Abstract: A cooling arrangement for an at least two-stage compressed air generator comprises an intercooler arranged between a first and a second compressor stage, an aftercooler arranged after the second compressor stage, and a subassembly cooler, which absorbs heat from further subassemblies of the compressed air generator. A coolant circuit comprises a main cooler, the cold side supplying a cooled coolant parallel to the respective coolant inlet of the intercooler, of the aftercooler and of the subassembly cooler, and the hot side receiving the heated coolant exiting in parallel at the respective coolant outlet of the intercooler and of the aftercooler. The coolant outlet of the subassembly cooler is connected to a feed inlet of the intercooler and/or of the aftercooler.

Abstract: A cooling arrangement for an at least two-stage compressed air generator comprises an intercooler arranged between a first and a second compressor stage, an aftercooler arranged after the second compressor stage, and a subassembly cooler, which absorbs heat from further subassemblies of the compressed air generator. A coolant circuit comprises a main cooler, the cold side supplying a cooled coolant parallel to the respective coolant inlet of the intercooler, of the aftercooler and of the subassembly cooler, and the hot side receiving the heated coolant exiting in parallel at the respective coolant outlet of the intercooler and of the aftercooler. The coolant outlet of the subassembly cooler is connected to a feed inlet of the intercooler and/or of the aftercooler.

Abstract: A tire includes a pair of sidewalls extending from a respective bead area to a tread. The tread is formed with a plurality of tread elements and a radially outer surface, and a chamber is formed in one of the tread elements. A sensor unit is mounted to the tire and includes a pair of electrical contacts. The polymer plug includes a wire disposed in the chamber. The wire includes proximal ends and a distal end near a radially outer surface of the tread. A liquid polymer is injected into the chamber and cured. An electrical circuit is formed by each proximal end of the wire electrically contacts a respective one of the sensor unit electrical contacts. When the tread element wears down to the distal end of the wire, the wire and the circuit break. A notice is transmitted by the sensor unit when the circuit breaks.

Abstract: A premium vodka having improved mouthfeel and smoothness is provided. In one aspect, the vodka is distilled from curated grains with a select variety of carefully selected olives and Extra Virgin Olive Oil. An objective of using the olives is to enhance the mouthfeel and overall product smoothness. Note the resulting premium vodka is not an olive flavored vodka.

Abstract: A cooling arrangement for an at least two-stage compressed air generator comprises an intercooler arranged between a first and a second compressor stage, an aftercooler arranged after the second compressor stage, and a subassembly cooler, which absorbs heat from further subassemblies of the compressed air generator. A coolant circuit comprises a main cooler, the cold side supplying a cooled coolant parallel to the respective coolant inlet of the intercooler, of the aftercooler and of the subassembly cooler, and the hot side receiving the heated coolant exiting in parallel at the respective coolant outlet of the intercooler and of the aftercooler. The coolant outlet of the subassembly cooler is connected to a feed inlet of the intercooler and/or of the aftercooler.

Abstract: A cooling arrangement for an at least two-stage compressed air generator. The cooling arrangement comprises an intercooler arranged between a first and a second compressor stage, an aftercooler arranged after the second compressor stage, and a subassembly cooler, which absorbs heat from further subassemblies of the compressed air generator. A coolant circuit comprises a main cooler, the cold side supplying a cooled coolant parallel to the respective coolant inlet of the intercooler, of the aftercooler and of the subassembly cooler, and the hot side receiving the heated coolant exiting in parallel at the respective coolant outlet of the intercooler and of the aftercooler. The coolant outlet of the subassembly cooler is connected to a feed inlet of the intercooler and/or of the aftercooler.

Abstract: A tire includes a pair of sidewalls extending from a respective bead area to a tread. The tread is formed with a plurality of tread elements and a radially outer surface. A sensor unit is mounted to the tire and includes a pair of electrical contacts. The tread wear sensor plug includes a cylindrical projection extending through an opening formed in one of the tread elements, a flange, and a wire including proximal ends disposed in the flange and a distal end near a radially outer surface of the projection. An electrical circuit is formed by each proximal end of the wire electrically contacting a respective one of the sensor unit electrical contacts. When the tread element and the cylindrical projection wear down to the distal end of the wire, the wire and the circuit break. A notice is transmitted by the sensor unit when the circuit breaks.

Abstract: A tire includes a pair of sidewalls extending from a respective bead area to a tread. The tread is formed with a plurality of tread elements and a radially outer surface. A sensor unit is mounted to the tire and includes a pair of electrical contacts. The tread wear sensor plug includes a cylindrical projection extending through an opening formed in one of the tread elements, a flange, and a wire including proximal ends disposed in the flange and a distal end near a radially outer surface of the projection. An electrical circuit is formed by each proximal end of the wire electrically contacting a respective one of the sensor unit electrical contacts. When the tread element and the cylindrical projection wear down to the distal end of the wire, the wire and the circuit break. A notice is transmitted by the sensor unit when the circuit breaks.

Abstract: A tire includes a pair of sidewalls extending from a respective bead area to a tread. The tread is formed with a plurality of tread elements and a radially outer surface, and a chamber is formed in one of the tread elements. A sensor unit is mounted to the tire and includes a pair of electrical contacts. The polymer plug includes a wire disposed in the chamber. The wire includes proximal ends and a distal end near a radially outer surface of the tread. A liquid polymer is injected into the chamber and cured. An electrical circuit is formed by each proximal end of the wire electrically contacts a respective one of the sensor unit electrical contacts. When the tread element wears down to the distal end of the wire, the wire and the circuit break. A notice is transmitted by the sensor unit when the circuit breaks.

Abstract: The invention relates to a cooling arrangement for an at least two-stage compressed air generator (01). The cooling arrangement comprises an intercooler (04), which is arranged between a first and a second compressor stage (02, 03), an aftercooler (05), which is arranged after the second compressor stage (03), and a subassembly cooler (08), which absorbs heat from further subassemblies of the compressed air generator (01). A coolant circuit comprises a main cooler (07), the cold side of which supplies a cooled coolant having a low temperature parallel to the respective coolant inlet of the intercooler (04), of the aftercooler (05) and of the subassembly cooler (08), and the hot side of which receives the heated coolant having a high temperature exiting in parallel at the respective coolant outlet of the intercooler (04) and of the aftercooler (05). The coolant outlet of the subassembly cooler (08) is connected to a feed inlet (12) of the intercooler (04) and/or of the aftercooler (05).

Abstract: The present invention provides 5-[5]-[2-cycloalkyl]-6-pyridazin-3-yl]-1H-pyrimidine-2,4-dione compounds, or pharmaceutically acceptable salts thereof, that inhibit the activity of CD73 and are useful in treating cancer.

Abstract: The present invention provides 5-[5]-[2-cycloalkyl]-6-pyridazin-3-yl]-1H-pyrimidine-2,4-dione compounds, or pharmaceutically acceptable salts thereof, that inhibit the activity of CD73 and are useful in treating cancer.

Abstract: The invention relates to a compressor system for generating compressed air. It comprises a drive, a driven compressor, a lubricant cooler, a compressed air cooler and a blower unit. The blower unit has at least two blowers that can be controlled independent of one another, which convey cooling air to first and second cooling chambers that are separated from one another, wherein the first cooling chamber conveys the cooling air to the lubricant cooler, and the second cooling chamber conveys the cooling air to the compressed air cooler. The lubricant cooler and the compressed air cooler have an arrangement that is offset to one another in such a way that the axes of their inflow and outflow flanges, arranged on their lateral walls, are located in different planes. The invention also relates to a method for operating a compressor system that generates compressed air, wherein at least two control signals that are independent of one another are provided for two blowers.

Abstract: An off-road vehicle includes a body having at least one fender positioned over at least one wheel or track of the off-road vehicle. The at least one wheel or track is configured to engage a ground surface. The off-road vehicle also includes at least one spatial locating antenna positioned beneath the at least one fender. A top side of the at least one fender is positioned above the at least one spatial locating antenna relative to the ground surface, and the top side extends beyond a lateral extent and a longitudinal extent of the at least one spatial locating antenna.

Abstract: The present invention relates primarily to a method for controlling the rotational rate of a compressor, which controls, in particular, the rotational rate of a rotating compression element of the compressor. The invention furthermore relates to a compressor, e.g. a compressor for generating pressurized air. The compressor is to be operated at a rotational rate, when in operation, with a mean value that is at least as high as a minimum mean value, in order to ensure the functionality of the compressor. According to the method, a temporally variable target rotational rate of the compressor that is necessary for obtaining a temporally variable output performance from a compressor is determined. In accordance with the invention, a lower rotational rate limit is raised if the temporal mean of the variable target rotational rate is lower than the minimal mean value for the rotational rate of the compressor.

Abstract: A compressor system (01) with a system housing (02), in which are arranged heat generating system components (06) comprising at least one compressor stage (201) for compressing a gaseous medium, an air water cooler (12), a blower (15) which generates a cooling air flow (16), and air conducting elements. A cooling air channel (07) is configured which has an inlet opening (08) in the upper section of the system housing (02) and an outlet opening (09) in the lower section of the system housing (02), wherein upper air conducting elements (13) are positioned in order to conduct the cooling air flow (16) after flowing through the air water cooler (12) to the inlet opening (08), and lower air conducting elements (17) are positioned in order to conduct the cooling air flow (16) from the outlet opening (09) to the system components (06).

Abstract: A mixing valve arrangement for a hydraulic system is provided with a medium cavity, in which a mixing cylinder, a first and a second inlet chamber as well as an outlet are provided. A mixing piston is axially mounted and movable in the mixing cylinder, provided with a flow path with an inlet opening, a variable cross-section of said inlet opening culminating into the first and/or the second inlet chamber, according to the axial position of the mixing piston, and with an outlet opening culminating in the outlet of the mixing cylinder. A thrust rod is axially mounted and movable and connected to the mixing piston, to change the axial position thereof. A drive is connected as an actuator to the thrust rod, for the axial movement of the same. The drive is an electrical motor, which is completely arranged inside the medium cavity.

Abstract: The present application relates generally to a method for vision correction using corneal collagen crosslinking (“CCXL”), in which the physician is able to precisely control the pattern of ultraviolet (“UV”) energy delivered to the cornea, by means of a programmable masking array placed between the UV source and the cornea. A CCXL LCD masked is used to create various patterns of “on” and “off” pixels. The physician is able to control the degree of polarization of the LCD pixels, thereby allowing the physician to create various patterns of UV irradiation and thus, varying levels of CCXL.

Abstract: A fundus camera for photographing a fundus of an eye that includes a plurality of light sources with differing frequencies for illuminating the fundus, a plurality of fixation lights configured to orient the fundus in varying positions, and an imaging sensor. The fundus camera further includes at least one processor configured to cause the illumination of the plurality of light sources and the plurality of fixation lights in a predetermined pattern to obtain a plurality of narrow bandwidth images of the fundus and to manipulate and stitch the resulting narrow bandwidth images into a composite color image.

Abstract: A device and method for applying light to the cornea of the eye as, for example, to promote crosslinking of collagen in the cornea for vision correction. The device may include a structure having form and size similar to a conventional contact lens. The structure may include an optically dispersive element such as a mass of an optically dispersive material that may be contained in a cavity of a reflective element. Light applied to the dispersive mass as, for example, by an optical fiber connected to the structure is dispersed in the structure and passes into the cornea. The patient may blink or close the eye during the procedure, which increases patient comfort and aids in maintaining hydration of the cornea.