Choi, Steven Mathieu, Frank Fang, Bryan Matthew Lewis
  • COMPOUNDS FOR THE TREATMENT OF CANCER
    Publication number: 20190345192
    Abstract: Provided herein are compounds useful for the treatment of cancer.
    Type: Application
    Filed: February 15, 2019
    Publication date: November 14, 2019
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Dae-Shik Kim, Frank Fang, Atsushi Endo, Hyeong-wook Choi, Ming-Hong Hao, Xingfeng Bao, Kuan-Chun Huang
  • EP4 ANTAGONISTS
    Publication number: 20190315754
    Abstract: We provide compounds given by Formula I, which is shown in FIG. 3, or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.
    Type: Application
    Filed: April 23, 2019
    Publication date: October 17, 2019
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Wanjun Zheng, Xiaojie Zhu, Hong Du, Maarten Postema, Yimin Jiang, Jing Li, Robert Yu, Hyeong-wook Choi, Jaemoon Lee, Frank Fang, Daniel Custar
  • Method and Apparatus for Suppression of Spikes Detected by a Proximity Sensor
    Publication number: 20190179281
    Abstract: A method for suppressing a non-periodic random event in a proximity system includes: receiving an output signal generated by a proximity sensor in the proximity system and monitoring at least a magnitude of the output signal; determining whether a spike having a magnitude exceeding a prescribed threshold value has occurred in the output signal; when a spike in the output signal is detected, setting an output of the proximity system to a prescribed level for a prescribed duration of time; when the prescribed duration of time has elapsed, determining whether the output signal meets one or more prescribed criteria indicative of a shutdown condition; when it is determined that the output signal meets the prescribed criteria, setting the output of the proximity system to a level exceeding an alarm threshold; and when it is determined that the output signal fails to meet at least one of the prescribed criteria, releasing suppression of the output of the proximity system.
    Type: Application
    Filed: December 7, 2018
    Publication date: June 13, 2019
    Inventors: Frank Fang, Everett Jesse, Matthew Webster
  • EP4 antagonists
    Patent number: 10316040
    Abstract: We provide compounds given by Formula I, which is shown in FIG. 3, or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: June 11, 2019
    Assignee: Eisai R&D Management Co., LTD.
    Inventors: Wanjun Zheng, Xiaojie Zhu, Hong Du, Maarten Postema, Yimin Jiang, Jing Li, Robert Yu, Hyeong-wook Choi, Jaemoon Lee, Frank Fang, Daniel Custar
  • Compounds for the treatment of cancer
    Patent number: 10246480
    Abstract: Provided herein are compounds useful for the treatment of cancer.
    Type: Grant
    Filed: February 17, 2018
    Date of Patent: April 2, 2019
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Dae-Shik Kim, Frank Fang, Atsushi Endo, Hyeong-Wook Choi, Ming-Hong Hao, Xingfeng Bao, Kuan-Chun Huang
  • EP4 ANTAGONISTS
    Publication number: 20180305362
    Abstract: We provide compounds given by Formula I, which is shown in FIG. 3, or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.
    Type: Application
    Filed: October 14, 2016
    Publication date: October 25, 2018
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Wanjun Zheng, Xiaojie Zhu, Hong Du, Maarten Postema, Yimin Jiang, Jing Li, Robert Yu, Hyeong-wook Choi, Jaemoon Lee, Frank Fang, Daniel Custar
  • Compounds for the Treatment of Cancer
    Publication number: 20180237468
    Abstract: Provided herein are compounds useful for the treatment of cancer.
    Type: Application
    Filed: February 17, 2018
    Publication date: August 23, 2018
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Dae-Shik KIM, Frank FANG, Atsushi ENDO, Hyeong-Wook CHOI, Ming-Hong HAO, Xingfeng BAO, Kuan-Chun HUANG
  • SYNTHETIC ROUTE TO 2'-DEOXY-2',2'-DIFLUOROTETRAHYDROURIDINES
    Publication number: 20180072768
    Abstract: The present invention relates to methods and intermediates for synthesizing 2?-deoxy-2?,2?-difluorotetrahydrouridine compounds.
    Type: Application
    Filed: November 15, 2017
    Publication date: March 15, 2018
    Inventors: Hyeong-wook Choi, Steven Mathieu, Frank Fang, Bryan Matthew Lewis